Topical Anti-TNFα Agent Licaminlimab (OCS-02) Relieves Persistent Ocular Discomfort in Severe Dry Eye Disease: A Randomized Phase II Study

Purpose: To assess the efficacy, safety, and pharmacokinetics of new topical ocular anti-TNFα antibody fragment licaminlimab in the relief of persistent ocular discomfort in severe dry eye disease (DED). Patients and Methods: Patients with ≥ 6-month history of DED, regular use of artificial tears, a...

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Bibliographic Details

Published in:	Clinical ophthalmology (Auckland, N.Z.) Vol. 16; pp. 2167 - 2177
Main Authors:	Shettle, Lee, McLaurin, Eugene, Martel, Joseph, Seaman, John W, Weissgerber, Georges
Format:	Journal Article
Language:	English
Published:	Auckland Taylor & Francis Ltd 01.01.2022 Dove Dove Medical Press
Subjects:	anti-tumor necrosis factor α Clinical Trial Report Cornea Cytokines Diabetic retinopathy dry eye disease Eye diseases Inflammation Patients Questionnaires single chain antibody fragment Surgery topical treatment Canada United States > US
ISSN:	1177-5483, 1177-5467, 1177-5483
Online Access:	Get full text
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