Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer

Early metastasis to lymph nodes is a frequent complication in human breast cancer. However, the extent to which this depends on lymphangiogenesis or on invasion of existing lymph vessels remains controversial. Although proliferating intratumoural lymphatics that promote nodal metastasis have been de...

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Bibliographic Details
Published in:	The Journal of pathology Vol. 200; no. 2; pp. 195 - 206
Main Authors:	Williams, Cory SM, Leek, Russell D, Robson, Alistair M, Banerji, Suneale, Prevo, Remko, Harris, Adrian L, Jackson, David G
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01.06.2003 Wiley
Subjects:	Adult Aged Aged, 80 and over Biological and medical sciences breast cancer Breast Neoplasms - blood supply Breast Neoplasms - metabolism Breast Neoplasms - pathology Female Glycoproteins - metabolism Gynecology. Andrology. Obstetrics Humans Immunoenzyme Techniques lymphangiogenesis Lymphatic Metastasis Lymphatic System - pathology LYVE-1 Macrophages - pathology Mammary gland diseases Medical sciences metastasis Middle Aged Neoplasm Invasiveness Neoplasm Proteins - metabolism Neovascularization, Pathologic - pathology Statistics as Topic Tumors VEGF-C Vesicular Transport Proteins Human Immunohistochemistry Carcinoma Lymph node Cytokine Malignant lymphadenopathy Lymphatic breast cancer VEGF-C Malignant tumor Pathology Mammary gland diseases Angiogenesis Vascular endothelium growth factor metastasis Tumor progression lymphangiogenesis Metastatic Mammary gland Molecular biology Immunofluorescence LYVE-1 Growth factor
ISSN:	0022-3417, 1096-9896
Online Access:	Get full text
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