Normal‐weight obesity and cardiometabolic risk: A 7‐year longitudinal study in girls from prepuberty to early adulthood
Objective To study whether normal‐weight obesity in childhood is associated with increased cardiometabolic risk in early adulthood. Methods This study assessed data for 236 girls followed from prepuberty to early adulthood. Growth chart data were obtained from birth to 18 years. Body composition was...
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| Published in: | Obesity (Silver Spring, Md.) Vol. 25; no. 6; pp. 1077 - 1082 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Blackwell Publishing Ltd
01.06.2017
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| Subjects: | |
| ISSN: | 1930-7381, 1930-739X, 1930-739X |
| Online Access: | Get full text |
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| Summary: | Objective
To study whether normal‐weight obesity in childhood is associated with increased cardiometabolic risk in early adulthood.
Methods
This study assessed data for 236 girls followed from prepuberty to early adulthood. Growth chart data were obtained from birth to 18 years. Body composition was assessed by dual‐energy x‐ray absorptiometry and cardiometabolic risk by calculating continuous clustered risk score (at ages 11, 14, and 18). The association of body weight status with cardiometabolic risk from childhood to early adulthood was examined.
Results
Subjects with normal‐weight obesity were virtually indistinguishable from their normal‐weight lean peers in terms of relative body weight and BMI but had significantly higher fat mass (7.1‐7.3 kg) and cardiometabolic risk already in childhood, and this difference persisted into early adulthood (P < 0.001 for all).
Conclusions
Children and adolescents with normal body weight and high body fat percentage may be at increased risk for cardiometabolic morbidity in adulthood. Body fatness may be of utility in clinical practice to effectively identify children and adolescents at risk and to permit recommendation of lifestyle changes that could translate to lower risks of cardiovascular diseases in the future. |
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| Bibliography: | The authors declared no conflict of interest. This work was supported financially by the Academy of Finland, the Ministry of Education of Finland, the University of Jyväskylä, the China State Sport General Administration (Grant 2013B040), the National Nature Science Foundation of China (Grant 31571219), the Shanghai Jiao Tong University Zhiyuan Foundation (Grant CP2014013), and EVO research grants (years 2012/2013) from Oulu University Hospital. The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Disclosure Funding agencies PW participated in data collection, analyzed data, and wrote the manuscript. TT, YS, and NW participated in analyzing, writing, and editing the manuscript. AV participated in writing and editing the manuscript. MA participated in study design, data collection, and writing and editing the manuscript. SC designed the study and participated in data collection and analysis and the writing and editing of the manuscript. All authors had final approval of the submitted version. PW and SC had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Author contributions ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ISSN: | 1930-7381 1930-739X 1930-739X |
| DOI: | 10.1002/oby.21838 |