The relationship between skin function, barrier properties, and body‐dependent factors

Background Skin is a multilayer interface between the body and the environment, responsible for many important functions, such as temperature regulation, water transport, sensation, and protection from external triggers. Objectives This paper provides an overview of principal factors that influence...

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Published in:Skin research and technology Vol. 24; no. 2; pp. 165 - 174
Main Authors: Dąbrowska, A.K., Spano, F., Derler, S., Adlhart, C., Spencer, N.D., Rossi, R.M.
Format: Journal Article
Language:English
Published: England John Wiley & Sons, Inc 01.05.2018
Subjects:
Absorption
age
Body temperature
diversity
Environmental regulations
ethnicity
gender
human skin
In vivo methods and tests
Minority & ethnic groups
Properties (attributes)
Skin
skin barrier
skin function
skin permeability
skin properties
Water transport
skin barrier
diversity
ethnicity
gender
human skin
skin properties
skin permeability
age
skin function
ISSN:0909-752X, 1600-0846, 1600-0846
Online Access:Get full text
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Summary:Background Skin is a multilayer interface between the body and the environment, responsible for many important functions, such as temperature regulation, water transport, sensation, and protection from external triggers. Objectives This paper provides an overview of principal factors that influence human skin and describes the diversity of skin characteristics, its causes and possible consequences. It also discusses limitations in the barrier function of the skin, describing mechanisms of absorption. Methods There are a number of in vivo investigations focusing on the diversity of human skin characteristics with reference to barrier properties and body‐dependent factors. Results Skin properties vary among individuals of different age, gender, ethnicity, and skin types. In addition, skin characteristics differ depending on the body site and can be influenced by the body‐mass index and lifestyle. Although one of the main functions of the skin is to act as a barrier, absorption of some substances remains possible. Conclusions Various factors can alter human skin properties, which can be reflected in skin function and the quality of everyday life. Skin properties and function are strongly interlinked.
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ISSN:0909-752X
1600-0846
1600-0846
DOI:10.1111/srt.12424