AMPK/mTOR pathway significance in healthy liver and non‐alcoholic fatty liver disease and its progression

Obesity is related to several organs, but the liver is particularly affected. Adenosine monophosphate‐activated protein kinase (AMPK) is a cellular energy sensor and regulator of liver lipid dysfunction and glucose metabolism. The mechanistic target of rapamycin (mTOR) is a protein kinase regulating...

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Bibliographic Details
Published in:	Journal of gastroenterology and hepatology Vol. 38; no. 11; pp. 1868 - 1876
Main Authors:	Marcondes‐de‐Castro, Ilitch Aquino, Reis‐Barbosa, Pedro Henrique, Marinho, Thatiany Souza, Aguila, Marcia Barbosa, Mandarim‐de‐Lacerda, Carlos Alberto
Format:	Journal Article
Language:	English
Published:	Australia Wiley Subscription Services, Inc 01.11.2023
Subjects:	Adenosine kinase Adipogenesis AMP AMPK/mTOR pathway Autophagy Cell survival Cirrhosis Fatty acids Fatty liver Forkhead protein Glucose metabolism Hepatocellular carcinoma Insulin resistance Kinases Lipid metabolism Lipogenesis Liver diseases Metabolism non‐alcoholic fatty liver disease Obesity Phagosomes Phosphorylation Protein kinase Protein turnover Proteins Rapamycin TOR protein autophagy non-alcoholic fatty liver disease AMPK/mTOR pathway obesity lipid metabolism
ISSN:	0815-9319, 1440-1746, 1440-1746
Online Access:	Get full text
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