Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis sensu stricto , as well as two lineages (L5 and L6) traditionally referred to as Mycobacterium africanum . Strains of L5 and L6 ar...

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Bibliographic Details
Published in:	Microbial genomics Vol. 7; no. 2
Main Authors:	Coscolla, Mireia, Gagneux, Sebastien, Menardo, Fabrizio, Loiseau, Chloé, Ruiz-Rodriguez, Paula, Borrell, Sonia, Otchere, Isaac Darko, Asante-Poku, Adwoa, Asare, Prince, Sánchez-Busó, Leonor, Gehre, Florian, Sanoussi, C. N’Dira, Antonio, Martin, Affolabi, Dissou, Fyfe, Janet, Beckert, Patrick, Niemann, Stefan, Alabi, Abraham S., Grobusch, Martin P., Kobbe, Robin, Parkhill, Julian, Beisel, Christian, Fenner, Lukas, Böttger, Erik C., Meehan, Conor J., Harris, Simon R., de Jong, Bouke C., Yeboah-Manu, Dorothy, Brites, Daniela
Format:	Journal Article
Language:	English
Published:	England Microbiology Society 01.02.2021
Subjects:	Africa, Eastern Africa, Western Drug Resistance, Bacterial Evolution, Molecular Genome, Bacterial High-Throughput Nucleotide Sequencing Humans Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Phylogeny Phylogeography Tuberculosis - microbiology Whole Genome Sequencing - methods Africa, Eastern Africa, Western genome diversity evolution Mycobacterium tuberculosis mycobacteria Mycobacterium africanum
ISSN:	2057-5858, 2057-5858
Online Access:	Get full text
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