Acute Invasive Rhino-Orbital Mucormycosis in a Patient With COVID-19-Associated Acute Respiratory Distress Syndrome

Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at particularly high risk of complications and mortality in the setting of SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19)-related a...

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Veröffentlicht in:Ophthalmic plastic and reconstructive surgery Jg. 37; H. 2; S. e40
Hauptverfasser: Mekonnen, Zesemayat K, Ashraf, Davin C, Jankowski, Tyler, Grob, Seanna R, Vagefi, M Reza, Kersten, Robert C, Simko, Jeffry P, Winn, Bryan J
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 01.03.2021
Schlagworte:
COVID-19 - complications
Humans
Mucormycosis - complications
Mucormycosis - diagnosis
Mycoses - diagnosis
Nose Diseases - microbiology
Orbital Diseases - microbiology
Respiratory Distress Syndrome - diagnosis
Respiratory Distress Syndrome - etiology
SARS-CoV-2 - isolation & purification
Sinusitis
ISSN:1537-2677, 1537-2677
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Abstract Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at particularly high risk of complications and mortality in the setting of SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome. The authors present a case of acute invasive fungal rhino-orbital mucormycosis in a patient with COVID-19 and discuss the prevalence, diagnosis, and treatment of fungal coinfections in COVID-19. Prompt recognition, initiation of therapy, and consideration of the challenges of rapidly evolving COVID-19 therapy guidelines are important for improving patient survival.
AbstractList Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at particularly high risk of complications and mortality in the setting of SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome. The authors present a case of acute invasive fungal rhino-orbital mucormycosis in a patient with COVID-19 and discuss the prevalence, diagnosis, and treatment of fungal coinfections in COVID-19. Prompt recognition, initiation of therapy, and consideration of the challenges of rapidly evolving COVID-19 therapy guidelines are important for improving patient survival.
Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at particularly high risk of complications and mortality in the setting of SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome. The authors present a case of acute invasive fungal rhino-orbital mucormycosis in a patient with COVID-19 and discuss the prevalence, diagnosis, and treatment of fungal coinfections in COVID-19. Prompt recognition, initiation of therapy, and consideration of the challenges of rapidly evolving COVID-19 therapy guidelines are important for improving patient survival.Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at particularly high risk of complications and mortality in the setting of SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome. The authors present a case of acute invasive fungal rhino-orbital mucormycosis in a patient with COVID-19 and discuss the prevalence, diagnosis, and treatment of fungal coinfections in COVID-19. Prompt recognition, initiation of therapy, and consideration of the challenges of rapidly evolving COVID-19 therapy guidelines are important for improving patient survival.
Author Winn, Bryan J
Mekonnen, Zesemayat K
Ashraf, Davin C
Vagefi, M Reza
Jankowski, Tyler
Simko, Jeffry P
Kersten, Robert C
Grob, Seanna R
Author_xml – sequence: 1
  givenname: Zesemayat K
  surname: Mekonnen
  fullname: Mekonnen, Zesemayat K
  organization: School of Medicine
– sequence: 2
  givenname: Davin C
  surname: Ashraf
  fullname: Ashraf, Davin C
  organization: Department of Ophthalmology
– sequence: 3
  givenname: Tyler
  surname: Jankowski
  fullname: Jankowski, Tyler
  organization: Department of Pathology, University of California, San Francisco
– sequence: 4
  givenname: Seanna R
  surname: Grob
  fullname: Grob, Seanna R
  organization: Department of Ophthalmology
– sequence: 5
  givenname: M Reza
  surname: Vagefi
  fullname: Vagefi, M Reza
  organization: Department of Ophthalmology
– sequence: 6
  givenname: Robert C
  surname: Kersten
  fullname: Kersten, Robert C
  organization: Department of Ophthalmology
– sequence: 7
  givenname: Jeffry P
  surname: Simko
  fullname: Simko, Jeffry P
  organization: Department of Pathology, University of California, San Francisco
– sequence: 8
  givenname: Bryan J
  surname: Winn
  fullname: Winn, Bryan J
  organization: Ophthalmology Section, Surgical Service, San Francisco Veterans Affairs Medical Center, San Francisco, California, U.S.A
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Snippet Acute invasive fungal rhinosinusitis is a rare, although highly morbid, infection primarily affecting immunosuppressed individuals. The same population is at...
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SubjectTerms COVID-19 - complications
Humans
Mucormycosis - complications
Mucormycosis - diagnosis
Mycoses - diagnosis
Nose Diseases - microbiology
Orbital Diseases - microbiology
Respiratory Distress Syndrome - diagnosis
Respiratory Distress Syndrome - etiology
SARS-CoV-2 - isolation & purification
Sinusitis
Title Acute Invasive Rhino-Orbital Mucormycosis in a Patient With COVID-19-Associated Acute Respiratory Distress Syndrome
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