American College of Gastroenterology Guidelines: Management of Acute Pancreatitis

Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients an...

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Published in:The American journal of gastroenterology Vol. 119; no. 3; pp. 419 - 437
Main Authors: Tenner, Scott, Vege, Santhi Swaroop, Sheth, Sunil G., Sauer, Bryan, Yang, Allison, Conwell, Darwin L., Yadlapati, Rena H., Gardner, Timothy B.
Format: Journal Article
Language:English
Published: Philadelphia, PA Wolters Kluwer 01.03.2024
Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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ISSN:0002-9270, 1572-0241, 1572-0241
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Abstract Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.
AbstractList Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.
Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.
Author Conwell, Darwin L.
Sauer, Bryan
Tenner, Scott
Gardner, Timothy B.
Sheth, Sunil G.
Yadlapati, Rena H.
Vege, Santhi Swaroop
Yang, Allison
Author_xml – sequence: 1
  givenname: Scott
  surname: Tenner
  fullname: Tenner, Scott
  organization: State University of New York, Health Sciences Center, Brooklyn, New York, USA
– sequence: 2
  givenname: Santhi Swaroop
  surname: Vege
  fullname: Vege, Santhi Swaroop
  email: vege.santhi@mayo.edu
  organization: Mayo Clinic, Rochester, Minnesota, USA
– sequence: 3
  givenname: Sunil G.
  surname: Sheth
  fullname: Sheth, Sunil G.
  email: ssheth@bidmc.harvard.edu
  organization: Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
– sequence: 4
  givenname: Bryan
  surname: Sauer
  fullname: Sauer, Bryan
  email: bs2dd@uvahealth.org
  organization: University of Virginia, Charlottesville, Virginia, USA
– sequence: 5
  givenname: Allison
  surname: Yang
  fullname: Yang, Allison
  email: alli.yang@gmail.com
  organization: Weill Cornell Medicine, New York, New York, USA
– sequence: 6
  givenname: Darwin L.
  surname: Conwell
  fullname: Conwell, Darwin L.
  email: darwin.conwell@uky.edu
  organization: University of Kentucky, Lexington, Kentucky, USA
– sequence: 7
  givenname: Rena H.
  surname: Yadlapati
  fullname: Yadlapati, Rena H.
  email: renahyadlapati@gmail.com
  organization: University of California, San Diego, San Diego, California, USA
– sequence: 8
  givenname: Timothy B.
  surname: Gardner
  fullname: Gardner, Timothy B.
  email: Timothy.B.Gardner@hitchcock.org
  organization: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38857482$$D View this record in MEDLINE/PubMed
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Snippet Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital...
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SubjectTerms Abdomen
Acute Disease
Cholangiopancreatography, Endoscopic Retrograde
Clinical trials
Disease
Etiology
Gastroenterology
Humans
Magnetic resonance imaging
Mortality
Necrosis
Pain
Pancreatitis
Pancreatitis - diagnosis
Pancreatitis - etiology
Pancreatitis - therapy
Patients
United States
Title American College of Gastroenterology Guidelines: Management of Acute Pancreatitis
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https://www.ncbi.nlm.nih.gov/pubmed/38857482
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Volume 119
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