American College of Gastroenterology Guidelines: Management of Acute Pancreatitis
Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients an...
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| Published in: | The American journal of gastroenterology Vol. 119; no. 3; pp. 419 - 437 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Philadelphia, PA
Wolters Kluwer
01.03.2024
Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins |
| Subjects: | |
| ISSN: | 0002-9270, 1572-0241, 1572-0241 |
| Online Access: | Get full text |
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| Abstract | Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP. |
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| AbstractList | Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP. Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP. |
| Author | Conwell, Darwin L. Sauer, Bryan Tenner, Scott Gardner, Timothy B. Sheth, Sunil G. Yadlapati, Rena H. Vege, Santhi Swaroop Yang, Allison |
| Author_xml | – sequence: 1 givenname: Scott surname: Tenner fullname: Tenner, Scott organization: State University of New York, Health Sciences Center, Brooklyn, New York, USA – sequence: 2 givenname: Santhi Swaroop surname: Vege fullname: Vege, Santhi Swaroop email: vege.santhi@mayo.edu organization: Mayo Clinic, Rochester, Minnesota, USA – sequence: 3 givenname: Sunil G. surname: Sheth fullname: Sheth, Sunil G. email: ssheth@bidmc.harvard.edu organization: Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA – sequence: 4 givenname: Bryan surname: Sauer fullname: Sauer, Bryan email: bs2dd@uvahealth.org organization: University of Virginia, Charlottesville, Virginia, USA – sequence: 5 givenname: Allison surname: Yang fullname: Yang, Allison email: alli.yang@gmail.com organization: Weill Cornell Medicine, New York, New York, USA – sequence: 6 givenname: Darwin L. surname: Conwell fullname: Conwell, Darwin L. email: darwin.conwell@uky.edu organization: University of Kentucky, Lexington, Kentucky, USA – sequence: 7 givenname: Rena H. surname: Yadlapati fullname: Yadlapati, Rena H. email: renahyadlapati@gmail.com organization: University of California, San Diego, San Diego, California, USA – sequence: 8 givenname: Timothy B. surname: Gardner fullname: Gardner, Timothy B. email: Timothy.B.Gardner@hitchcock.org organization: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38857482$$D View this record in MEDLINE/PubMed |
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| ID | FETCH-LOGICAL-c4535-9994669c0bcd3c53a7110c837f0688f0911d7433f640f9ff72d98e35100a8de03 |
| IEDL.DBID | 7X7 |
| ISICitedReferencesCount | 141 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001236991100005&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0002-9270 1572-0241 |
| IngestDate | Sun Sep 28 00:55:03 EDT 2025 Tue Oct 07 07:35:38 EDT 2025 Wed Aug 06 16:36:16 EDT 2025 Tue Nov 18 19:54:17 EST 2025 Sat Nov 29 07:40:46 EST 2025 Mon Aug 04 20:40:26 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | English |
| License | Copyright © 2024 by The American College of Gastroenterology. |
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| Notes | Correspondence: Santhi Swaroop Vege, MD, MACG. E-mail: vege.santhi@mayo.edu. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Instructional Material/Guideline-3 content type line 23 |
| PMID | 38857482 |
| PQID | 2937310721 |
| PQPubID | 2041977 |
| PageCount | 19 |
| ParticipantIDs | proquest_miscellaneous_3066792111 proquest_journals_2937310721 pubmed_primary_38857482 crossref_citationtrail_10_14309_ajg_0000000000002645 crossref_primary_10_14309_ajg_0000000000002645 wolterskluwer_health_10_14309_ajg_0000000000002645 |
| PublicationCentury | 2000 |
| PublicationDate | 2024-March |
| PublicationDateYYYYMMDD | 2024-03-01 |
| PublicationDate_xml | – month: 03 year: 2024 text: 2024-March |
| PublicationDecade | 2020 |
| PublicationPlace | Philadelphia, PA |
| PublicationPlace_xml | – name: Philadelphia, PA – name: United States – name: New York |
| PublicationTitle | The American journal of gastroenterology |
| PublicationTitleAbbrev | Am J Gastroenterol |
| PublicationTitleAlternate | Am J Gastroenterol |
| PublicationYear | 2024 |
| Publisher | Wolters Kluwer Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins |
| Publisher_xml | – name: Wolters Kluwer – name: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins |
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| SubjectTerms | Abdomen Acute Disease Cholangiopancreatography, Endoscopic Retrograde Clinical trials Disease Etiology Gastroenterology Humans Magnetic resonance imaging Mortality Necrosis Pain Pancreatitis Pancreatitis - diagnosis Pancreatitis - etiology Pancreatitis - therapy Patients United States |
| Title | American College of Gastroenterology Guidelines: Management of Acute Pancreatitis |
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