Human Antibody Responses Following Vaccinia Immunization Using Protein Microarrays and Correlation With Cell-Mediated Immunity and Antibody-Dependent Cellular Cytotoxicity Responses

There are limited data regarding immunological correlates of protection for the modified vaccinia Ankara (MVA) smallpox vaccine. A total of 523 vaccinia-naive subjects were randomized to receive 2 vaccine doses, as lyophilized MVA given subcutaneously, liquid MVA given subcutaneously (liquid-SC grou...

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Veröffentlicht in:	The Journal of infectious diseases Jg. 224; H. 8; S. 1372
Hauptverfasser:	Frey, Sharon E, Stapleton, Jack T, Ballas, Zuhair K, Rasmussen, Wendy L, Kaufman, Thomas M, Blevins, Tammy P, Jensen, Travis L, Davies, D Huw, Tary-Lehmann, Magdalena, Chaplin, Paul, Hill, Heather, Goll, Johannes B
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 28.10.2021
Schlagworte:	Antibody Formation Antibody-Dependent Cell Cytotoxicity Antigens, Viral Humans Immunity, Cellular Immunization Protein Array Analysis Smallpox Vaccine - administration & dosage Vaccines, Attenuated Vaccines, DNA - administration & dosage Vaccinia Vaccinia virus - immunology Viral Vaccines - administration & dosage correlation of protection modified vaccinia Ankara membrane proteins protein microarray vaccinia western reserve smallpox ADCC ELISPOT antibody responses MVA vaccine
ISSN:	1537-6613, 1537-6613
Online-Zugang:	Weitere Angaben
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