Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

Basal breast cancer cells feature high expression of the Src family kinase Lyn that has been implicated in the pathogenicity of this disease. In this study, we identified novel Lyn kinase substrates, the most prominent of which was the atypical kinase SgK269 (PEAK1). In breast cancer cells, SgK269 e...

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Vydáno v:	Cancer research (Chicago, Ill.) Ročník 73; číslo 6; s. 1969
Hlavní autoři:	Croucher, David R, Hochgräfe, Falko, Zhang, Luxi, Liu, Ling, Lyons, Ruth J, Rickwood, Danny, Tactacan, Carole M, Browne, Brigid C, Ali, Naveid, Chan, Howard, Shearer, Robert, Gallego-Ortega, David, Saunders, Darren N, Swarbrick, Alexander, Daly, Roger J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 15.03.2013
Témata:	Breast Neoplasms - enzymology Breast Neoplasms - pathology Cell Division Cell Line, Tumor Female Humans Microscopy, Fluorescence Neoplasm Invasiveness Phosphorylation Polymerase Chain Reaction Protein-Tyrosine Kinases - metabolism Signal Transduction src-Family Kinases - metabolism
ISSN:	1538-7445, 1538-7445
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