Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity

We explored the role of transmembrane 6 superfamily member 2 (TM6SF2) rs58542926 C/T nonsynonymous (p.Glu167Lys) variant in genetic susceptibility to nonalcoholic fatty liver disease (NAFLD) and disease severity. A total of 361 individuals (135 control subjects and 226 patients with histologically p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hepatology (Baltimore, Md.) Jg. 61; H. 2; S. 515 - 525
Hauptverfasser:	Sookoian, Silvia, Castaño, Gustavo O., Scian, Romina, Mallardi, Pablo, Fernández Gianotti, Tomas, Burgueño, Adriana L., San Martino, Julio, Pirola, Carlos J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wolters Kluwer Health, Inc 01.02.2015
Schlagworte:	Adult Aged Alleles Cardiovascular Diseases - genetics Case-Control Studies Confidence intervals Disease Progression Female Fibrosis Genetic Predisposition to Disease Genetic Variation Hepatology Humans Liver Liver - metabolism Liver - pathology Liver diseases Male Medical research Membrane Proteins - genetics Middle Aged Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - pathology Polymorphism, Single Nucleotide
ISSN:	0270-9139, 1527-3350, 1527-3350
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!