Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity

We explored the role of transmembrane 6 superfamily member 2 (TM6SF2) rs58542926 C/T nonsynonymous (p.Glu167Lys) variant in genetic susceptibility to nonalcoholic fatty liver disease (NAFLD) and disease severity. A total of 361 individuals (135 control subjects and 226 patients with histologically p...

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Vydáno v:	Hepatology (Baltimore, Md.) Ročník 61; číslo 2; s. 515 - 525
Hlavní autoři:	Sookoian, Silvia, Castaño, Gustavo O., Scian, Romina, Mallardi, Pablo, Fernández Gianotti, Tomas, Burgueño, Adriana L., San Martino, Julio, Pirola, Carlos J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Wolters Kluwer Health, Inc 01.02.2015
Témata:	Adult Aged Alleles Cardiovascular Diseases - genetics Case-Control Studies Confidence intervals Disease Progression Female Fibrosis Genetic Predisposition to Disease Genetic Variation Hepatology Humans Liver Liver - metabolism Liver - pathology Liver diseases Male Medical research Membrane Proteins - genetics Middle Aged Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - pathology Polymorphism, Single Nucleotide
ISSN:	0270-9139, 1527-3350, 1527-3350
On-line přístup:	Získat plný text
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