Roles of irregularity of pore morphology in osteogenesis of Voronoi scaffolds: From the perspectives of MSC adhesion and mechano-regulated osteoblast differentiation

Bone scaffolds designed based on the Voronoi-tessellation algorithm have been increasingly studied owing to their structural similarity with natural cancellous bone. The irregularity of pore morphology (IPM) influences the osteogenesis efficiency of Voronoi scaffolds since it may alter the static an...

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Bibliographic Details
Published in:	Journal of biomechanics Vol. 151; p. 111542
Main Authors:	Lu, Teng, Sun, Zhongwei, Jia, Cunwei, Ren, Jiakun, Li, Jie, Ma, Zhiyuan, Zhang, Jing, Li, Jialiang, Zhang, Ting, Zang, Quanjin, Yang, Baohui, Yang, Pinglin, Wang, Dong, Li, Haopeng, Qin, Jie, He, Xijing
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01.04.2023 Elsevier Limited
Subjects:	Adhesion Algorithms Animal research Animals Biomechanics Bone and Bones Cancellous bone Cell adhesion Cell Differentiation Computational fluid dynamics Computer applications Design defects Efficiency Finite element method Hematoma Irregularities Irregularity of pore morphology Mathematical models Mechano-regulated differentiation Mesenchymal stem cells Microenvironments Morphology Osteoblastogenesis Osteoblasts Osteogenesis Osteogenesis efficiency Performance prediction Reynolds number Scaffolds Shear strain Stem cells Tensors Tessellation Tissue Scaffolds - chemistry Titanium alloys Tortuosity Viscosity Voronoi scaffold United States > US CFD DPM Voronoi scaffold FSS IPM Mechano-regulated differentiation OSS Irregularity of pore morphology BV/TV Osteogenesis efficiency Cell adhesion MSC MrOD Mesenchymal stem cells FE
ISSN:	0021-9290, 1873-2380, 1873-2380
Online Access:	Get full text
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