Diagnostic performances and thresholds: The key to harmonization in serological SARS-CoV-2 assays?

•Serological assays for SARS-CoV-2 are widely available.•Data on diagnostic sensitivity, specificity and likelihood ratio are needed.•The identification of reliable thresholds improves diagnostic accuracy.•The negative predictive value is a valuable clinical information. The evaluation of severe acu...

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Bibliographic Details
Published in:	Clinica chimica acta Vol. 509; pp. 1 - 7
Main Authors:	Plebani, Mario, Padoan, Andrea, Negrini, Davide, Carpinteri, Benedetta, Sciacovelli, Laura
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.10.2020
Subjects:	Adolescent Adult Aged Aged, 80 and over Antibodies Betacoronavirus - isolation & purification Child Clinical performances Coronavirus Infections - blood Coronavirus Infections - diagnosis COVID-19 Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - standards Female Humans Male Middle Aged Pandemics Pneumonia, Viral - blood Pneumonia, Viral - diagnosis Reproducibility of Results Reverse Transcriptase Polymerase Chain Reaction - methods Reverse Transcriptase Polymerase Chain Reaction - standards SARS-CoV-2 Serologic Tests - methods Serologic Tests - standards Young Adult COVID-19 Antibodies Clinical performances SARS-CoV-2
ISSN:	0009-8981, 1873-3492, 1873-3492
Online Access:	Get full text
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