Sweetened kallikrein-related peptidases (KLKs): glycan trees as potential regulators of activation and activity

Most kallikrein-related peptidases (KLKs) are N-glycosylated with N-acetylglucosamine2-mannose9 units at Asn-Xaa-Ser/Thr sequons during protein synthesis and translocation into the endoplasmic reticulum. These N-glycans are modified in the Golgi machinery, where additional O-glycosylation at Ser and...

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Bibliographic Details

Published in:	Biological chemistry Vol. 395; no. 9; p. 959
Main Authors:	Guo, Shihui, Skala, Wolfgang, Magdolen, Viktor, Brandstetter, Hans, Goettig, Peter
Format:	Journal Article
Language:	English
Published:	Germany 01.09.2014
Subjects:	Amino Acid Sequence Animals Glycoproteins - metabolism Glycosylation Humans Kallikreins - chemistry Kallikreins - metabolism Molecular Sequence Data Polysaccharides - chemistry Polysaccharides - metabolism Substrate Specificity
ISSN:	1437-4315, 1437-4315
Online Access:	Get more information
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