Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?

Bacteraemia caused by Staphylococcus aureus infections can lead to life-threatening metastatic infections. Thwaites and Gant propose that neutrophils form a privileged site that is poorly accessible to antibiotics and that plays an important part in transporting the bacteria to distant sites. Staphy...

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Bibliographic Details
Published in:	Nature reviews. Microbiology Vol. 9; no. 3; pp. 215 - 222
Main Authors:	Thwaites, Guy E., Gant, Vanya
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.03.2011 Nature Publishing Group
Subjects:	631/250/2504/223/1699 631/326/22/1290 631/326/41/2534 692/699/255/1318 Anti-Bacterial Agents - therapeutic use Antibiotics Bacteremia - microbiology Bacteria Bacterial infections Bacterial Proteins - metabolism Biomedical and Life Sciences Catheters Distribution Drug therapy Health aspects Humans Infectious Diseases Leukocytes Leukocytes - microbiology Leukocytes - physiology Life Sciences Medical Microbiology Metastasis Microbiology Neutrophils opinion-2 Parasitology Pathogens Phagocytes - microbiology Prostheses Protection and preservation Risk factors Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity Staphylococcus aureus infections Staphylococcus infections Virology Virulence Virulence Factors - metabolism United Kingdom
ISSN:	1740-1526, 1740-1534, 1740-1534
Online Access:	Get full text
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