NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]-containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...

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Veröffentlicht in:	The Journal of experimental medicine Jg. 213; H. 5; S. 657
Hauptverfasser:	Rauch, Isabella, Tenthorey, Jeannette L, Nichols, Randilea D, Al Moussawi, Khatoun, Kang, James J, Kang, Chulho, Kazmierczak, Barbara I, Vance, Russell E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 02.05.2016
Schlagworte:	Animals Bacteria - genetics Bacteria - immunology Flagellin - genetics Flagellin - immunology Mice Mice, Knockout Neuronal Apoptosis-Inhibitory Protein - genetics Neuronal Apoptosis-Inhibitory Protein - immunology Type III Secretion Systems - genetics Type III Secretion Systems - immunology
ISSN:	1540-9538, 1540-9538
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