Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening

Despite advances in DNA sequencing technology and expanded medical guidelines, the vast majority of individuals carrying pathogenic variants of common cancer susceptibility genes have yet to be identified. An alternative to population-wide genetic screening of healthy individuals would exploit the t...

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Veröffentlicht in:	Journal of clinical oncology Jg. 38; H. 13; S. 1398
Hauptverfasser:	Offit, Kenneth, Tkachuk, Kaitlyn A, Stadler, Zsofia K, Walsh, Michael F, Diaz-Zabala, Hector, Levin, Jeffrey D, Steinsnyder, Zoe, Ravichandran, Vignesh, Sharaf, Ravi N, Frey, Melissa K, Lipkin, Steven M, Robson, Mark E, Hamilton, Jada G, Vijai, Joseph, Mukherjee, Semanti
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.05.2020
Schlagworte:	Adult Early Detection of Cancer - methods Female Genetic Predisposition to Disease - genetics Germ-Line Mutation Humans Linear Models Male Mass Screening - methods Middle Aged Neoplasms - diagnosis Neoplasms - genetics Neoplasms - prevention & control Reproducibility of Results Sensitivity and Specificity United States United States
ISSN:	1527-7755, 1527-7755
Online-Zugang:	Weitere Angaben
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