SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both signature and prognosis of disease severity outcome. Although cytokine storm and a sustained inflammatory state are co...

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Vydané v:	Journal of molecular cell biology Ročník 14; číslo 4
Hlavní autori:	Pontelli, Marjorie C, Castro, Ítalo A, Martins, Ronaldo B, La Serra, Leonardo, Veras, Flávio P, Nascimento, Daniele C, Silva, Camila M, Cardoso, Ricardo S, Rosales, Roberta, Gomes, Rogério, Lima, Thais M, Souza, Juliano P, Vitti, Brenda C, Caetité, Diego B, de Lima, Mikhael H F, Stumpf, Spencer D, Thompson, Cassandra E, Bloyet, Louis-Marie, Toller-Kawahisa, Juliana E, Giannini, Marcela C, Bonjorno, Letícia P, Lopes, Maria I F, Batah, Sabrina S, Siyuan, Li, Luppino-Assad, Rodrigo, Almeida, Sergio C L, Oliveira, Fabiola R, Benatti, Maíra N, Pontes, Lorena L F, Santana, Rodrigo C, Vilar, Fernando C, Auxiliadora-Martins, Maria, Shi, Pei-Yong, Cunha, Thiago M, Calado, Rodrigo T, Alves-Filho, José C, Zamboni, Dario S, Fabro, Alexandre T, Louzada-Junior, Paulo, Oliveira, Rene D R, Whelan, Sean P J, Cunha, Fernando Q, Arruda, Eurico
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Oxford University Press 17.08.2022 Oxford UP
Predmet:	COVID-19 Cytokine Release Syndrome Humans Leukocytes, Mononuclear Life Sciences Microbiology and Parasitology Monocytes SARS-CoV-2 Virology COVID-19 monocytes SARS-CoV-2 lymphocytes apoptosis lymphocytopenia peripheral blood mononuclear cell (PBMC) Tropism Immune cells
ISSN:	1674-2788, 1759-4685, 1759-4685
On-line prístup:	Získať plný text
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