SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both signature and prognosis of disease severity outcome. Although cytokine storm and a sustained inflammatory state are co...

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Bibliographic Details
Published in:	Journal of molecular cell biology Vol. 14; no. 4
Main Authors:	Pontelli, Marjorie C, Castro, Ítalo A, Martins, Ronaldo B, La Serra, Leonardo, Veras, Flávio P, Nascimento, Daniele C, Silva, Camila M, Cardoso, Ricardo S, Rosales, Roberta, Gomes, Rogério, Lima, Thais M, Souza, Juliano P, Vitti, Brenda C, Caetité, Diego B, de Lima, Mikhael H F, Stumpf, Spencer D, Thompson, Cassandra E, Bloyet, Louis-Marie, Toller-Kawahisa, Juliana E, Giannini, Marcela C, Bonjorno, Letícia P, Lopes, Maria I F, Batah, Sabrina S, Siyuan, Li, Luppino-Assad, Rodrigo, Almeida, Sergio C L, Oliveira, Fabiola R, Benatti, Maíra N, Pontes, Lorena L F, Santana, Rodrigo C, Vilar, Fernando C, Auxiliadora-Martins, Maria, Shi, Pei-Yong, Cunha, Thiago M, Calado, Rodrigo T, Alves-Filho, José C, Zamboni, Dario S, Fabro, Alexandre T, Louzada-Junior, Paulo, Oliveira, Rene D R, Whelan, Sean P J, Cunha, Fernando Q, Arruda, Eurico
Format:	Journal Article
Language:	English
Published:	United States Oxford University Press 17.08.2022 Oxford UP
Subjects:	COVID-19 Cytokine Release Syndrome Humans Leukocytes, Mononuclear Life Sciences Microbiology and Parasitology Monocytes SARS-CoV-2 Virology COVID-19 monocytes SARS-CoV-2 lymphocytes apoptosis lymphocytopenia peripheral blood mononuclear cell (PBMC) Tropism Immune cells
ISSN:	1674-2788, 1759-4685, 1759-4685
Online Access:	Get full text
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