Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes

Pandemic live attenuated influenza vaccines (pLAIV) prime subjects for a robust neutralizing antibody response upon subsequent administration of a pandemic inactivated subunit vaccine (pISV). However, a difference was not detected in H5-specific memory B cells in the peripheral blood between pLAIV-p...

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Bibliographic Details
Published in:	Journal of virology Vol. 92; no. 9
Main Authors:	Jegaskanda, Sinthujan, Mason, Rosemarie D, Andrews, Sarah F, Wheatley, Adam K, Zhang, Ruijun, Reynoso, Glennys V, Ambrozak, David R, Santos, Celia P, Luke, Catherine J, Matsuoka, Yumiko, Brenchley, Jason M, Hickman, Heather D, Talaat, Kawsar R, Permar, Sallie R, Liao, Hua-Xin, Yewdell, Jonathan W, Koup, Richard A, Roederer, Mario, McDermott, Adrian B, Subbarao, Kanta
Format:	Journal Article
Language:	English
Published:	United States 01.05.2018
Subjects:	Administration, Intranasal Animals Antibodies, Neutralizing - blood Antibodies, Neutralizing - immunology Antibodies, Viral - blood Antibodies, Viral - immunology B-Lymphocytes - immunology Cercopithecus aethiops Female Humans Influenza A Virus, H5N1 Subtype - immunology Influenza Vaccines - immunology Influenza, Human - prevention & control Lymph Nodes - cytology Lymph Nodes - immunology Lymphocyte Count Male Vaccination Vaccines, Attenuated - immunology Vaccines, Subunit - immunology influenza LAIV B cells vaccines
ISSN:	1098-5514, 1098-5514
Online Access:	Get more information
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