Autologous Transplantation, Consolidation, and Maintenance Therapy in Multiple Myeloma: Results of the BMT CTN 0702 Trial

Single-cycle melphalan 200 mg/m and autologous hematopoietic cell transplantation (AHCT) followed by lenalidomide (len) maintenance have improved progression-free survival (PFS) and overall survival (OS) for transplantation-eligible patients with multiple myeloma (MM). We designed a prospective, ran...

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Veröffentlicht in:	Journal of clinical oncology Jg. 37; H. 7; S. 589
Hauptverfasser:	Stadtmauer, Edward A, Pasquini, Marcelo C, Blackwell, Beth, Hari, Parameswaran, Bashey, Asad, Devine, Steven, Efebera, Yvonne, Ganguly, Siddharta, Gasparetto, Cristina, Geller, Nancy, Horowitz, Mary M, Koreth, John, Knust, Kristin, Landau, Heather, Brunstein, Claudio, McCarthy, Philip, Nelson, Courtney, Qazilbash, Muzaffar H, Shah, Nina, Vesole, David H, Vij, Ravi, Vogl, Dan T, Giralt, Sergio, Somlo, George, Krishnan, Amrita
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2019
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bortezomib - administration & dosage Bortezomib - adverse effects Consolidation Chemotherapy Dexamethasone - administration & dosage Dexamethasone - adverse effects Disease Progression Female Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - mortality Humans Lenalidomide - administration & dosage Lenalidomide - adverse effects Maintenance Chemotherapy Male Melphalan - administration & dosage Middle Aged Multiple Myeloma - mortality Multiple Myeloma - pathology Multiple Myeloma - therapy Myeloablative Agonists - administration & dosage Progression-Free Survival Prospective Studies Remission Induction Reoperation Time Factors Transplantation, Autologous United States Young Adult United States
ISSN:	1527-7755, 1527-7755
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