Oxidative Phosphorylation as an Emerging Target in Cancer Therapy

Cancer cells have upregulated glycolysis compared with normal cells, which has led many to the assumption that oxidative phosphorylation (OXPHOS) is downregulated in all cancers. However, recent studies have shown that OXPHOS can be also upregulated in certain cancers, including leukemias, lymphomas...

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Vydáno v:	Clinical cancer research Ročník 24; číslo 11; s. 2482
Hlavní autoři:	Ashton, Thomas M, McKenna, W Gillies, Kunz-Schughart, Leoni A, Higgins, Geoff S
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.06.2018
Témata:	Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biomarkers Energy Metabolism - drug effects Humans Metabolic Networks and Pathways Mitochondria - drug effects Mitochondria - genetics Mitochondria - metabolism Molecular Targeted Therapy - methods Neoplasms - etiology Neoplasms - metabolism Neoplasms - therapy Oxidative Phosphorylation - drug effects
ISSN:	1557-3265, 1557-3265
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