miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway

miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC. miR-590-3p levels were higher in high-grade carcinoma when compared with...

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Bibliographic Details
Published in:	Cancer research (Chicago, Ill.) Vol. 78; no. 15; p. 4175
Main Authors:	Salem, Mohamed, O'Brien, Jacob A, Bernaudo, Stefanie, Shawer, Heba, Ye, Gang, Brkić, Jelena, Amleh, Asma, Vanderhyden, Barbara C, Refky, Basel, Yang, Burton B, Krylov, Sergey N, Peng, Chun
Format:	Journal Article
Language:	English
Published:	United States 01.08.2018
Subjects:	Carcinoma, Ovarian Epithelial - genetics Carcinoma, Ovarian Epithelial - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Down-Regulation - genetics Female Gene Expression Regulation, Neoplastic - genetics Hepatocyte Nuclear Factor 3-beta - genetics Humans MicroRNAs - genetics Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology RNA, Messenger - genetics Transfection - methods Up-Regulation - genetics Versicans - genetics
ISSN:	1538-7445, 1538-7445
Online Access:	Get more information
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