miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway

miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC. miR-590-3p levels were higher in high-grade carcinoma when compared with...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Jg. 78; H. 15; S. 4175
Hauptverfasser:	Salem, Mohamed, O'Brien, Jacob A, Bernaudo, Stefanie, Shawer, Heba, Ye, Gang, Brkić, Jelena, Amleh, Asma, Vanderhyden, Barbara C, Refky, Basel, Yang, Burton B, Krylov, Sergey N, Peng, Chun
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.08.2018
Schlagworte:	Carcinoma, Ovarian Epithelial - genetics Carcinoma, Ovarian Epithelial - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Down-Regulation - genetics Female Gene Expression Regulation, Neoplastic - genetics Hepatocyte Nuclear Factor 3-beta - genetics Humans MicroRNAs - genetics Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology RNA, Messenger - genetics Transfection - methods Up-Regulation - genetics Versicans - genetics
ISSN:	1538-7445, 1538-7445
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