miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway

miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC. miR-590-3p levels were higher in high-grade carcinoma when compared with...

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Podrobná bibliografie
Vydáno v:	Cancer research (Chicago, Ill.) Ročník 78; číslo 15; s. 4175
Hlavní autoři:	Salem, Mohamed, O'Brien, Jacob A, Bernaudo, Stefanie, Shawer, Heba, Ye, Gang, Brkić, Jelena, Amleh, Asma, Vanderhyden, Barbara C, Refky, Basel, Yang, Burton B, Krylov, Sergey N, Peng, Chun
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.08.2018
Témata:	Carcinoma, Ovarian Epithelial - genetics Carcinoma, Ovarian Epithelial - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Down-Regulation - genetics Female Gene Expression Regulation, Neoplastic - genetics Hepatocyte Nuclear Factor 3-beta - genetics Humans MicroRNAs - genetics Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology RNA, Messenger - genetics Transfection - methods Up-Regulation - genetics Versicans - genetics
ISSN:	1538-7445, 1538-7445
On-line přístup:	Zjistit podrobnosti o přístupu
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