Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies

Bacteria that cause life-threatening infections in humans are becoming increasingly difficult to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance, indicating that new therapeutic approaches are needed to combat bacterial pathogens. There is renewed interest in ut...

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Bibliographic Details
Published in:	Infection and immunity Vol. 88; no. 7
Main Authors:	Mangalea, Mihnea R, Duerkop, Breck A
Format:	Journal Article
Language:	English
Published:	United States 22.06.2020
Subjects:	Animals Anti-Bacterial Agents - pharmacology Bacteria - drug effects Bacteria - virology Bacterial Infections - microbiology Bacterial Infections - therapy Bacterial Physiological Phenomena Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriophages - physiology Cell Membrane - metabolism Drug Resistance, Bacterial Host-Pathogen Interactions Humans Mutation Phage Therapy phage receptor bacterial fitness bacterial infection antibiotic resistance colonization bacteriophages
ISSN:	1098-5522, 1098-5522
Online Access:	Get more information
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