Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices

There is an enduring quest for technologies that provide – temporally and spatially – highly resolved information on electric neuronal or cardiac activity in functional tissues or cell cultures. Here, we present a planar high-density, low-noise microelectrode system realized in microelectronics tech...

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Bibliographic Details
Published in:	Biosensors & bioelectronics Vol. 24; no. 7; pp. 2191 - 2198
Main Authors:	Frey, U., Egert, U., Heer, F., Hafizovic, S., Hierlemann, A.
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier B.V 15.03.2009 Elsevier
Subjects:	Action Potentials - physiology Acute brain slice Animals Biological and medical sciences Biotechnology Cells, Cultured Cerebellum - cytology Cerebellum - physiology CMOS-based microelectrode array Electric Stimulation - methods Fundamental and applied biological sciences. Psychology Humans Integrated circuits Micro-Electrical-Mechanical Systems - instrumentation Microelectrodes Nerve Net - physiology Neurochip Purkinje cells Rats Rats, Long-Evans Integrated circuits Neurochip CMOS-based microelectrode array Purkinje cells Acute brain slice High resolution Microelectronics Extracellular Encephalon Array Electric field Integrated circuit Microelectrode
ISSN:	0956-5663, 1873-4235, 1873-4235
Online Access:	Get full text
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