Conditioned media from (pre)adipocytes stimulate fibrinogen and PAI-1 production by HepG2 hepatoma cells

Background: Obesity is associated with a prothrombotic state, which may contribute to the increased risk of thrombotic events. Objective: To assess the effects of (pre)adipocyte-derived adipokines on fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and tissue factor (TF) production by hepatocyt...

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Bibliographic Details
Published in:Nutrition & diabetes Vol. 2; no. 12; p. e52
Main Authors: Faber, D R, Kalkhoven, E, Westerink, J, Bouwman, J J, Monajemi, H M, Visseren, F L J
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 01.12.2012
Nature Publishing Group
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ISSN:2044-4052, 2044-4052
Online Access:Get full text
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