Earlier surgery improves outcomes from painful chronic pancreatitis

The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a s...

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Vydáno v:	Medicine (Baltimore) Ročník 97; číslo 19; s. e0651
Hlavní autoři:	Ke, Nengwen, Jia, Dan, Huang, Wei, Nunes, Quentin M., Windsor, John A., Liu, Xubao, Sutton, Robert
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved 01.05.2018 Wolters Kluwer Health
Témata:	Abdominal Pain - etiology Abdominal Pain - prevention & control Calcinosis Digestive System Surgical Procedures - adverse effects Digestive System Surgical Procedures - methods Dilatation, Pathologic Female Humans Intraoperative Complications Jaundice - complications Male Middle Aged Observational Study Pancreas - pathology Pancreas - physiology Pancreatic Ducts - pathology Pancreatitis, Chronic - complications Pancreatitis, Chronic - pathology Pancreatitis, Chronic - physiopathology Pancreatitis, Chronic - surgery Postoperative Complications Time Factors
ISSN:	0025-7974, 1536-5964, 1536-5964
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Abstract	The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures.
AbstractList	The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures. The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures.The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures. The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes. Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012. The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/− ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033). Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures.
Author	Ke, Nengwen Windsor, John A. Liu, Xubao Huang, Wei Sutton, Robert Nunes, Quentin M. Jia, Dan
AuthorAffiliation	Department of Pancreatic Surgery Division of General Practice Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK Department of Surgery (JAW), University of Auckland, Auckland, New Zealand
AuthorAffiliation_xml	– name: Department of Pancreatic Surgery Division of General Practice Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK Department of Surgery (JAW), University of Auckland, Auckland, New Zealand – name: c Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China – name: a Department of Pancreatic Surgery – name: d NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK – name: e Department of Surgery (JAW), University of Auckland, Auckland, New Zealand – name: b Division of General Practice
Author_xml	– sequence: 1 givenname: Nengwen surname: Ke fullname: Ke, Nengwen organization: Department of Pancreatic Surgery Division of General Practice Department of Integrated Traditional Chinese and Western Medicine (WH), West China Hospital, Sichuan University, Chengdu, China NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK Department of Surgery (JAW), University of Auckland, Auckland, New Zealand – sequence: 2 givenname: Dan surname: Jia fullname: Jia, Dan – sequence: 3 givenname: Wei surname: Huang fullname: Huang, Wei – sequence: 4 givenname: Quentin surname: Nunes middlename: M. fullname: Nunes, Quentin M. – sequence: 5 givenname: John surname: Windsor middlename: A. fullname: Windsor, John A. – sequence: 6 givenname: Xubao surname: Liu fullname: Liu, Xubao – sequence: 7 givenname: Robert surname: Sutton fullname: Sutton, Robert
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Cites_doi	10.1002/bjs.5722 10.1053/gast.2001.22586 10.1093/jnci/85.5.365 10.1016/j.pan.2015.10.015 10.1097/SLA.0b013e31824b7697 10.1530/ERC-12-0105 10.1038/nrgastro.2014.74 10.1111/jgh.13410 10.1053/j.gastro.2011.07.049 10.1007/s11605-007-0155-6 10.1053/j.gastro.2013.02.008 10.1016/j.pan.2014.11.002 10.1097/SLA.0b013e3182a655a8 10.1016/S0140-6736(16)00141-0 10.1016/j.amjsurg.2014.12.049 10.1007/s00423-010-0731-1 10.1038/nrgastro.2015.166 10.1016/j.pan.2015.01.003 10.1111/j.1365-2036.2009.03931.x 10.1016/S0016-5085(24)05129-1 10.4292/wjgpt.v7.i3.370 10.1016/j.clnu.2014.07.003 10.1111/hpb.12173 10.1056/NEJMoa060610 10.1016/j.pan.2014.09.009 10.1016/S0140-6736(16)00097-0 10.1016/j.pan.2015.05.466 10.1053/j.gastro.2011.04.003 10.1097/MPA.0000000000000333 10.1016/j.surg.2005.05.001 10.1016/j.surg.2012.08.005 10.1007/s11605-015-2928-7 10.1053/j.gastro.2015.08.045 10.1016/j.mayocp.2015.04.010 10.1016/j.jamcollsurg.2014.03.040 10.1097/00000658-199305010-00005 10.1055/s-2003-40237 10.1007/s11605-014-2571-8 10.1080/13651820701481497 10.1186/1471-230X-13-49 10.1097/SLA.0b013e31814a6906 10.1016/j.pan.2016.09.006 10.1097/MPA.0000000000000327
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References	Riediger (R37-24-20210309) 2007; 11 Demir (R27-24-20210309) 2011; 396 Croome (R41-24-20210309) 2015; 19 Olesen (R19-24-20210309) 2011; 141 Lieb (R30-24-20210309) 2009; 29 Ahmed Ali (R36-24-20210309) 2015; 3 Olesen (R7-24-20210309) 2014; 14 Aaronson (R24-24-20210309) 1993; 85 Bachmann (R39-24-20210309) 2014; 219 Ueda (R46-24-20210309) 2013; 153 Issa (R6-24-20210309) 2014; 11 Demir (R28-24-20210309) 2015; 12 Rustagi (R16-24-20210309) 2015; 44 Talukdar (R33-24-20210309) 2015; 15 Forsmark (R5-24-20210309) 2013; 144 D’Haese (R21-24-20210309) 2014; 16 Dite (R9-24-20210309) 2003; 35 Zhou (R17-24-20210309) 2015; 34 Anderson (R4-24-20210309) 2016; 16 Etemad (R22-24-20210309) 2001; 120 Gurusamy (R31-24-20210309) 2016; 2 Ammann (R29-24-20210309) 1984; 86 Mathur (R26-24-20210309) 2007; 246 Yang (R25-24-20210309) 2015; 44 Bachmann (R40-24-20210309) 2013; 258 Shalimar (R18-24-20210309) 2016; 32 Zhou (R48-24-20210309) 2015; 15 Hobbs (R20-24-20210309) 2016; 7 Peery (R3-24-20210309) 2015; 149 van der Gaag (R38-24-20210309) 2012; 255 Ahmed Ali (R32-24-20210309) 2014; 8 Shafiq (R34-24-20210309) 2009; 4 Cahen (R10-24-20210309) 2007; 356 Bassi (R23-24-20210309) 2005; 138 Fischer (R42-24-20210309) 2015; 210 Jamison (R8-24-20210309) 2015; 90 Nealon (R44-24-20210309) 1993; 217 Cui (R45-24-20210309) 2012; 19 Ahmed Ali (R49-24-20210309) 2013; 13 Ahmed Ali (R15-24-20210309) 2014; 8 Teo (R50-24-20210309) 2016; 16 Gurusamy (R47-24-20210309) 2016; 2 Kamisawa (R2-24-20210309) 2016; 388 Yang (R13-24-20210309) 2014; 18 Ahmed Ali (R14-24-20210309) 2012; 147 Majumder (R1-24-20210309) 2016; 387 Cahen (R11-24-20210309) 2011; 141 Lamme (R12-24-20210309) 2007; 94 Ahmed Ali (R35-24-20210309) 2015; 15 Terrace (R43-24-20210309) 2007; 9
References_xml	– volume: 94 start-page: 849 year: 2007 ident: R12-24-20210309 article-title: Early versus late surgical drainage for obstructive pancreatitis in an experimental model publication-title: Br J Surg doi: 10.1002/bjs.5722 – volume: 120 start-page: 682 year: 2001 ident: R22-24-20210309 article-title: Chronic pancreatitis: diagnosis, classification, and new genetic developments publication-title: Gastroenterology doi: 10.1053/gast.2001.22586 – volume: 85 start-page: 365 year: 1993 ident: R24-24-20210309 article-title: The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology publication-title: J Natl Cancer Inst doi: 10.1093/jnci/85.5.365 – volume: 16 start-page: 83 year: 2016 ident: R4-24-20210309 article-title: Mechanism, assessment and management of pain in chronic pancreatitis: recommendations of a multidisciplinary study group publication-title: Pancreatology doi: 10.1016/j.pan.2015.10.015 – volume: 255 start-page: 763 year: 2012 ident: R38-24-20210309 article-title: Functional and medical outcomes after tailored surgery for pain due to chronic pancreatitis publication-title: Ann Surg doi: 10.1097/SLA.0b013e31824b7697 – volume: 19 start-page: F9 year: 2012 ident: R45-24-20210309 article-title: Diabetes and pancreatic cancer publication-title: Endocr Relat Cancer doi: 10.1530/ERC-12-0105 – volume: 11 start-page: 556 year: 2014 ident: R6-24-20210309 article-title: Treatment options for chronic pancreatitis publication-title: Nat Rev Gastroenterol Hepatol doi: 10.1038/nrgastro.2014.74 – volume: 32 start-page: 270 year: 2016 ident: R18-24-20210309 article-title: Long-term pain relief with optimized medical including antioxidants and step-up interventional therapy in patients with chronic pancreatitis publication-title: J Gastroenterol Hepatol doi: 10.1111/jgh.13410 – volume: 141 start-page: 1690 year: 2011 ident: R11-24-20210309 article-title: Long-term outcomes of endoscopic vs surgical drainage of the pancreatic duct in patients with chronic pancreatitis publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.07.049 – volume: 11 start-page: 949 year: 2007 ident: R37-24-20210309 article-title: Long-term outcome after resection for chronic pancreatitis in 224 patients publication-title: J Gastrointest Surg doi: 10.1007/s11605-007-0155-6 – volume: 144 start-page: 1282.e3 year: 2013 ident: R5-24-20210309 article-title: Management of chronic pancreatitis publication-title: Gastroenterology doi: 10.1053/j.gastro.2013.02.008 – volume: 15 start-page: 46 year: 2015 ident: R35-24-20210309 article-title: Dutch Chronic Pancreatitis Registry (CARE): design and rationale of a nationwide prospective evaluation and follow-up publication-title: Pancreatology doi: 10.1016/j.pan.2014.11.002 – volume: 2 start-page: CD011521 year: 2016 ident: R47-24-20210309 article-title: Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis publication-title: Cochrane Database Syst Rev – volume: 258 start-page: 815 year: 2013 ident: R40-24-20210309 article-title: Is the Whipple procedure harmful for long-term outcome in treatment of chronic pancreatitis? 15-years follow-up comparing the outcome after pylorus-preserving pancreatoduodenectomy and Frey procedure in chronic pancreatitis publication-title: Ann Surg doi: 10.1097/SLA.0b013e3182a655a8 – volume: 388 start-page: 73 year: 2016 ident: R2-24-20210309 article-title: Pancreatic cancer publication-title: Lancet doi: 10.1016/S0140-6736(16)00141-0 – volume: 210 start-page: 417 year: 2015 ident: R42-24-20210309 article-title: Local pancreatic head resection: the search for optimal indications through quality of life assessments publication-title: Am J Surg doi: 10.1016/j.amjsurg.2014.12.049 – volume: 396 start-page: 151 year: 2011 ident: R27-24-20210309 article-title: Pain mechanisms in chronic pancreatitis: of a master and his fire publication-title: Langenbecks Arch Surg doi: 10.1007/s00423-010-0731-1 – volume: 12 start-page: 649 year: 2015 ident: R28-24-20210309 article-title: Neural plasticity in pancreatitis and pancreatic cancer publication-title: Nat Rev Gastroenterol Hepatol doi: 10.1038/nrgastro.2015.166 – volume: 15 start-page: 136 year: 2015 ident: R33-24-20210309 article-title: Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis publication-title: Pancreatology doi: 10.1016/j.pan.2015.01.003 – volume: 29 start-page: 706 year: 2009 ident: R30-24-20210309 article-title: Review article: pain and chronic pancreatitis publication-title: Aliment Pharmacol Ther doi: 10.1111/j.1365-2036.2009.03931.x – volume: 86 start-page: 820 year: 1984 ident: R29-24-20210309 article-title: Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients publication-title: Gastroenterology doi: 10.1016/S0016-5085(24)05129-1 – volume: 7 start-page: 370 year: 2016 ident: R20-24-20210309 article-title: Management of pain in chronic pancreatitis with emphasis on exogenous pancreatic enzymes publication-title: World J Gastrointest Pharmacol Ther doi: 10.4292/wjgpt.v7.i3.370 – volume: 34 start-page: 627 year: 2015 ident: R17-24-20210309 article-title: Antioxidant therapy for patients with chronic pancreatitis: A systematic review and meta-analysis publication-title: Clin Nutr doi: 10.1016/j.clnu.2014.07.003 – volume: 16 start-page: 512 year: 2014 ident: R21-24-20210309 article-title: Treatment options in painful chronic pancreatitis: a systematic review publication-title: HPB (Oxford doi: 10.1111/hpb.12173 – volume: 356 start-page: 676 year: 2007 ident: R10-24-20210309 article-title: Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis publication-title: N Engl J Med doi: 10.1056/NEJMoa060610 – volume: 14 start-page: 497 year: 2014 ident: R7-24-20210309 article-title: Pain severity reduces life quality in chronic pancreatitis: implications for design of future outcome trials publication-title: Pancreatology doi: 10.1016/j.pan.2014.09.009 – volume: 387 start-page: 1957 year: 2016 ident: R1-24-20210309 article-title: Chronic pancreatitis publication-title: Lancet doi: 10.1016/S0140-6736(16)00097-0 – volume: 2 start-page: CD011522 year: 2016 ident: R31-24-20210309 article-title: Pregabalin for decreasing pancreatic pain in chronic pancreatitis publication-title: Cochrane Database Syst Rev – volume: 15 start-page: 372 year: 2015 ident: R48-24-20210309 article-title: Frey procedure for chronic pancreatitis: evidence-based assessment of short- and long-term results in comparison to pancreatoduodenectomy and Beger procedure: a meta-analysis publication-title: Pancreatology doi: 10.1016/j.pan.2015.05.466 – volume: 141 start-page: 536 year: 2011 ident: R19-24-20210309 article-title: Pregabalin reduces pain in patients with chronic pancreatitis in a randomized, controlled trial publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.04.003 – volume: 44 start-page: 819 year: 2015 ident: R25-24-20210309 article-title: Surgery for chronic pancreatitis: the role of early surgery in pain management publication-title: Pancreas doi: 10.1097/MPA.0000000000000333 – volume: 8 start-page: CD008945 year: 2014 ident: R32-24-20210309 article-title: Antioxidants for pain in chronic pancreatitis publication-title: Cochrane Database Syst Rev – volume: 138 start-page: 8 year: 2005 ident: R23-24-20210309 article-title: Postoperative pancreatic fistula: an international study group (ISGPF) definition publication-title: Surgery doi: 10.1016/j.surg.2005.05.001 – volume: 8 start-page: CD008945 year: 2014 ident: R15-24-20210309 article-title: Antioxidants for pain in chronic pancreatitis. publication-title: Cochrane Database Syst Rev – volume: 153 start-page: 357 year: 2013 ident: R46-24-20210309 article-title: Research Committee of Intractable Diseases of the P. Surgery for chronic pancreatitis decreases the risk for pancreatic cancer: a multicenter retrospective analysis publication-title: Surgery doi: 10.1016/j.surg.2012.08.005 – volume: 19 start-page: 2146 year: 2015 ident: R41-24-20210309 article-title: Pancreatoduodenectomy for chronic pancreatitis—results of a pain relief and quality of life survey 15 years following operation publication-title: J Gastrointest Surg doi: 10.1007/s11605-015-2928-7 – volume: 149 start-page: 1731 year: 2015 ident: R3-24-20210309 article-title: Burden of gastrointestinal, liver, and pancreatic diseases in the United States publication-title: Gastroenterology doi: 10.1053/j.gastro.2015.08.045 – volume: 90 start-page: 957 year: 2015 ident: R8-24-20210309 article-title: Opioid analgesics publication-title: Mayo Clin Proc doi: 10.1016/j.mayocp.2015.04.010 – volume: 3 start-page: CD007884 year: 2015 ident: R36-24-20210309 article-title: Endoscopic or surgical intervention for painful obstructive chronic pancreatitis publication-title: Cochrane Database Syst Rev – volume: 219 start-page: 208 year: 2014 ident: R39-24-20210309 article-title: Beger and Frey procedures for treatment of chronic pancreatitis: comparison of outcomes at 16-year follow-up publication-title: J Am Coll Surg doi: 10.1016/j.jamcollsurg.2014.03.040 – volume: 217 start-page: 458 year: 1993 ident: R44-24-20210309 article-title: Progressive loss of pancreatic function in chronic pancreatitis is delayed by main pancreatic duct decompression. A longitudinal prospective analysis of the modified puestow procedure publication-title: Ann Surg doi: 10.1097/00000658-199305010-00005 – volume: 35 start-page: 553 year: 2003 ident: R9-24-20210309 article-title: A prospective, randomized trial comparing endoscopic and surgical therapy for chronic pancreatitis publication-title: Endoscopy doi: 10.1055/s-2003-40237 – volume: 18 start-page: 1863 year: 2014 ident: R13-24-20210309 article-title: Systematic review of early surgery for chronic pancreatitis: impact on pain, pancreatic function, and re-intervention publication-title: J Gastrointest Surg doi: 10.1007/s11605-014-2571-8 – volume: 9 start-page: 308 year: 2007 ident: R43-24-20210309 article-title: Results of decompression surgery for pain in chronic pancreatitis publication-title: HPB doi: 10.1080/13651820701481497 – volume: 13 start-page: 49 year: 2013 ident: R49-24-20210309 article-title: Early surgery versus optimal current step-up practice for chronic pancreatitis (ESCAPE): design and rationale of a randomized trial publication-title: BMC Gastroenterol doi: 10.1186/1471-230X-13-49 – volume: 246 start-page: 1058 year: 2007 ident: R26-24-20210309 article-title: Fatty pancreas: a factor in postoperative pancreatic fistula publication-title: Ann Surg doi: 10.1097/SLA.0b013e31814a6906 – volume: 16 start-page: 931 year: 2016 ident: R50-24-20210309 article-title: Pain assessment in chronic pancreatitis: a comparative review of methods publication-title: Pancreatology doi: 10.1016/j.pan.2016.09.006 – volume: 147 start-page: 925 year: 2012 ident: R14-24-20210309 article-title: Clinical outcome in relation to timing of surgery in chronic pancreatitis: a nomogram to predict pain relief publication-title: Arch Surg – volume: 4 start-page: CD006302 year: 2009 ident: R34-24-20210309 article-title: Pancreatic enzymes for chronic pancreatitis. publication-title: Cochrane Database Syst Rev – volume: 44 start-page: 812 year: 2015 ident: R16-24-20210309 article-title: Antioxidant therapy for pain reduction in patients with chronic pancreatitis: a systematic review and meta-analysis publication-title: Pancreas doi: 10.1097/MPA.0000000000000327
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Snippet	The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were... The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes. Clinical course, Izbicki pain scores, and pancreatic function were...
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SubjectTerms	Abdominal Pain - etiology Abdominal Pain - prevention & control Calcinosis Digestive System Surgical Procedures - adverse effects Digestive System Surgical Procedures - methods Dilatation, Pathologic Female Humans Intraoperative Complications Jaundice - complications Male Middle Aged Observational Study Pancreas - pathology Pancreas - physiology Pancreatic Ducts - pathology Pancreatitis, Chronic - complications Pancreatitis, Chronic - pathology Pancreatitis, Chronic - physiopathology Pancreatitis, Chronic - surgery Postoperative Complications Time Factors
Title	Earlier surgery improves outcomes from painful chronic pancreatitis
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