Air pollution and its effects on the immune system
A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vita...
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| Vydáno v: | Free radical biology & medicine Ročník 151; s. 56 - 68 |
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| Hlavní autoři: | , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
Elsevier Inc
01.05.2020
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| Témata: | |
| ISSN: | 0891-5849, 1873-4596, 1873-4596 |
| On-line přístup: | Získat plný text |
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| Abstract | A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vital to understanding how pollution causes disease, and how that pathology could be abrogated.
The immune system itself consists of multiple types of immune cell that act together to generate (or fail to generate) immune responses and in this article we review evidence of how air pollutants can affect different immune cell types such as particle-clearing macrophages, inflammatory neutrophils, dendritic cells that orchestrate adaptive immune responses and lymphocytes that enact those responses. Common themes that emerge are of the capacity of air pollutants to stimulate pro-inflammatory immune responses across multiple classes of immune cell. Air pollution can enhance T helper lymphocyte type 2 (Th2) and T helper lymphocyte type 17 (Th17) adaptive immune responses, as seen in allergy and asthma, and dysregulate anti-viral immune responses. The clinical effects of air pollution, in particular the known association between elevated ambient pollution and exacerbations of asthma and chronic obstructive pulmonary disease (COPD), are consistent with these identified immunological mechanisms. Further to this, as inhaled air pollution deposits primarily on the respiratory mucosa this review focuses on mechanisms of respiratory disease. However, as discussed in the article, air pollution also affects the wider immune system for example in the neonate and gastrointestinal tract. Whilst the many identified actions of air pollution on the immune system are notably diverse, immunological research does suggest potential strategies to ameliorate such effects, for example with vitamin D supplementation. An in-depth understanding of the immunological effects of ambient pollutants should hopefully yield new ideas on how to reduce the adverse health effects of air pollution.
[Display omitted]
•Air pollutants can perturb in vitro anti-microbial and regulatory immune responses.•Pollutants trigger inflammatory cytokine release from the epithelium and macrophages.•Particulates can enhance TH lymphocyte type 2 and 17 responses.•Consistent with the immunology, pollution is clinically associated with respiratory exacerbations.•Strategies such as vitamin D supplementation may ameliorate harmful immune effects. |
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| AbstractList | A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vital to understanding how pollution causes disease, and how that pathology could be abrogated. The immune system itself consists of multiple types of immune cell that act together to generate (or fail to generate) immune responses and in this article we review evidence of how air pollutants can affect different immune cell types such as particle-clearing macrophages, inflammatory neutrophils, dendritic cells that orchestrate adaptive immune responses and lymphocytes that enact those responses. Common themes that emerge are of the capacity of air pollutants to stimulate pro-inflammatory immune responses across multiple classes of immune cell. Air pollution can enhance T helper lymphocyte type 2 (Th2) and T helper lymphocyte type 17 (Th17) adaptive immune responses, as seen in allergy and asthma, and dysregulate anti-viral immune responses. The clinical effects of air pollution, in particular the known association between elevated ambient pollution and exacerbations of asthma and chronic obstructive pulmonary disease (COPD), are consistent with these identified immunological mechanisms. Further to this, as inhaled air pollution deposits primarily on the respiratory mucosa this review focuses on mechanisms of respiratory disease. However, as discussed in the article, air pollution also affects the wider immune system for example in the neonate and gastrointestinal tract. Whilst the many identified actions of air pollution on the immune system are notably diverse, immunological research does suggest potential strategies to ameliorate such effects, for example with vitamin D supplementation. An in-depth understanding of the immunological effects of ambient pollutants should hopefully yield new ideas on how to reduce the adverse health effects of air pollution.A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vital to understanding how pollution causes disease, and how that pathology could be abrogated. The immune system itself consists of multiple types of immune cell that act together to generate (or fail to generate) immune responses and in this article we review evidence of how air pollutants can affect different immune cell types such as particle-clearing macrophages, inflammatory neutrophils, dendritic cells that orchestrate adaptive immune responses and lymphocytes that enact those responses. Common themes that emerge are of the capacity of air pollutants to stimulate pro-inflammatory immune responses across multiple classes of immune cell. Air pollution can enhance T helper lymphocyte type 2 (Th2) and T helper lymphocyte type 17 (Th17) adaptive immune responses, as seen in allergy and asthma, and dysregulate anti-viral immune responses. The clinical effects of air pollution, in particular the known association between elevated ambient pollution and exacerbations of asthma and chronic obstructive pulmonary disease (COPD), are consistent with these identified immunological mechanisms. Further to this, as inhaled air pollution deposits primarily on the respiratory mucosa this review focuses on mechanisms of respiratory disease. However, as discussed in the article, air pollution also affects the wider immune system for example in the neonate and gastrointestinal tract. Whilst the many identified actions of air pollution on the immune system are notably diverse, immunological research does suggest potential strategies to ameliorate such effects, for example with vitamin D supplementation. An in-depth understanding of the immunological effects of ambient pollutants should hopefully yield new ideas on how to reduce the adverse health effects of air pollution. A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vital to understanding how pollution causes disease, and how that pathology could be abrogated. The immune system itself consists of multiple types of immune cell that act together to generate (or fail to generate) immune responses and in this article we review evidence of how air pollutants can affect different immune cell types such as particle-clearing macrophages, inflammatory neutrophils, dendritic cells that orchestrate adaptive immune responses and lymphocytes that enact those responses. Common themes that emerge are of the capacity of air pollutants to stimulate pro-inflammatory immune responses across multiple classes of immune cell. Air pollution can enhance T helper lymphocyte type 2 (Th2) and T helper lymphocyte type 17 (Th17) adaptive immune responses, as seen in allergy and asthma, and dysregulate anti-viral immune responses. The clinical effects of air pollution, in particular the known association between elevated ambient pollution and exacerbations of asthma and chronic obstructive pulmonary disease (COPD), are consistent with these identified immunological mechanisms. Further to this, as inhaled air pollution deposits primarily on the respiratory mucosa this review focuses on mechanisms of respiratory disease. However, as discussed in the article, air pollution also affects the wider immune system for example in the neonate and gastrointestinal tract. Whilst the many identified actions of air pollution on the immune system are notably diverse, immunological research does suggest potential strategies to ameliorate such effects, for example with vitamin D supplementation. An in-depth understanding of the immunological effects of ambient pollutants should hopefully yield new ideas on how to reduce the adverse health effects of air pollution. A well-functioning immune system is vital for a healthy body. Inadequate and excessive immune responses underlie diverse pathologies such as serious infections, metastatic malignancies and auto-immune conditions. Therefore, understanding the effects of ambient pollutants on the immune system is vital to understanding how pollution causes disease, and how that pathology could be abrogated. The immune system itself consists of multiple types of immune cell that act together to generate (or fail to generate) immune responses and in this article we review evidence of how air pollutants can affect different immune cell types such as particle-clearing macrophages, inflammatory neutrophils, dendritic cells that orchestrate adaptive immune responses and lymphocytes that enact those responses. Common themes that emerge are of the capacity of air pollutants to stimulate pro-inflammatory immune responses across multiple classes of immune cell. Air pollution can enhance T helper lymphocyte type 2 (Th2) and T helper lymphocyte type 17 (Th17) adaptive immune responses, as seen in allergy and asthma, and dysregulate anti-viral immune responses. The clinical effects of air pollution, in particular the known association between elevated ambient pollution and exacerbations of asthma and chronic obstructive pulmonary disease (COPD), are consistent with these identified immunological mechanisms. Further to this, as inhaled air pollution deposits primarily on the respiratory mucosa this review focuses on mechanisms of respiratory disease. However, as discussed in the article, air pollution also affects the wider immune system for example in the neonate and gastrointestinal tract. Whilst the many identified actions of air pollution on the immune system are notably diverse, immunological research does suggest potential strategies to ameliorate such effects, for example with vitamin D supplementation. An in-depth understanding of the immunological effects of ambient pollutants should hopefully yield new ideas on how to reduce the adverse health effects of air pollution. [Display omitted] •Air pollutants can perturb in vitro anti-microbial and regulatory immune responses.•Pollutants trigger inflammatory cytokine release from the epithelium and macrophages.•Particulates can enhance TH lymphocyte type 2 and 17 responses.•Consistent with the immunology, pollution is clinically associated with respiratory exacerbations.•Strategies such as vitamin D supplementation may ameliorate harmful immune effects. |
| Author | Pfeffer, Paul E. Ho, Tzer-Ren Camiña, Nuria Hawrylowicz, Catherine M. Glencross, Drew A. |
| Author_xml | – sequence: 1 givenname: Drew A. surname: Glencross fullname: Glencross, Drew A. organization: Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, SE1 9RT, UK – sequence: 2 givenname: Tzer-Ren surname: Ho fullname: Ho, Tzer-Ren organization: Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, SE1 9RT, UK – sequence: 3 givenname: Nuria surname: Camiña fullname: Camiña, Nuria organization: MRC Centre for Environment and Health, King's College London, Franklin Wilkins Building, London, SE1 9NH, UK – sequence: 4 givenname: Catherine M. surname: Hawrylowicz fullname: Hawrylowicz, Catherine M. email: catherine.hawrylowicz@kcl.ac.uk organization: Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, SE1 9RT, UK – sequence: 5 givenname: Paul E. surname: Pfeffer fullname: Pfeffer, Paul E. organization: Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32007522$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1183/09031936.96.09112298 10.1016/j.envres.2018.08.019 10.1161/01.CIR.0000013838.94747.64 10.1164/rccm.201807-1206ED 10.1016/j.envint.2016.11.012 10.1289/ehp.0901461 10.1164/ajrccm.164.5.2010160 10.1016/j.jaci.2011.11.033 10.1046/j.1365-2567.1996.d01-687.x 10.1126/science.1078231 10.1016/S2468-2667(18)30202-0 10.1016/j.jaci.2013.06.048 10.1039/c2cs35076a 10.1016/j.envres.2017.10.041 10.1164/ajrccm.161.2.9905052 10.2147/COPD.S122282 10.1016/j.chemosphere.2014.10.039 10.1165/rcmb.2016-0409OC 10.1016/j.envpol.2018.05.055 10.1165/rcmb.2009-0427OC 10.1016/j.envint.2014.09.010 10.1159/000161584 10.1056/NEJMoa071535 10.1016/j.immuni.2018.09.015 10.1016/j.vaccine.2010.09.033 10.1371/journal.pone.0062220 10.1021/acs.biochem.5b00308 10.1056/NEJMoa052972 10.1182/blood-2012-08-453597 10.1007/s11356-017-9995-0 10.1016/j.envres.2019.108567 10.1165/ajrcmb/9.3.271 10.1067/mai.2000.110154 10.1021/acs.chemrestox.6b00326 10.1371/journal.pone.0138146 10.1186/1465-9921-6-87 10.1289/ehp.7339 10.1111/all.13462 10.1146/annurev.pharmtox.46.120604.141046 10.1172/JCI117478 10.1164/rccm.2111021 10.1016/j.taap.2004.07.007 10.1146/annurev-immunol-032713-120245 10.1038/nature06881 10.1126/scitranslmed.aab3142 10.1056/NEJMoa1414123 10.1002/ibd.21455 10.1080/08958370601052121 10.1016/j.rmed.2011.09.007 10.1016/j.jaci.2007.01.016 10.1189/jlb.1008587 10.1164/ajrccm.155.4.9105091 10.1183/09031936.93.06091308 10.3109/1547691X.2011.629638 10.1016/j.immuni.2018.07.010 10.1038/mi.2012.74 10.1007/s00418-009-0565-5 10.1161/01.CIR.0000142053.13921.21 10.1016/j.redox.2014.05.004 10.1111/pce.12601 10.1164/rccm.201408-1568LE 10.1289/ehp.1306770 10.1165/rcmb.2007-0199OC 10.2217/nnm.15.2 10.1164/rccm.201712-2506OC 10.1164/ajrccm.159.3.9709083 10.1098/rstb.2014.0049 10.1016/j.scitotenv.2017.04.206 10.1016/j.jaci.2015.01.026 10.1136/adc.73.5.418 10.1164/rccm.201904-0834ED 10.2147/COPD.S136592 10.1164/ajrccm.164.5.2008003 10.1016/0092-8674(89)90688-0 10.1016/j.freeradbiomed.2012.11.006 10.1097/EDE.0000000000000732 10.1016/j.nano.2015.12.369 10.1371/journal.pone.0200040 10.1189/jlb.0313153 10.1289/ehp.0900550 10.1073/pnas.95.6.3071 10.1186/1743-8977-8-19 10.3389/fimmu.2017.01781 10.1164/rccm.201406-1039OC 10.1016/j.atmosenv.2012.06.039 10.1136/oemed-2012-100993 10.1183/09031936.00036709 10.1038/nature06880 10.1080/10937404.2012.632359 10.1164/rccm.201504-0658OC 10.1126/scitranslmed.aaa0282 10.1080/08958370802603789 10.1165/rcmb.2015-0084OC 10.1038/s41467-019-11654-3 10.1016/j.tiv.2010.08.017 10.1016/0272-0590(88)90284-9 10.1038/ajg.2010.252 10.1165/rcmb.2016-0351OC 10.1164/rccm.201104-0597OC 10.1111/all.12627 10.1093/aje/153.11.1031 10.1007/s10875-007-9149-0 10.1016/S0140-6736(99)01812-7 10.1016/j.jaci.2010.08.008 10.3233/JAD-170012 10.1164/ajrccm.159.2.9711068 10.1164/rccm.201809-1657OC 10.4049/jimmunol.176.12.7431 10.1111/imm.12852 10.1016/j.jaci.2017.05.010 10.1164/rccm.201712-2526OC 10.1007/s13181-011-0203-1 10.1172/JCI30639 10.1164/rccm.201603-0451OC 10.1016/j.immuni.2014.06.008 10.1016/j.jaci.2017.04.038 10.1016/j.rmed.2006.11.010 10.1136/oemed-2012-100864 10.1165/ajrcmb.27.1.4787 10.1016/j.envres.2015.09.032 10.1289/ehp.0900916 10.1513/pats.200808-092RM 10.1016/j.immuni.2013.08.003 10.1042/bj3250095 10.1136/oem.60.11.892 10.1183/09031936.96.09020334 10.1080/08958370801903784 10.1371/journal.pone.0174050 10.1016/j.chest.2017.09.005 10.1038/nri.2017.54 10.1016/j.clim.2003.08.006 10.1016/S0140-6736(10)61380-3 10.1186/1471-2393-11-87 10.1152/ajpcell.1998.275.1.C1 10.1371/journal.pone.0016200 10.1136/oem.2004.014332 10.1016/j.envres.2016.08.018 10.1016/j.immuni.2016.10.026 10.1111/cea.13261 10.1021/es301431s 10.1038/nri1733 10.1165/rcmb.2012-0465OC 10.1590/S0100-879X2005000700003 10.1152/ajplung.00162.2006 10.1016/j.bbrc.2008.09.038 10.1097/00001648-200407000-00160 |
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| References | Chambers, Nanzer, Pfeffer, Richards, Timms, Martineau, Griffiths, Corrigan, Hawrylowicz (bib79) 2015; 136 Stockinger, Di Meglio, Gialitakis, Duarte (bib19) 2014; 32 Eggleton, Nissim, Ryan, Whiteman, Winyard (bib104) 2013; 57 Khreis, Kelly, Tate, Parslow, Lucas, Nieuwenhuijsen (bib109) 2017; 100 Mann, Ho, Pfeffer, Matthews, Chevretton, Mudway, Kelly, Hawrylowicz (bib69) 2017; 57 Ramanathan, London, Tharakan, Surya, Sussan, Rao, Lin, Toskala, Rajagopalan, Biswal (bib93) 2017; 57 Kourie (bib14) 1998; 275 Bove, Bongaerts, Slenders, Bijnens, Saenen, Gyselaers, Van Eyken, Plusquin, Roeffaers, Ameloot, Nawrot (bib124) 2019; 10 Janssen, de Meer, Brunekreef (bib92) 2004; 15 Hemming, Hughes, Rennie, Tomas, Campbell, Hughes, Arnold, Botchway, Thompson (bib105) 2015; 54 Zhao, Elkelish, Durner, Lindermayr, Winkler, Rusmall io, Behrendt, Traidl-Hoffmann, Holzinger, Kofler, Braun, von Toerne, Hauck, Ernst, Frank (bib108) 2016; 39 Ayyagari, Januszkiewicz, Nath (bib112) 2007; 19 Kaplan, Hubbard, Korzenik, Sands, Panaccione, Ghosh, Wheeler, Villeneuve (bib141) 2010; 105 Fujii, Hayashi, Hogg, Mukae, Suwa, Goto, Vincent, van Eeden (bib26) 2002; 27 Bleck, Tse, Jaspers, Curotto de Lafaille, Reibman (bib66) 2006; 176 Fraternale, Paoletti, Dominici, Caputo, Castaldello, Millo, Brocca-Cofano, Smietana, Clayette, Oiry, Benatti, Magnani (bib62) 2010; 28 Balhara, Gounni (bib114) 2012; 5 Mutlu, Engen, Soberanes, Urich, Forsyth, Nigdelioglu, Chiarella, Radigan, Gonzalez, Jakate, Keshavarzian, Budinger, Mutlu (bib142) 2011; 8 van der Vliet, O'Neill, Cross, Koostra, Volz, Halliwell, Louie (bib30) 1999; 276 Ananthakrishnan, McGinley, Binion, Saeian (bib140) 2011; 17 Jacobs, Emmerechts, Hoylaerts, Mathieu, Hoet, Nemery, Nawrot (bib55) 2011; 6 Li, Sun, Tang, Qiu, Huang, Mason, Tian (bib118) 2016; 11 Veldhoen, Hirota, Westendorf, Buer, Dumoutier, Renauld, Stockinger (bib144) 2008; 453 Rahman, MacNee (bib35) 1999; 277 Kowalska, Wegierek-Ciuk, Brzoska, Wojewodzka, Meczynska-Wielgosz, Gromadzka-Ostrowska, Mruk, Ovrevik, Kruszewski, Lankoff (bib21) 2017; 24 Bosson, Mudway, Sandstrom (bib6) 2019; 200 van Eeden, Tan, Suwa, Mukae, Terashima, Fujii, Qui, Vincent, Hogg (bib145) 2001; 164 Zhou, Tung, Tsai, Hsu, Chang, Kawasaki, Tseng, Plunkett, Gao, Hung, Vonakis, Huang (bib96) 2013; 121 Calderon-Garciduenas, Gonzalez-Maciel, Mukherjee, Reynoso-Robles, Perez-Guille, Gayosso-Chavez, Torres-Jardon, Cross, Ahmed, Karloukovski, Maher (bib149) 2019; 176 Brook, Brook, Urch, Vincent, Rajagopalan, Silverman (bib146) 2002; 105 Nemmar, Hoet, Vermylen, Nemery, Hoylaerts (bib95) 2004; 110 Rusznak, Devalia, Sapsford, Davies (bib51) 1996; 9 Martinez (bib123) 2019; 39 Zelante, Iannitti, Cunha, De Luca, Giovannini, Pieraccini, Zecchi, D'Angelo, Massi-Benedetti, Fallarino, Carvalho, Puccetti, Romani (bib22) 2013; 39 O'Beirne, Shenoy, Salit, Strulovici-Barel, Kaner, Visvanathan, Fine, Mezey, Crystal (bib151) 2018; 198 Gehring, Gruzieva, Agius, Beelen, Custovic, Cyrys, Eeftens, Flexeder, Fuertes, Heinrich, Hoffmann, de Jongste, Kerkhof, Klumper, Korek, Molter, Schultz, Simpson, Sugiri, Svartengren, von Berg, Wijga, Pershagen, Brunekreef (bib135) 2013; 121 Matthews, Pfeffer, Mann, Kelly, Corrigan, Hawrylowicz, Lee (bib68) 2015; 54 Salvi, Nordenhall, Blomberg, Rudell, Pourazar, Kelly, Wilson, Sandstrom, Holgate, Frew (bib87) 2000; 161 Bertazzi, Consonni, Bachetti, Rubagotti, Baccarelli, Zocchetti, Pesatori (bib18) 2001; 153 Murray, Allen, Biswas, Fisher, Gilroy, Goerdt, Gordon, Hamilton, Ivashkiv, Lawrence, Locati, Mantovani, Martinez, Mege, Mosser, Natoli, Saeij, Schultze, Shirey, Sica, Suttles, Udalova, van Ginderachter, Vogel, Wynn (bib58) 2014; 41 Busse, Lemanske, Gern (bib111) 2010; 376 Rosser, Brehm, Forno, Acosta-Perez, Kurland, Canino, Celedon (bib153) 2014; 190 Ghio, Carraway, Madden (bib4) 2012; 15 Shoenfelt, Mitkus, Zeisler, Spatz, Powell, Fenton, Squibb, Medvedev (bib10) 2009; 86 Elahi, Matata (bib59) 2008; 376 Taylor, Finney-Hayward, Quint, Thomas, Tudhope, Wedzicha, Barnes, Donnelly (bib113) 2010; 35 Devalia, Sapsford, Cundell, Rusznak, Campbell, Davies (bib49) 1993; 6 Bharadwaj, Zivin, Mullins, Neidell (bib126) 2016; 194 Behndig, Blomberg, Helleday, Duggan, Kelly, Mudway (bib31) 2009; 21 Brown, Wyatt, Price, Kelly (bib36) 1996; 9 Zhang, Zhivaki, Lo-Man (bib131) 2017; 17 Brandt, Kovacic, Lee, Gibson, Acciani, Le Cras, Ryan, Budelsky, Khurana Hershey (bib71) 2013; 132 Thompson, Zanobetti, Silverman, Schwartz, Coull, Urch, Speck, Brook, Manno, Gold (bib41) 2010; 118 Salvi, Blomberg, Rudell, Kelly, Sandstrom, Holgate, Frew (bib86) 1999; 159 Li, Bostick, Ye, Qiu, Zhang, Urban, Avram, Zhou (bib77) 2018; 49 Kelly, Mudway, Blomberg, Frew, Sandstrom (bib8) 1999; 354 Pasare, Medzhitov (bib100) 2003; 299 Mutlu, Green, Bellmeyer, Baker, Burgess, Rajamannan, Christman, Foiles, Kamp, Ghio, Chandel, Dean, Sznajder, Budinger (bib42) 2007; 117 Becher, Tugues, Greter (bib39) 2016; 45 Pfeffer, Donaldson, Mackay, Wedzicha (bib122) 2019; 199 Mortaz, Barnes, Heidarnazhad, Adcock, Masjedi (bib99) 2012; 11 Ryan, Nissim, Winyard (bib103) 2014; 2 Deng, Lu, Norback, Bornehag, Zhang, Liu, Yuan, Sundell (bib130) 2015; 143 McKenzie, Kendall, Mackay, Tetley, Morgan, Griffiths, Clark, Madsen (bib38) 2015; 370 Bosson, Pourazar, Forsberg, Adelroth, Sandstrom, Blomberg (bib88) 2007; 101 Mudway, Dundas, Wood, Marlin, Jamaludin, Bremner, Cross, Grieve, Nanzer, Barratt, Beevers, Dajnak, Fuller, Font, Colligan, Sheikh, Walton, Grigg, Kelly, Lee, Griffiths (bib134) 2019; 4 Gauderman, Gilliland, Vora, Avol, Stram, McConnell, Thomas, Lurmann, Margolis, Rappaport, Berhane, Peters (bib136) 2002; 166 Lichtveld, Ebersviller, Sexton, Vizuete, Jaspers, Jeffries (bib28) 2012; 46 Castaneda, Vogel, Bein, Hughes, Smiley-Jewell, Pinkerton (bib81) 2018; 6 Amin (bib94) 2012; 106 Bleck, Tse, Curotto de Lafaille, Zhang, Reibman (bib67) 2008; 28 Samet, Hatch, Horstman, Steck-Scott, Arab, Bromberg, Levine, McDonnell, Devlin (bib32) 2001; 164 Seaton, Cherrie, Dennekamp, Donaldson, Hurley, Tran (bib84) 2005; 62 Becker, Dailey, Soukup, Silbajoris, Devlin (bib11) 2005; 203 Metidji, Omenetti, Crotta, Li, Nye, Ross, Li, Maradana, Schiering, Stockinger (bib76) 2018; 49 Burbank, Sood, Kesic, Peden, Hernandez (bib125) 2017; 140 Jackson, Makrinioti, Rana, Shamji, Trujillo-Torralbo, Footitt, Jerico, Telcian, Nikonova, Zhu, Aniscenko, Gogsadze, Bakhsoliani, Traub, Dhariwal, Porter, Hunt, Hunt, Hunt, Stanciu, Khaitov, Bartlett, Edwards, Kon, Mallia, Papadopoulos, Akdis, Westwick, Edwards, Cousins, Walton, Johnston (bib116) 2014; 190 Zheng, Ding, Jiang, Chen, Zheng, Qiu, Zhou, Chen, Guan (bib120) 2015; 10 Kelly, Fussel (bib85) 2012; 60 Contoli, Ito, Padovani, Poletti, Marku, Edwards, Stanciu, Gnesini, Pastore, Spanevello, Morelli, Johnston, Caramori, Papi (bib115) 2015; 70 Baiz, Slama, Bene, Charles, Kolopp-Sarda, Magnan, Thiebaugeorges, Faure, Annesi-Maesano (bib132) 2011; 11 Kim, Barajas, Chan, Nel (bib60) 2007; 119 Terashima, Wiggs, English, Hogg, van Eeden (bib52) 1997; 155 Kumar, Forbes, Mudway, Bicer, Dailey (bib29) 2015; 10 Zhao, Gao, Tian, Xie, Xin, Jiang, Kan, Song (bib80) 2013; 70 Yarova, Stewart, Sathish, Britt, Thompson, AP, Freeman, Aravamudan, Kita, Brennan, Schepelmann, Davies, Yung, Cholisoh, Kidd, Ford, Broadley, Rietdorf, Chang, Bin Khayat, Ward, Corrigan, JP, Kemp, Pabelick, Prakash, Riccardi (bib16) 2015; 7 Gauderman, Urman, Avol, Berhane, McConnell, Rappaport, Chang, Lurmann, Gilliland (bib137) 2015; 372 Anderson, Thundiyil, Stolbach (bib1) 2012; 8 Bai, Brugha, Jacobs, Grigg, Nawrot, Nemery (bib53) 2015; 74 Pfeffer, Ho, Mann, Kelly, Sehlstedt, Pourazar, Dove, Sandstrom, Mudway, Hawrylowicz (bib65) 2017; 153 Heal, Kumar, Harrison (bib3) 2012; 41 Martinez (bib138) 2009; 6 Kish, Hotte, Kaplan, Vincent, Tso, Ganzle, Rioux, Thiesen, Barkema, Wine, Madsen (bib143) 2013; 8 Nakamura, Inoue, Fujitani, Kiyono, Hirano, Takano (bib74) 2012; 9 McCreanor, Cullinan, Nieuwenhuijsen, Stewart-Evans, Malliarou, Jarup, Harrington, Svartengren, Han, Ohman-Strickland, Chung, Zhang (bib89) 2007; 357 Matsuzaki, Okamoto, Sarashina, Ito, Togawa, Saito (bib48) 1996; 88 Orellano, Quaranta, Reynoso, Balbi, Vasquez (bib119) 2017; 12 Kido, Tamagawa, Bai, Suda, Yang, Li, Chiang, Yatera, Mukae, Sin, Van Eeden (bib40) 2011; 44 Peterson, Herzenberg, Vasquez, Waltenbaugh (bib61) 1998; 95 Pathmanathan, Krishna, Blomberg, Helleday, Kelly, Sandstrom, Holgate, Wilson, Frew (bib46) 2002; 60 Morrow (bib54) 1988; 10 Blomberg, Krishna, Helleday, Soderberg, Ledin, Kelly, Frew, Holgate, Sandstrom (bib90) 1999; 159 Scandalios (bib12) 2005; 38 Ishii, Hayashi, Hogg, Fujii, Goto, Sakamoto, Mukae, Vincent, van Eeden (bib27) 2005; 6 Steenhof, Mudway, Gosens, Hoek, Godri, Kelly, Harrison, Pieters, Cassee, Lebret, Brunekreef, Strak, Janssen (bib34) 2013; 70 Bose, Rosa, Mathilda Chiu, Leon Hsu, Di, Lee, Kloog, Wilson, Schwartz, Wright, Morgan, Coull, Wright (bib128) 2018; 167 Weng, Wang, Lee, He, Huang, Chao, Chung, Kuo (bib43) 2018; 73 Mitschik, Schierl, Nowak, Jorres (bib24) 2008; 20 Brown, Hutchison, Donaldson, Stone (bib15) 2007; 292 Pfeffer, Hawrylowicz (bib152) 2017; 153 Kensler, Wakabayashi, Biswal (bib13) 2007; 47 Ribeiro, Costa, Abreu, Esteves da Silva (bib107) 2017; 599–600 Wooding, Ryu, Huls, Lee, Lin, Rider, Yuen, Carlsten (bib5) 2019; 200 Hirota, Hirota, Warner, Stefanowicz, Shaheen, Beck, Macdonald, Hackett, Sin, Van Eeden, Knight (bib17) 2012; 129 Lin, Lore (bib97) 2017; 8 Gour, Sudini, Khalil, Rule, Lees, Gabrielson, Groopman, Lajoie, Singh (bib72) 2018; 161 de Barros Mendes Lopes, Groth, Veras, Furuya, de Souza Xavier Costa, Ribeiro Junior, Lopes, de Almeida, Cardoso, Saldiva, Chammas, Mauad (bib139) 2018; 241 Greve, Davis, Meyer, Forte, Yost, Marlor, Kamarck, McClelland (bib47) 1989; 56 Matthews, Faith, Pfeffer, Lu, Kelly, Hawrylowicz (bib64) 2014; 50 Edgar, Stephens, Doerr, Scott (bib7) 1955; 48 Pfeffer, Mudway (bib150) 2018; 198 Kumagai, Abiko (bib106) 2017; 30 Gonzalez-Maciel, Reynoso-Robles, Torres-Jardon, Mukherjee, Calderon-Garciduenas (bib148) 2017; 59 Goldstein, Peek, Parks, Hines, Steffey, Tarkington (bib50) 1977; 115 Kim, Chen, Zhou, Huang (bib133) 2018; 4 Sau Peterson (10.1016/j.freeradbiomed.2020.01.179_bib61) 1998; 95 Stockinger (10.1016/j.freeradbiomed.2020.01.179_bib19) 2014; 32 Kulkarni (10.1016/j.freeradbiomed.2020.01.179_bib56) 2006; 355 Martinez (10.1016/j.freeradbiomed.2020.01.179_bib138) 2009; 6 Diaz-Sanchez (10.1016/j.freeradbiomed.2020.01.179_bib82) 1994; 94 Nemmar (10.1016/j.freeradbiomed.2020.01.179_bib95) 2004; 110 Taylor (10.1016/j.freeradbiomed.2020.01.179_bib113) 2010; 35 Kish (10.1016/j.freeradbiomed.2020.01.179_bib143) 2013; 8 Bertazzi (10.1016/j.freeradbiomed.2020.01.179_bib18) 2001; 153 Gour (10.1016/j.freeradbiomed.2020.01.179_bib72) 2018; 161 Greve (10.1016/j.freeradbiomed.2020.01.179_bib47) 1989; 56 Li (10.1016/j.freeradbiomed.2020.01.179_bib25) 2003; 109 Bosson (10.1016/j.freeradbiomed.2020.01.179_bib88) 2007; 101 Brown (10.1016/j.freeradbiomed.2020.01.179_bib36) 1996; 9 Bleck (10.1016/j.freeradbiomed.2020.01.179_bib67) 2008; 28 Pasare (10.1016/j.freeradbiomed.2020.01.179_bib100) 2003; 299 Kumar (10.1016/j.freeradbiomed.2020.01.179_bib29) 2015; 10 Gordon (10.1016/j.freeradbiomed.2020.01.179_bib57) 2005; 5 Veldhoen (10.1016/j.freeradbiomed.2020.01.179_bib144) 2008; 453 Quintana (10.1016/j.freeradbiomed.2020.01.179_bib23) 2008; 453 Mitschik (10.1016/j.freeradbiomed.2020.01.179_bib24) 2008; 20 Thompson (10.1016/j.freeradbiomed.2020.01.179_bib41) 2010; 118 Metidji (10.1016/j.freeradbiomed.2020.01.179_bib76) 2018; 49 Soyseth (10.1016/j.freeradbiomed.2020.01.179_bib91) 1995; 73 Jung (10.1016/j.freeradbiomed.2020.01.179_bib110) 2017; 28 de Barros Mendes Lopes (10.1016/j.freeradbiomed.2020.01.179_bib139) 2018; 241 Hemming (10.1016/j.freeradbiomed.2020.01.179_bib105) 2015; 54 Deng (10.1016/j.freeradbiomed.2020.01.179_bib130) 2015; 143 Gauderman (10.1016/j.freeradbiomed.2020.01.179_bib137) 2015; 372 Brook (10.1016/j.freeradbiomed.2020.01.179_bib146) 2002; 105 Rosser (10.1016/j.freeradbiomed.2020.01.179_bib153) 2014; 190 Ghio (10.1016/j.freeradbiomed.2020.01.179_bib4) 2012; 15 Anderson (10.1016/j.freeradbiomed.2020.01.179_bib1) 2012; 8 Rusznak (10.1016/j.freeradbiomed.2020.01.179_bib51) 1996; 9 Ji (10.1016/j.freeradbiomed.2020.01.179_bib75) 2015; 120 Fujii (10.1016/j.freeradbiomed.2020.01.179_bib26) 2002; 27 Nakamura (10.1016/j.freeradbiomed.2020.01.179_bib74) 2012; 9 Orellano (10.1016/j.freeradbiomed.2020.01.179_bib119) 2017; 12 Muralidharan (10.1016/j.freeradbiomed.2020.01.179_bib9) 2013; 94 Balhara (10.1016/j.freeradbiomed.2020.01.179_bib114) 2012; 5 Pfeffer (10.1016/j.freeradbiomed.2020.01.179_bib152) 2017; 153 Kaplan (10.1016/j.freeradbiomed.2020.01.179_bib141) 2010; 105 Calderon-Garciduenas (10.1016/j.freeradbiomed.2020.01.179_bib149) 2019; 176 Seaton (10.1016/j.freeradbiomed.2020.01.179_bib84) 2005; 62 Kourie (10.1016/j.freeradbiomed.2020.01.179_bib14) 1998; 275 McKenzie (10.1016/j.freeradbiomed.2020.01.179_bib38) 2015; 370 Pfeffer (10.1016/j.freeradbiomed.2020.01.179_bib65) 2017; 153 Kensler (10.1016/j.freeradbiomed.2020.01.179_bib13) 2007; 47 Kelly (10.1016/j.freeradbiomed.2020.01.179_bib85) 2012; 60 Pfeffer (10.1016/j.freeradbiomed.2020.01.179_bib150) 2018; 198 Ramanathan (10.1016/j.freeradbiomed.2020.01.179_bib93) 2017; 57 Devalia (10.1016/j.freeradbiomed.2020.01.179_bib49) 1993; 6 den Hartigh (10.1016/j.freeradbiomed.2020.01.179_bib20) 2010; 24 Mudway (10.1016/j.freeradbiomed.2020.01.179_bib134) 2019; 4 Li (10.1016/j.freeradbiomed.2020.01.179_bib77) 2018; 49 Burbank (10.1016/j.freeradbiomed.2020.01.179_bib125) 2017; 140 Behndig (10.1016/j.freeradbiomed.2020.01.179_bib31) 2009; 21 Morrow (10.1016/j.freeradbiomed.2020.01.179_bib54) 1988; 10 Shoenfelt (10.1016/j.freeradbiomed.2020.01.179_bib10) 2009; 86 Kelly (10.1016/j.freeradbiomed.2020.01.179_bib8) 1999; 354 Khreis (10.1016/j.freeradbiomed.2020.01.179_bib109) 2017; 100 Gauderman (10.1016/j.freeradbiomed.2020.01.179_bib136) 2002; 166 Ryan (10.1016/j.freeradbiomed.2020.01.179_bib103) 2014; 2 Bleck (10.1016/j.freeradbiomed.2020.01.179_bib66) 2006; 176 Kido (10.1016/j.freeradbiomed.2020.01.179_bib40) 2011; 44 Kim (10.1016/j.freeradbiomed.2020.01.179_bib60) 2007; 119 Matthews (10.1016/j.freeradbiomed.2020.01.179_bib64) 2014; 50 Matsuzaki (10.1016/j.freeradbiomed.2020.01.179_bib48) 1996; 88 Robinson (10.1016/j.freeradbiomed.2020.01.179_bib83) 2009; 131 Li (10.1016/j.freeradbiomed.2020.01.179_bib118) 2016; 11 Weng (10.1016/j.freeradbiomed.2020.01.179_bib43) 2018; 73 Bove (10.1016/j.freeradbiomed.2020.01.179_bib124) 2019; 10 Ananthakrishnan (10.1016/j.freeradbiomed.2020.01.179_bib140) 2011; 17 Jacobs (10.1016/j.freeradbiomed.2020.01.179_bib55) 2011; 6 Brandt (10.1016/j.freeradbiomed.2020.01.179_bib71) 2013; 132 Amin (10.1016/j.freeradbiomed.2020.01.179_bib94) 2012; 106 Eggleton (10.1016/j.freeradbiomed.2020.01.179_bib104) 2013; 57 Edgar (10.1016/j.freeradbiomed.2020.01.179_bib7) 1955; 48 Gehring (10.1016/j.freeradbiomed.2020.01.179_bib135) 2013; 121 Zhang (10.1016/j.freeradbiomed.2020.01.179_bib131) 2017; 17 Matthews (10.1016/j.freeradbiomed.2020.01.179_bib68) 2015; 54 Bafadhel (10.1016/j.freeradbiomed.2020.01.179_bib121) 2011; 184 Kumar (10.1016/j.freeradbiomed.2020.01.179_bib37) 2016; 12 Mutlu (10.1016/j.freeradbiomed.2020.01.179_bib42) 2007; 117 Salvi (10.1016/j.freeradbiomed.2020.01.179_bib87) 2000; 161 Pfeffer (10.1016/j.freeradbiomed.2020.01.179_bib122) 2019; 199 Bosson (10.1016/j.freeradbiomed.2020.01.179_bib6) 2019; 200 Castaneda (10.1016/j.freeradbiomed.2020.01.179_bib81) 2018; 6 Clark (10.1016/j.freeradbiomed.2020.01.179_bib129) 2010; 118 van Eeden (10.1016/j.freeradbiomed.2020.01.179_bib145) 2001; 164 Heal (10.1016/j.freeradbiomed.2020.01.179_bib3) 2012; 41 Becker (10.1016/j.freeradbiomed.2020.01.179_bib11) 2005; 203 van der Vliet (10.1016/j.freeradbiomed.2020.01.179_bib30) 1999; 276 Zhao (10.1016/j.freeradbiomed.2020.01.179_bib108) 2016; 39 Bloemsma (10.1016/j.freeradbiomed.2020.01.179_bib117) 2016; 151 Kim (10.1016/j.freeradbiomed.2020.01.179_bib133) 2018; 4 Choy (10.1016/j.freeradbiomed.2020.01.179_bib78) 2015; 7 Lichtveld (10.1016/j.freeradbiomed.2020.01.179_bib28) 2012; 46 Fraternale (10.1016/j.freeradbiomed.2020.01.179_bib62) 2010; 28 Mann (10.1016/j.freeradbiomed.2020.01.179_bib69) 2017; 57 Zelante (10.1016/j.freeradbiomed.2020.01.179_bib22) 2013; 39 Durham (10.1016/j.freeradbiomed.2020.01.179_bib98) 2000; 106 Contoli (10.1016/j.freeradbiomed.2020.01.179_bib115) 2015; 70 O'Beirne (10.1016/j.freeradbiomed.2020.01.179_bib151) 2018; 198 Robinson (10.1016/j.freeradbiomed.2020.01.179_bib147) 2018; 141 Porter (10.1016/j.freeradbiomed.2020.01.179_bib63) 2007; 37 Sasaki (10.1016/j.freeradbiomed.2020.01.179_bib73) 2009; 148 Mortaz (10.1016/j.freeradbiomed.2020.01.179_bib99) 2012; 11 Baiz (10.1016/j.freeradbiomed.2020.01.179_bib132) 2011; 11 Busse (10.1016/j.freeradbiomed.2020.01.179_bib111) 2010; 376 Murray (10.1016/j.freeradbiomed.2020.01.179_bib58) 2014; 41 Samet (10.1016/j.freeradbiomed.2020.01.179_bib32) 2001; 164 Hirota (10.1016/j.freeradbiomed.2020.01.179_bib17) 2012; 129 Zheng (10.1016/j.freeradbiomed.2020.01.179_bib120) 2015; 10 Kowalska (10.1016/j.freeradbiomed.2020.01.179_bib21) 2017; 24 Steenhof (10.1016/j.freeradbiomed.2020.01.179_bib34) 2013; 70 De Grove (10.1016/j.freeradbiomed.2020.01.179_bib44) 2018; 48 Zhao (10.1016/j.freeradbiomed.2020.01.179_bib80) 2013; 70 Ayyagari (10.1016/j.freeradbiomed.2020.01.179_bib112) 2007; 19 Mutlu (10.1016/j.freeradbiomed.2020.01.179_bib142) 2011; 8 Kelly (10.1016/j.freeradbiomed.2020.01.179_bib33) 1997; 325 Pfeffer (10.1016/j.freeradbiomed.2020.01.179_bib154) 2018; 13 Becher (10.1016/j.freeradbiomed.2020.01.179_bib39) 2016; 45 Saunders (10.1016/j.freeradbiomed.2020.01.179_bib70) 2010; 118 Zhou (10.1016/j.freeradbiomed.2020.01.179_bib96) 2013; 121 Oberdorster (10.1016/j.freeradbiomed.2020.01.179_bib2) 2005; 113 McCreanor (10.1016/j.freeradbiomed.2020.01.179_bib89) 2007; 357 Kumagai (10.1016/j.freeradbiomed.2020.01.179_bib106) 2017; 30 Wooding (10.1016/j.freeradbiomed.2020.01.179_bib5) 2019; 200 Yarova (10.1016/j.freeradbiomed.2020.01.179_bib16) 2015; 7 Bai (10.1016/j.freeradbiomed.2020.01.179_bib53) 2015; 74 Bose (10.1016/j.freeradbiomed.2020.01.179_bib128) 2018; 167 Bharadwaj (10.1016/j.freeradbiomed.2020.01.179_bib126) 2016; 194 Ishii (10.1016/j.freeradbiomed.2020.01.179_bib27) 2005; 6 Chambers (10.1016/j.freeradbiomed.2020.01.179_bib79) 2015; 136 Pathmanathan (10.1016/j.freeradbiomed.2020.01.179_bib46) 2002; 60 Scandalios (10.1016/j.freeradbiomed.2020.01.179_bib12) 2005; 38 Salvi (10.1016/j.freeradbiomed.2020.01.179_bib86) 1999; 159 Janssen (10.1016/j.freeradbiomed.2020.01.179_bib92) 2004; 15 Ponce-Gallegos (10.1016/j.freeradbiomed.2020.01.179_bib102) 2017; 12 Ribeiro (10.1016/j.freeradbiomed.2020.01.179_bib107) 2017; 599–600 Devalia (10.1016/j.freeradbiomed.2020.01.179_bib45) 1993; 9 Gonzalez-Maciel (10.1016/j.freeradbiomed.2020.01.179_bib148) 2017; 59 Terashima (10.1016/j.freeradbiomed.2020.01.179_bib52) 1997; 155 Martinez (10.1016/j.freeradbiomed.2020.01.179_bib123) 2019; 39 Rahman (10.1016/j.freeradbiomed.2020.01.179_bib35) 1999; 277 Brown (10.1016/j.freeradbiomed.2020.01.179_bib15) 2007; 292 Lin (10.1016/j.freeradbiomed.2020.01.179_bib97) 2017; 8 Jackson (10.1016/j.freeradbiomed.2020.01.179_bib116) 2014; 190 Elahi (10.1016/j.freeradbiomed.2020.01.179_bib59) 2008; 376 Goldstein (10.1016/j.freeradbiomed.2020.01.179_bib50) 1977; 115 Hsu (10.1016/j.freeradbiomed.2020.01.179_bib127) 2015; 192 Blomberg (10.1016/j.freeradbiomed.2020.01.179_bib90) 1999; 159 Nadeau (10.1016/j.freeradbiomed.2020.01.179_bib101) 2010; 126 |
| References_xml | – volume: 118 start-page: 640 year: 2010 end-page: 646 ident: bib70 article-title: Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent publication-title: Environ. Health Perspect. – volume: 15 start-page: S55 year: 2004 end-page: S66 ident: bib92 article-title: Exposure to air pollution from heavy traffic is associated with increased eosinophilic activation in Dutch schoolchildren publication-title: Epidemiology – volume: 200 start-page: 565 year: 2019 end-page: 574 ident: bib5 article-title: Particle depletion does not remediate acute effects of traffic-related air pollution and allergen. A randomized, double-blind crossover study publication-title: Am. J. Respir. Crit. Care Med. – volume: 109 start-page: 250 year: 2003 end-page: 265 ident: bib25 article-title: Particulate air pollutants and asthma - a paradigm for the role of oxidative stress in PM-induced adverse health effects publication-title: Clin. Immunol. – volume: 70 start-page: 426 year: 2013 end-page: 431 ident: bib80 article-title: The biological effects of individual-level PM(2.5) exposure on systemic immunity and inflammatory response in traffic policemen publication-title: Occup. Environ. Med. – volume: 24 start-page: 1993 year: 2010 end-page: 2002 ident: bib20 article-title: Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species publication-title: Toxicol. Vitro : Int. J. Publ. Assoc. BIBRA – volume: 94 start-page: 1417 year: 1994 end-page: 1425 ident: bib82 article-title: Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms publication-title: J. Clin. Invest. – volume: 277 start-page: L1067 year: 1999 end-page: L1088 ident: bib35 article-title: Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease publication-title: Am. J. Physiol. – volume: 140 start-page: 1 year: 2017 end-page: 12 ident: bib125 article-title: Environmental determinants of allergy and asthma in early life publication-title: J. Allergy Clin. Immunol. – volume: 20 start-page: 399 year: 2008 end-page: 414 ident: bib24 article-title: Effects of particulate matter on cytokine production in vitro: a comparative analysis of published studies publication-title: Inhal. Toxicol. – volume: 370 start-page: 20140049 year: 2015 ident: bib38 article-title: Nanoparticles modulate surfactant protein A and D mediated protection against influenza A infection in vitro publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. – volume: 121 start-page: 1357 year: 2013 end-page: 1364 ident: bib135 article-title: Air pollution exposure and lung function in children: the ESCAPE project publication-title: Environ. Health Perspect. – volume: 17 start-page: 1138 year: 2011 end-page: 1145 ident: bib140 article-title: Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis publication-title: Inflamm. Bowel Dis. – volume: 15 start-page: 1 year: 2012 end-page: 21 ident: bib4 article-title: Composition of air pollution particles and oxidative stress in cells, tissues, and living systems publication-title: J. Toxicol. Environ. Health B Crit. Rev. – volume: 10 start-page: 3866 year: 2019 ident: bib124 article-title: Ambient black carbon particles reach the fetal side of human placenta publication-title: Nat. Commun. – volume: 11 start-page: 87 year: 2011 ident: bib132 article-title: Maternal exposure to air pollution before and during pregnancy related to changes in newborn's cord blood lymphocyte subpopulations. The EDEN study cohort publication-title: BMC Pregnancy Childbirth – volume: 32 start-page: 403 year: 2014 end-page: 432 ident: bib19 article-title: The aryl hydrocarbon receptor: multitasking in the immune system publication-title: Annu. Rev. Immunol. – volume: 101 start-page: 1140 year: 2007 end-page: 1146 ident: bib88 article-title: Ozone enhances the airway inflammation initiated by diesel exhaust publication-title: Respir. Med. – volume: 126 start-page: 845 year: 2010 end-page: 852 ident: bib101 article-title: Ambient air pollution impairs regulatory T-cell function in asthma publication-title: J. Allergy Clin. Immunol. – volume: 54 start-page: 250 year: 2015 end-page: 262 ident: bib68 article-title: Urban particulate matter-activated human dendritic cells induce the expansion of potent inflammatory Th1, Th2 and Th17 effector cells publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 94 start-page: 1167 year: 2013 end-page: 1184 ident: bib9 article-title: Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation publication-title: J. Leukoc. Biol. – volume: 6 year: 2018 ident: bib81 article-title: Ambient particulate matter enhances the pulmonary allergic immune response to house dust mite in a BALB/c mouse model by augmenting Th2- and Th17-immune responses publication-title: Phys. Rep. – volume: 106 start-page: S221 year: 2000 end-page: S226 ident: bib98 article-title: T lymphocytes in asthma: bronchial versus peripheral responses publication-title: J. Allergy Clin. Immunol. – volume: 113 start-page: 823 year: 2005 end-page: 839 ident: bib2 article-title: Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles publication-title: Environ. Health Perspect. – volume: 117 start-page: 2952 year: 2007 end-page: 2961 ident: bib42 article-title: Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway publication-title: J. Clin. Invest. – volume: 19 start-page: 181 year: 2007 end-page: 194 ident: bib112 article-title: Effects of nitrogen dioxide on the expression of intercellular adhesion molecule-1, neutrophil adhesion, and cytotoxicity: studies in human bronchial epithelial cells publication-title: Inhal. Toxicol. – volume: 176 start-page: 7431 year: 2006 end-page: 7437 ident: bib66 article-title: Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation publication-title: J. Immunol. – volume: 110 start-page: 1670 year: 2004 end-page: 1677 ident: bib95 article-title: Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters publication-title: Circulation – volume: 194 start-page: 1475 year: 2016 end-page: 1482 ident: bib126 article-title: Early-life exposure to the Great smog of 1952 and the development of asthma publication-title: Am. J. Respir. Crit. Care Med. – volume: 292 start-page: L1444 year: 2007 end-page: L1451 ident: bib15 article-title: The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists publication-title: Am. J. Physiol. Lung Cell Mol. Physiol. – volume: 57 start-page: 355 year: 2017 end-page: 366 ident: bib69 article-title: Vitamin D counteracts an IL-23-dependent IL-17a(+)IFN-gamma(+) response driven by urban particulate matter publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 136 start-page: 628 year: 2015 end-page: 637 ident: bib79 article-title: Distinct endotypes of steroid-resistant asthma characterized by IL-17A and IFN-gamma immunophenotypes: potential benefits of calcitriol publication-title: J. Allergy Clin. Immunol. – volume: 161 start-page: 550 year: 2000 end-page: 557 ident: bib87 article-title: Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways publication-title: Am. J. Respir. Crit. Care Med. – volume: 27 start-page: 34 year: 2002 end-page: 41 ident: bib26 article-title: Interaction of alveolar macrophages and airway epithelial cells following exposure to particulate matter produces mediators that stimulate the bone marrow publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 7 start-page: 301RA129 year: 2015 ident: bib78 article-title: TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma publication-title: Sci. Transl. Med. – volume: 166 start-page: 76 year: 2002 end-page: 84 ident: bib136 article-title: Association between air pollution and lung function growth in southern California children: results from a second cohort publication-title: Am. J. Respir. Crit. Care Med. – volume: 121 start-page: 3195 year: 2013 end-page: 3204 ident: bib96 article-title: Aryl hydrocarbon receptor controls murine mast cell homeostasis publication-title: Blood – volume: 6 start-page: 87 year: 2005 ident: bib27 article-title: Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment publication-title: Respir. Res. – volume: 119 start-page: 1225 year: 2007 end-page: 1233 ident: bib60 article-title: Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence publication-title: J. Allergy Clin. Immunol. – volume: 132 start-page: 1194 year: 2013 end-page: 1204 e2 ident: bib71 article-title: Diesel exhaust particle induction of IL-17A contributes to severe asthma publication-title: J. Allergy Clin. Immunol. – volume: 6 start-page: 272 year: 2009 end-page: 277 ident: bib138 article-title: The origins of asthma and chronic obstructive pulmonary disease in early life publication-title: Proc. Am. Thorac. Soc. – volume: 164 start-page: 826 year: 2001 end-page: 830 ident: bib145 article-title: Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)) publication-title: Am. J. Respir. Crit. Care Med. – volume: 86 start-page: 303 year: 2009 end-page: 312 ident: bib10 article-title: Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter publication-title: J. Leukoc. Biol. – volume: 24 start-page: 24223 year: 2017 end-page: 24234 ident: bib21 article-title: Genotoxic potential of diesel exhaust particles from the combustion of first- and second-generation biodiesel fuels-the FuelHealth project publication-title: Environ. Sci. Pollut. Res. Int. – volume: 37 start-page: 706 year: 2007 end-page: 719 ident: bib63 article-title: Diesel-enriched particulate matter functionally activates human dendritic cells publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 376 start-page: 445 year: 2008 end-page: 447 ident: bib59 article-title: Functional adaptation to oxidative stress by memory T cells: an analysis of the role in the cardiovascular disease process publication-title: Biochem. Biophys. Res. Commun. – volume: 17 start-page: 495 year: 2017 end-page: 507 ident: bib131 article-title: Unique aspects of the perinatal immune system publication-title: Nat. Rev. Immunol. – volume: 106 start-page: 9 year: 2012 end-page: 14 ident: bib94 article-title: The role of mast cells in allergic inflammation publication-title: Respir. Med. – volume: 30 start-page: 203 year: 2017 end-page: 219 ident: bib106 article-title: Environmental electrophiles: protein adducts, modulation of redox signaling, and interaction with persulfides/polysulfides publication-title: Chem. Res. Toxicol. – volume: 50 start-page: 281 year: 2014 end-page: 291 ident: bib64 article-title: Urban particulate matter suppresses priming of Th1 cells by GM-CSF-activated human dendritic cells publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 184 start-page: 662 year: 2011 end-page: 671 ident: bib121 article-title: Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers publication-title: Am. J. Respir. Crit. Care Med. – volume: 4 start-page: e28 year: 2019 end-page: e40 ident: bib134 article-title: Impact of London's low emission zone on air quality and children's respiratory health: a sequential annual cross-sectional study publication-title: Lancet Public Health – volume: 6 start-page: 1308 year: 1993 end-page: 1316 ident: bib49 article-title: Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide publication-title: Eur. Respir. J. – volume: 599–600 start-page: 291 year: 2017 end-page: 297 ident: bib107 article-title: Effect of O3 and NO2 atmospheric pollutants on Platanus x acerifolia pollen: immunochemical and spectroscopic analysis publication-title: Sci. Total Environ. – volume: 105 start-page: 1534 year: 2002 end-page: 1536 ident: bib146 article-title: Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults publication-title: Circulation – volume: 198 start-page: 1362 year: 2018 end-page: 1363 ident: bib150 article-title: The impact of real-world particulate matter air pollution on the airways of susceptible individuals publication-title: Am. J. Respir. Crit. Care Med. – volume: 35 start-page: 1039 year: 2010 end-page: 1047 ident: bib113 article-title: Defective macrophage phagocytosis of bacteria in COPD publication-title: Eur. Respir. J. – volume: 118 start-page: 120 year: 2010 end-page: 124 ident: bib41 article-title: Baseline repeated measures from controlled human exposure studies: associations between ambient air pollution exposure and the systemic inflammatory biomarkers IL-6 and fibrinogen publication-title: Environ. Health Perspect. – volume: 8 start-page: 166 year: 2012 end-page: 175 ident: bib1 article-title: Clearing the air: a review of the effects of particulate matter air pollution on human health publication-title: J. Med. Toxicol. – volume: 13 year: 2018 ident: bib154 article-title: Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter publication-title: PloS One – volume: 8 year: 2013 ident: bib143 article-title: Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome publication-title: PloS One – volume: 148 start-page: 239 year: 2009 end-page: 250 ident: bib73 article-title: Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production publication-title: Int. Arch. Allergy Immunol. – volume: 198 start-page: 1413 year: 2018 end-page: 1422 ident: bib151 article-title: Ambient pollution-related reprogramming of the human small airway epithelial transcriptome publication-title: Am. J. Respir. Crit. Care Med. – volume: 453 start-page: 65 year: 2008 end-page: 71 ident: bib23 article-title: Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor publication-title: Nature – volume: 28 start-page: 7676 year: 2010 end-page: 7682 ident: bib62 article-title: The increase in intra-macrophage thiols induced by new pro-GSH molecules directs the Th1 skewing in ovalbumin immunized mice publication-title: Vaccine – volume: 39 start-page: 147 year: 2016 end-page: 164 ident: bib108 article-title: Common ragweed (Ambrosia artemisiifolia L.): allergenicity and molecular characterization of pollen after plant exposure to elevated NO2 publication-title: Plant Cell Environ. – volume: 176 start-page: 108567 year: 2019 ident: bib149 article-title: Combustion- and friction-derived magnetic air pollution nanoparticles in human hearts publication-title: Environ. Res. – volume: 59 start-page: 189 year: 2017 end-page: 208 ident: bib148 article-title: Combustion-derived nanoparticles in key brain target cells and organelles in young urbanites: culprit hidden in plain sight in alzheimer's disease development publication-title: J. Alzheim. Dis. – volume: 141 start-page: 1074 year: 2018 end-page: 1084 ident: bib147 article-title: Mechanistic link between diesel exhaust particles and respiratory reflexes publication-title: J. Allergy Clin. Immunol. – volume: 115 start-page: 403 year: 1977 end-page: 412 ident: bib50 article-title: Fate and distribution of inhaled nitrogen dioxide in rhesus monkeys publication-title: Am. Rev. Respir. Dis. – volume: 155 start-page: 1441 year: 1997 end-page: 1447 ident: bib52 article-title: Phagocytosis of small carbon particles (PM10) by alveolar macrophages stimulates the release of polymorphonuclear leukocytes from bone marrow publication-title: Am. J. Respir. Crit. Care Med. – volume: 41 start-page: 6606 year: 2012 end-page: 6630 ident: bib3 article-title: Particles, air quality, policy and health publication-title: Chem. Soc. Rev. – volume: 9 start-page: 72 year: 2012 end-page: 76 ident: bib74 article-title: Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro publication-title: J. Immunot. – volume: 376 start-page: 826 year: 2010 end-page: 834 ident: bib111 article-title: Role of viral respiratory infections in asthma and asthma exacerbations publication-title: Lancet – volume: 57 start-page: 79 year: 2013 end-page: 91 ident: bib104 article-title: Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens publication-title: Free Radic. Biol. Med. – volume: 241 start-page: 511 year: 2018 end-page: 520 ident: bib139 article-title: Pre- and postnatal exposure of mice to concentrated urban PM2.5 decreases the number of alveoli and leads to altered lung function at an early stage of life publication-title: Environ. Pollut. – volume: 8 start-page: 19 year: 2011 ident: bib142 article-title: Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice publication-title: Part. Fibre Toxicol. – volume: 28 start-page: S54 year: 2017 end-page: S59 ident: bib110 article-title: Air pollution as a potential determinant of rheumatoid arthritis: a population-based cohort study in taiwan publication-title: Epidemiology – volume: 7 start-page: 284ra60 year: 2015 ident: bib16 article-title: Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma publication-title: Sci. Transl. Med. – volume: 129 start-page: 1116 year: 2012 end-page: 11125 e6 ident: bib17 article-title: The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter publication-title: J. Allergy Clin. Immunol. – volume: 159 start-page: 536 year: 1999 end-page: 543 ident: bib90 article-title: Persistent airway inflammation but accommodated antioxidant and lung function responses after repeated daily exposure to nitrogen dioxide publication-title: Am. J. Respir. Crit. Care Med. – volume: 200 start-page: 523 year: 2019 end-page: 524 ident: bib6 article-title: Traffic-related air pollution, health, and allergy: the role of nitrogen dioxide publication-title: Am. J. Respir. Crit. Care Med. – volume: 372 start-page: 905 year: 2015 end-page: 913 ident: bib137 article-title: Association of improved air quality with lung development in children publication-title: N. Engl. J. Med. – volume: 54 start-page: 5185 year: 2015 end-page: 5197 ident: bib105 article-title: Environmental pollutant ozone causes damage to lung surfactant protein B (SP-B) publication-title: Biochemistry – volume: 164 start-page: 819 year: 2001 end-page: 825 ident: bib32 article-title: Effect of antioxidant supplementation on ozone-induced lung injury in human subjects publication-title: Am. J. Respir. Crit. Care Med. – volume: 9 start-page: 271 year: 1993 end-page: 278 ident: bib45 article-title: Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 190 start-page: 1373 year: 2014 end-page: 1382 ident: bib116 article-title: IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo publication-title: Am. J. Respir. Crit. Care Med. – volume: 56 start-page: 839 year: 1989 end-page: 847 ident: bib47 article-title: The major human rhinovirus receptor is ICAM-1 publication-title: Cell – volume: 203 start-page: 45 year: 2005 end-page: 52 ident: bib11 article-title: TLR-2 is involved in airway epithelial cell response to air pollution particles publication-title: Toxicol. Appl. Pharmacol. – volume: 159 start-page: 702 year: 1999 end-page: 709 ident: bib86 article-title: Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers publication-title: Am. J. Respir. Crit. Care Med. – volume: 120 start-page: 722 year: 2015 end-page: 728 ident: bib75 article-title: Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway publication-title: Chemosphere – volume: 41 start-page: 14 year: 2014 end-page: 20 ident: bib58 article-title: Macrophage activation and polarization: nomenclature and experimental guidelines publication-title: Immunity – volume: 357 start-page: 2348 year: 2007 end-page: 2358 ident: bib89 article-title: Respiratory effects of exposure to diesel traffic in persons with asthma publication-title: N. Engl. J. Med. – volume: 28 start-page: 147 year: 2008 end-page: 156 ident: bib67 article-title: Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin publication-title: J. Clin. Immunol. – volume: 38 start-page: 995 year: 2005 end-page: 1014 ident: bib12 article-title: Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses publication-title: Braz. J. Med. Biol. Res. – volume: 453 start-page: 106 year: 2008 end-page: 109 ident: bib144 article-title: The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins publication-title: Nature – volume: 325 start-page: 95 year: 1997 end-page: 99 ident: bib33 article-title: Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid publication-title: Biochem. J. – volume: 153 start-page: 1031 year: 2001 end-page: 1044 ident: bib18 article-title: Health effects of dioxin exposure: a 20-year mortality study publication-title: Am. J. Epidemiol. – volume: 12 start-page: 1857 year: 2017 end-page: 1865 ident: bib102 article-title: Th17 profile in COPD exacerbations publication-title: Int. J. Chronic Obstr. Pulm. Dis. – volume: 39 start-page: 372 year: 2013 end-page: 385 ident: bib22 article-title: Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22 publication-title: Immunity – volume: 100 start-page: 1 year: 2017 end-page: 31 ident: bib109 article-title: Exposure to traffic-related air pollution and risk of development of childhood asthma: a systematic review and meta-analysis publication-title: Environ. Int. – volume: 60 start-page: 504 year: 2012 end-page: 526 ident: bib85 article-title: Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter publication-title: Atmos. Environ. – volume: 161 start-page: 304 year: 2018 end-page: 313 ident: bib72 article-title: Unique pulmonary immunotoxicological effects of urban PM are not recapitulated solely by carbon black, diesel exhaust or coal fly ash publication-title: Environ. Res. – volume: 12 year: 2017 ident: bib119 article-title: Effect of outdoor air pollution on asthma exacerbations in children and adults: systematic review and multilevel meta-analysis publication-title: PloS One – volume: 60 start-page: 892 year: 2002 end-page: 896 ident: bib46 article-title: Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways publication-title: Occup. Environ. Med. – volume: 199 start-page: 581 year: 2019 end-page: 591 ident: bib122 article-title: Increased chronic obstructive pulmonary disease exacerbations of likely viral etiology follow elevated ambient nitrogen oxides publication-title: Am. J. Respir. Crit. Care Med. – volume: 73 start-page: 418 year: 1995 end-page: 422 ident: bib91 article-title: Bronchial responsiveness, eosinophilia, and short term exposure to air pollution publication-title: Arch. Dis. Child. – volume: 9 start-page: 334 year: 1996 end-page: 339 ident: bib36 article-title: Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress publication-title: Eur. Respir. J. – volume: 9 start-page: 2298 year: 1996 end-page: 2305 ident: bib51 article-title: Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium publication-title: Eur. Respir. J. – volume: 70 start-page: 910 year: 2015 end-page: 920 ident: bib115 article-title: Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells publication-title: Allergy – volume: 48 start-page: 1498 year: 1955 end-page: 1504 ident: bib7 article-title: Reactions of nitrogen dioxide and organic compounds in air publication-title: Ind. Eng. Chem. – volume: 354 start-page: 482 year: 1999 end-page: 483 ident: bib8 article-title: Altered lung antioxidant status in patients with mild asthma publication-title: Lancet – volume: 11 start-page: 3079 year: 2016 end-page: 3091 ident: bib118 article-title: Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis publication-title: Int. J. Chronic Obstr. Pulm. Dis. – volume: 192 start-page: 1052 year: 2015 end-page: 1059 ident: bib127 article-title: Prenatal particulate air pollution and asthma onset in urban children. Identifying sensitive windows and sex differences publication-title: Am. J. Respir. Crit. Care Med. – volume: 299 start-page: 1033 year: 2003 end-page: 1036 ident: bib100 article-title: Toll pathway–dependent blockade of CD4+CD25+ T cell–mediated suppression by dendritic cells publication-title: Science – volume: 73 start-page: 2192 year: 2018 end-page: 2204 ident: bib43 article-title: Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma publication-title: Allergy – volume: 153 start-page: 1229 year: 2017 end-page: 1239 ident: bib152 article-title: Vitamin D in asthma: mechanisms of action and considerations for clinical trials publication-title: Chest – volume: 88 start-page: 565 year: 1996 end-page: 568 ident: bib48 article-title: Induction of intercellular adhesion molecule-1 in human nasal epithelial cells during respiratory syncytial virus infection publication-title: Immunology – volume: 355 start-page: 21 year: 2006 end-page: 30 ident: bib56 article-title: Carbon in airway macrophages and lung function in children publication-title: N. Engl. J. Med. – volume: 151 start-page: 458 year: 2016 end-page: 468 ident: bib117 article-title: Panel studies of air pollution in patients with COPD: systematic review and meta-analysis publication-title: Environ. Res. – volume: 2 start-page: 715 year: 2014 end-page: 724 ident: bib103 article-title: Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases publication-title: Redox Biol. – volume: 6 year: 2011 ident: bib55 article-title: Traffic air pollution and oxidized LDL publication-title: PloS One – volume: 95 start-page: 3071 year: 1998 end-page: 3076 ident: bib61 article-title: Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns publication-title: Proc. Natl. Acad. Sci. U. S. A – volume: 153 start-page: 502 year: 2017 end-page: 512 ident: bib65 article-title: Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD8 T lymphocytes publication-title: Immunology – volume: 11 start-page: 6 year: 2012 end-page: 17 ident: bib99 article-title: Immunological features of chronic obstructive pulmonary disease (COPD) induced by indoor pollution and cigarette smoke publication-title: Tanaffos – volume: 45 start-page: 963 year: 2016 end-page: 973 ident: bib39 article-title: GM-CSF: From growth factor to central mediator of tissue inflammation publication-title: Immunity – volume: 10 start-page: 343 year: 2015 end-page: 345 ident: bib29 article-title: What are the biological and therapeutic implications of biomolecule corona formation on the surface of inhaled nanomedicines? publication-title: Nanomedicine (Lond.) – volume: 62 start-page: 355 year: 2005 end-page: 362 ident: bib84 article-title: The London Underground: dust and hazards to health publication-title: Occup. Environ. Med. – volume: 46 start-page: 9062 year: 2012 end-page: 9070 ident: bib28 article-title: In vitro exposures in diesel exhaust atmospheres: resuspension of PM from filters versus direct deposition of PM from air publication-title: Environ. Sci. Technol. – volume: 118 start-page: 284 year: 2010 end-page: 290 ident: bib129 article-title: Effect of early life exposure to air pollution on development of childhood asthma publication-title: Environ. Health Perspect. – volume: 105 start-page: 2412 year: 2010 end-page: 2419 ident: bib141 article-title: The inflammatory bowel diseases and ambient air pollution: a novel association publication-title: Am. J. Gastroenterol. – volume: 47 start-page: 89 year: 2007 end-page: 116 ident: bib13 article-title: Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway publication-title: Annu. Rev. Pharmacol. Toxicol. – volume: 5 start-page: 953 year: 2005 end-page: 964 ident: bib57 article-title: Monocyte and macrophage heterogeneity publication-title: Nat. Rev. Immunol. – volume: 21 start-page: 933 year: 2009 end-page: 942 ident: bib31 article-title: Antioxidant responses to acute ozone challenge in the healthy human airway publication-title: Inhal. Toxicol. – volume: 275 start-page: C1 year: 1998 end-page: C24 ident: bib14 article-title: Interaction of reactive oxygen species with ion transport mechanisms publication-title: Am. J. Physiol. – volume: 143 start-page: 83 year: 2015 end-page: 92 ident: bib130 article-title: Early life exposure to ambient air pollution and childhood asthma in China publication-title: Environ. Res. – volume: 167 start-page: 591 year: 2018 end-page: 597 ident: bib128 article-title: Prenatal nitrate air pollution exposure and reduced child lung function: timing and fetal sex effects publication-title: Environ. Res. – volume: 8 start-page: 1781 year: 2017 ident: bib97 article-title: Granulocytes: new members of the antigen-presenting cell family publication-title: Front. Immunol. – volume: 48 start-page: 1665 year: 2018 end-page: 1675 ident: bib44 article-title: IL-33 signalling contributes to pollutant-induced allergic airway inflammation publication-title: Clin. Exp. Allergy – volume: 74 start-page: 32 year: 2015 end-page: 41 ident: bib53 article-title: Carbon loading in airway macrophages as a biomarker for individual exposure to particulate matter air pollution - a critical review publication-title: Environ. Int. – volume: 39 start-page: 141 year: 2019 end-page: 150 ident: bib123 article-title: Childhood asthma inception and progression: role of microbial exposures, susceptibility to viruses and early allergic sensitization publication-title: Immunol. Allergy Clin. – volume: 49 start-page: 915 year: 2018 end-page: 928 e5 ident: bib77 article-title: Aryl hydrocarbon receptor signaling cell intrinsically inhibits intestinal group 2 innate lymphoid cell function publication-title: Immunity – volume: 4 start-page: 75 year: 2018 end-page: 94 ident: bib133 article-title: Air pollutants and early origins of respiratory diseases publication-title: Chronic Dis. Transl. Med. – volume: 57 start-page: 59 year: 2017 end-page: 65 ident: bib93 article-title: Airborne particulate matter induces nonallergic eosinophilic sinonasal inflammation in mice publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 5 start-page: 605 year: 2012 end-page: 609 ident: bib114 article-title: The alveolar macrophages in asthma: a double-edged sword publication-title: Mucosal Immunol. – volume: 276 start-page: L289 year: 1999 end-page: L296 ident: bib30 article-title: Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids publication-title: Am. J. Physiol. – volume: 131 start-page: 465 year: 2009 end-page: 469 ident: bib83 article-title: Phagocytic leukocytes and reactive oxygen species publication-title: Histochem. Cell Biol. – volume: 190 start-page: 1190 year: 2014 end-page: 1192 ident: bib153 article-title: Proximity to a major road, vitamin D insufficiency, and severe asthma exacerbations in Puerto Rican children publication-title: Am. J. Respir. Crit. Care Med. – volume: 70 start-page: 341 year: 2013 end-page: 348 ident: bib34 article-title: Acute nasal pro-inflammatory response to air pollution depends on characteristics other than particle mass concentration or oxidative potential: the RAPTES project publication-title: Occup. Environ. Med. – volume: 10 year: 2015 ident: bib120 article-title: Association between air pollutants and asthma emergency room visits and hospital admissions in time series studies: a systematic review and meta-analysis publication-title: PloS One – volume: 44 start-page: 197 year: 2011 end-page: 204 ident: bib40 article-title: Particulate matter induces translocation of IL-6 from the lung to the systemic circulation publication-title: Am. J. Respir. Cell Mol. Biol. – volume: 10 start-page: 369 year: 1988 end-page: 384 ident: bib54 article-title: Possible mechanisms to explain dust overloading of the lungs publication-title: Fund. Appl. Toxicol. – volume: 12 start-page: 1033 year: 2016 end-page: 1043 ident: bib37 article-title: Enrichment of immunoregulatory proteins in the biomolecular corona of nanoparticles within human respiratory tract lining fluid publication-title: Nanomedicine – volume: 49 start-page: 353 year: 2018 end-page: 362 ident: bib76 article-title: The environmental sensor AHR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity publication-title: Immunity – volume: 9 start-page: 2298 issue: 11 year: 1996 ident: 10.1016/j.freeradbiomed.2020.01.179_bib51 article-title: Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium publication-title: Eur. Respir. J. doi: 10.1183/09031936.96.09112298 – volume: 167 start-page: 591 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib128 article-title: Prenatal nitrate air pollution exposure and reduced child lung function: timing and fetal sex effects publication-title: Environ. Res. doi: 10.1016/j.envres.2018.08.019 – volume: 105 start-page: 1534 issue: 13 year: 2002 ident: 10.1016/j.freeradbiomed.2020.01.179_bib146 article-title: Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults publication-title: Circulation doi: 10.1161/01.CIR.0000013838.94747.64 – volume: 198 start-page: 1362 issue: 11 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib150 article-title: The impact of real-world particulate matter air pollution on the airways of susceptible individuals publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201807-1206ED – volume: 100 start-page: 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib109 article-title: Exposure to traffic-related air pollution and risk of development of childhood asthma: a systematic review and meta-analysis publication-title: Environ. Int. doi: 10.1016/j.envint.2016.11.012 – volume: 118 start-page: 640 issue: 5 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib70 article-title: Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent publication-title: Environ. Health Perspect. doi: 10.1289/ehp.0901461 – volume: 164 start-page: 826 issue: 5 year: 2001 ident: 10.1016/j.freeradbiomed.2020.01.179_bib145 article-title: Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)) publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.164.5.2010160 – volume: 129 start-page: 1116 issue: 4 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib17 article-title: The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2011.11.033 – volume: 88 start-page: 565 issue: 4 year: 1996 ident: 10.1016/j.freeradbiomed.2020.01.179_bib48 article-title: Induction of intercellular adhesion molecule-1 in human nasal epithelial cells during respiratory syncytial virus infection publication-title: Immunology doi: 10.1046/j.1365-2567.1996.d01-687.x – volume: 299 start-page: 1033 year: 2003 ident: 10.1016/j.freeradbiomed.2020.01.179_bib100 article-title: Toll pathway–dependent blockade of CD4+CD25+ T cell–mediated suppression by dendritic cells publication-title: Science doi: 10.1126/science.1078231 – volume: 4 start-page: e28 issue: 1 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib134 article-title: Impact of London's low emission zone on air quality and children's respiratory health: a sequential annual cross-sectional study publication-title: Lancet Public Health doi: 10.1016/S2468-2667(18)30202-0 – volume: 132 start-page: 1194 issue: 5 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib71 article-title: Diesel exhaust particle induction of IL-17A contributes to severe asthma publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2013.06.048 – volume: 41 start-page: 6606 issue: 19 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib3 article-title: Particles, air quality, policy and health publication-title: Chem. Soc. Rev. doi: 10.1039/c2cs35076a – volume: 161 start-page: 304 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib72 article-title: Unique pulmonary immunotoxicological effects of urban PM are not recapitulated solely by carbon black, diesel exhaust or coal fly ash publication-title: Environ. Res. doi: 10.1016/j.envres.2017.10.041 – volume: 161 start-page: 550 issue: 2 Pt 1 year: 2000 ident: 10.1016/j.freeradbiomed.2020.01.179_bib87 article-title: Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.161.2.9905052 – volume: 11 start-page: 3079 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib118 article-title: Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis publication-title: Int. J. Chronic Obstr. Pulm. Dis. doi: 10.2147/COPD.S122282 – volume: 120 start-page: 722 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib75 article-title: Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway publication-title: Chemosphere doi: 10.1016/j.chemosphere.2014.10.039 – volume: 57 start-page: 355 issue: 3 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib69 article-title: Vitamin D counteracts an IL-23-dependent IL-17a(+)IFN-gamma(+) response driven by urban particulate matter publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2016-0409OC – volume: 241 start-page: 511 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib139 article-title: Pre- and postnatal exposure of mice to concentrated urban PM2.5 decreases the number of alveoli and leads to altered lung function at an early stage of life publication-title: Environ. Pollut. doi: 10.1016/j.envpol.2018.05.055 – volume: 44 start-page: 197 issue: 2 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib40 article-title: Particulate matter induces translocation of IL-6 from the lung to the systemic circulation publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2009-0427OC – volume: 74 start-page: 32 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib53 article-title: Carbon loading in airway macrophages as a biomarker for individual exposure to particulate matter air pollution - a critical review publication-title: Environ. Int. doi: 10.1016/j.envint.2014.09.010 – volume: 148 start-page: 239 issue: 3 year: 2009 ident: 10.1016/j.freeradbiomed.2020.01.179_bib73 article-title: Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production publication-title: Int. Arch. Allergy Immunol. doi: 10.1159/000161584 – volume: 357 start-page: 2348 issue: 23 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib89 article-title: Respiratory effects of exposure to diesel traffic in persons with asthma publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa071535 – volume: 49 start-page: 915 issue: 5 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib77 article-title: Aryl hydrocarbon receptor signaling cell intrinsically inhibits intestinal group 2 innate lymphoid cell function publication-title: Immunity doi: 10.1016/j.immuni.2018.09.015 – volume: 28 start-page: 7676 issue: 48 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib62 article-title: The increase in intra-macrophage thiols induced by new pro-GSH molecules directs the Th1 skewing in ovalbumin immunized mice publication-title: Vaccine doi: 10.1016/j.vaccine.2010.09.033 – volume: 8 issue: 4 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib143 article-title: Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome publication-title: PloS One doi: 10.1371/journal.pone.0062220 – volume: 54 start-page: 5185 issue: 33 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib105 article-title: Environmental pollutant ozone causes damage to lung surfactant protein B (SP-B) publication-title: Biochemistry doi: 10.1021/acs.biochem.5b00308 – volume: 355 start-page: 21 issue: 1 year: 2006 ident: 10.1016/j.freeradbiomed.2020.01.179_bib56 article-title: Carbon in airway macrophages and lung function in children publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa052972 – volume: 121 start-page: 3195 issue: 16 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib96 article-title: Aryl hydrocarbon receptor controls murine mast cell homeostasis publication-title: Blood doi: 10.1182/blood-2012-08-453597 – volume: 24 start-page: 24223 issue: 31 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib21 article-title: Genotoxic potential of diesel exhaust particles from the combustion of first- and second-generation biodiesel fuels-the FuelHealth project publication-title: Environ. Sci. Pollut. Res. Int. doi: 10.1007/s11356-017-9995-0 – volume: 176 start-page: 108567 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib149 article-title: Combustion- and friction-derived magnetic air pollution nanoparticles in human hearts publication-title: Environ. Res. doi: 10.1016/j.envres.2019.108567 – volume: 9 start-page: 271 issue: 3 year: 1993 ident: 10.1016/j.freeradbiomed.2020.01.179_bib45 article-title: Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/ajrcmb/9.3.271 – volume: 106 start-page: S221 issue: 5 year: 2000 ident: 10.1016/j.freeradbiomed.2020.01.179_bib98 article-title: T lymphocytes in asthma: bronchial versus peripheral responses publication-title: J. Allergy Clin. Immunol. doi: 10.1067/mai.2000.110154 – volume: 30 start-page: 203 issue: 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib106 article-title: Environmental electrophiles: protein adducts, modulation of redox signaling, and interaction with persulfides/polysulfides publication-title: Chem. Res. Toxicol. doi: 10.1021/acs.chemrestox.6b00326 – volume: 10 issue: 9 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib120 article-title: Association between air pollutants and asthma emergency room visits and hospital admissions in time series studies: a systematic review and meta-analysis publication-title: PloS One doi: 10.1371/journal.pone.0138146 – volume: 6 start-page: 87 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib27 article-title: Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment publication-title: Respir. Res. doi: 10.1186/1465-9921-6-87 – volume: 113 start-page: 823 issue: 7 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib2 article-title: Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles publication-title: Environ. Health Perspect. doi: 10.1289/ehp.7339 – volume: 73 start-page: 2192 issue: 11 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib43 article-title: Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma publication-title: Allergy doi: 10.1111/all.13462 – volume: 47 start-page: 89 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib13 article-title: Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway publication-title: Annu. Rev. Pharmacol. Toxicol. doi: 10.1146/annurev.pharmtox.46.120604.141046 – volume: 94 start-page: 1417 year: 1994 ident: 10.1016/j.freeradbiomed.2020.01.179_bib82 article-title: Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms publication-title: J. Clin. Invest. doi: 10.1172/JCI117478 – volume: 166 start-page: 76 issue: 1 year: 2002 ident: 10.1016/j.freeradbiomed.2020.01.179_bib136 article-title: Association between air pollution and lung function growth in southern California children: results from a second cohort publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.2111021 – volume: 203 start-page: 45 issue: 1 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib11 article-title: TLR-2 is involved in airway epithelial cell response to air pollution particles publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2004.07.007 – volume: 32 start-page: 403 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib19 article-title: The aryl hydrocarbon receptor: multitasking in the immune system publication-title: Annu. Rev. Immunol. doi: 10.1146/annurev-immunol-032713-120245 – volume: 453 start-page: 106 issue: 7191 year: 2008 ident: 10.1016/j.freeradbiomed.2020.01.179_bib144 article-title: The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins publication-title: Nature doi: 10.1038/nature06881 – volume: 48 start-page: 1498 issue: 9 year: 1955 ident: 10.1016/j.freeradbiomed.2020.01.179_bib7 article-title: Reactions of nitrogen dioxide and organic compounds in air publication-title: Ind. Eng. Chem. – volume: 7 start-page: 301RA129 issue: 301 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib78 article-title: TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.aab3142 – volume: 372 start-page: 905 issue: 10 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib137 article-title: Association of improved air quality with lung development in children publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1414123 – volume: 17 start-page: 1138 issue: 5 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib140 article-title: Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis publication-title: Inflamm. Bowel Dis. doi: 10.1002/ibd.21455 – volume: 19 start-page: 181 issue: 2 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib112 article-title: Effects of nitrogen dioxide on the expression of intercellular adhesion molecule-1, neutrophil adhesion, and cytotoxicity: studies in human bronchial epithelial cells publication-title: Inhal. Toxicol. doi: 10.1080/08958370601052121 – volume: 106 start-page: 9 issue: 1 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib94 article-title: The role of mast cells in allergic inflammation publication-title: Respir. Med. doi: 10.1016/j.rmed.2011.09.007 – volume: 119 start-page: 1225 issue: 5 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib60 article-title: Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2007.01.016 – volume: 86 start-page: 303 issue: 2 year: 2009 ident: 10.1016/j.freeradbiomed.2020.01.179_bib10 article-title: Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter publication-title: J. Leukoc. Biol. doi: 10.1189/jlb.1008587 – volume: 155 start-page: 1441 issue: 4 year: 1997 ident: 10.1016/j.freeradbiomed.2020.01.179_bib52 article-title: Phagocytosis of small carbon particles (PM10) by alveolar macrophages stimulates the release of polymorphonuclear leukocytes from bone marrow publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.155.4.9105091 – volume: 277 start-page: L1067 issue: 6 year: 1999 ident: 10.1016/j.freeradbiomed.2020.01.179_bib35 article-title: Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease publication-title: Am. J. Physiol. – volume: 6 start-page: 1308 issue: 9 year: 1993 ident: 10.1016/j.freeradbiomed.2020.01.179_bib49 article-title: Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide publication-title: Eur. Respir. J. doi: 10.1183/09031936.93.06091308 – volume: 9 start-page: 72 issue: 1 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib74 article-title: Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro publication-title: J. Immunot. doi: 10.3109/1547691X.2011.629638 – volume: 49 start-page: 353 issue: 2 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib76 article-title: The environmental sensor AHR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity publication-title: Immunity doi: 10.1016/j.immuni.2018.07.010 – volume: 5 start-page: 605 issue: 6 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib114 article-title: The alveolar macrophages in asthma: a double-edged sword publication-title: Mucosal Immunol. doi: 10.1038/mi.2012.74 – volume: 131 start-page: 465 issue: 4 year: 2009 ident: 10.1016/j.freeradbiomed.2020.01.179_bib83 article-title: Phagocytic leukocytes and reactive oxygen species publication-title: Histochem. Cell Biol. doi: 10.1007/s00418-009-0565-5 – volume: 110 start-page: 1670 issue: 12 year: 2004 ident: 10.1016/j.freeradbiomed.2020.01.179_bib95 article-title: Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters publication-title: Circulation doi: 10.1161/01.CIR.0000142053.13921.21 – volume: 2 start-page: 715 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib103 article-title: Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases publication-title: Redox Biol. doi: 10.1016/j.redox.2014.05.004 – volume: 39 start-page: 147 issue: 1 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib108 article-title: Common ragweed (Ambrosia artemisiifolia L.): allergenicity and molecular characterization of pollen after plant exposure to elevated NO2 publication-title: Plant Cell Environ. doi: 10.1111/pce.12601 – volume: 190 start-page: 1190 issue: 10 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib153 article-title: Proximity to a major road, vitamin D insufficiency, and severe asthma exacerbations in Puerto Rican children publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201408-1568LE – volume: 121 start-page: 1357 issue: 11–12 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib135 article-title: Air pollution exposure and lung function in children: the ESCAPE project publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1306770 – volume: 37 start-page: 706 issue: 6 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib63 article-title: Diesel-enriched particulate matter functionally activates human dendritic cells publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2007-0199OC – volume: 10 start-page: 343 issue: 3 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib29 article-title: What are the biological and therapeutic implications of biomolecule corona formation on the surface of inhaled nanomedicines? publication-title: Nanomedicine (Lond.) doi: 10.2217/nnm.15.2 – volume: 199 start-page: 581 issue: 5 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib122 article-title: Increased chronic obstructive pulmonary disease exacerbations of likely viral etiology follow elevated ambient nitrogen oxides publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201712-2506OC – volume: 159 start-page: 702 issue: 3 year: 1999 ident: 10.1016/j.freeradbiomed.2020.01.179_bib86 article-title: Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.159.3.9709083 – volume: 370 start-page: 20140049 issue: 1661 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib38 article-title: Nanoparticles modulate surfactant protein A and D mediated protection against influenza A infection in vitro publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. doi: 10.1098/rstb.2014.0049 – volume: 599–600 start-page: 291 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib107 article-title: Effect of O3 and NO2 atmospheric pollutants on Platanus x acerifolia pollen: immunochemical and spectroscopic analysis publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2017.04.206 – volume: 136 start-page: 628 issue: 3 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib79 article-title: Distinct endotypes of steroid-resistant asthma characterized by IL-17A and IFN-gamma immunophenotypes: potential benefits of calcitriol publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2015.01.026 – volume: 73 start-page: 418 issue: 5 year: 1995 ident: 10.1016/j.freeradbiomed.2020.01.179_bib91 article-title: Bronchial responsiveness, eosinophilia, and short term exposure to air pollution publication-title: Arch. Dis. Child. doi: 10.1136/adc.73.5.418 – volume: 200 start-page: 523 issue: 5 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib6 article-title: Traffic-related air pollution, health, and allergy: the role of nitrogen dioxide publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201904-0834ED – volume: 12 start-page: 1857 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib102 article-title: Th17 profile in COPD exacerbations publication-title: Int. J. Chronic Obstr. Pulm. Dis. doi: 10.2147/COPD.S136592 – volume: 164 start-page: 819 issue: 5 year: 2001 ident: 10.1016/j.freeradbiomed.2020.01.179_bib32 article-title: Effect of antioxidant supplementation on ozone-induced lung injury in human subjects publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.164.5.2008003 – volume: 56 start-page: 839 issue: 5 year: 1989 ident: 10.1016/j.freeradbiomed.2020.01.179_bib47 article-title: The major human rhinovirus receptor is ICAM-1 publication-title: Cell doi: 10.1016/0092-8674(89)90688-0 – volume: 57 start-page: 79 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib104 article-title: Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2012.11.006 – volume: 28 start-page: S54 issue: Suppl 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib110 article-title: Air pollution as a potential determinant of rheumatoid arthritis: a population-based cohort study in taiwan publication-title: Epidemiology doi: 10.1097/EDE.0000000000000732 – volume: 12 start-page: 1033 issue: 4 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib37 article-title: Enrichment of immunoregulatory proteins in the biomolecular corona of nanoparticles within human respiratory tract lining fluid publication-title: Nanomedicine doi: 10.1016/j.nano.2015.12.369 – volume: 4 start-page: 75 issue: 2 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib133 article-title: Air pollutants and early origins of respiratory diseases publication-title: Chronic Dis. Transl. Med. – volume: 13 issue: 8 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib154 article-title: Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter publication-title: PloS One doi: 10.1371/journal.pone.0200040 – volume: 94 start-page: 1167 issue: 6 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib9 article-title: Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation publication-title: J. Leukoc. Biol. doi: 10.1189/jlb.0313153 – volume: 118 start-page: 120 issue: 1 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib41 article-title: Baseline repeated measures from controlled human exposure studies: associations between ambient air pollution exposure and the systemic inflammatory biomarkers IL-6 and fibrinogen publication-title: Environ. Health Perspect. doi: 10.1289/ehp.0900550 – volume: 95 start-page: 3071 year: 1998 ident: 10.1016/j.freeradbiomed.2020.01.179_bib61 article-title: Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns publication-title: Proc. Natl. Acad. Sci. U. S. A doi: 10.1073/pnas.95.6.3071 – volume: 8 start-page: 19 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib142 article-title: Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice publication-title: Part. Fibre Toxicol. doi: 10.1186/1743-8977-8-19 – volume: 8 start-page: 1781 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib97 article-title: Granulocytes: new members of the antigen-presenting cell family publication-title: Front. Immunol. doi: 10.3389/fimmu.2017.01781 – volume: 190 start-page: 1373 issue: 12 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib116 article-title: IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201406-1039OC – volume: 60 start-page: 504 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib85 article-title: Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter publication-title: Atmos. Environ. doi: 10.1016/j.atmosenv.2012.06.039 – volume: 70 start-page: 341 issue: 5 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib34 article-title: Acute nasal pro-inflammatory response to air pollution depends on characteristics other than particle mass concentration or oxidative potential: the RAPTES project publication-title: Occup. Environ. Med. doi: 10.1136/oemed-2012-100993 – volume: 35 start-page: 1039 issue: 5 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib113 article-title: Defective macrophage phagocytosis of bacteria in COPD publication-title: Eur. Respir. J. doi: 10.1183/09031936.00036709 – volume: 453 start-page: 65 issue: 7191 year: 2008 ident: 10.1016/j.freeradbiomed.2020.01.179_bib23 article-title: Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor publication-title: Nature doi: 10.1038/nature06880 – volume: 15 start-page: 1 issue: 1 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib4 article-title: Composition of air pollution particles and oxidative stress in cells, tissues, and living systems publication-title: J. Toxicol. Environ. Health B Crit. Rev. doi: 10.1080/10937404.2012.632359 – volume: 192 start-page: 1052 issue: 9 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib127 article-title: Prenatal particulate air pollution and asthma onset in urban children. Identifying sensitive windows and sex differences publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201504-0658OC – volume: 7 start-page: 284ra60 issue: 284 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib16 article-title: Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.aaa0282 – volume: 21 start-page: 933 issue: 11 year: 2009 ident: 10.1016/j.freeradbiomed.2020.01.179_bib31 article-title: Antioxidant responses to acute ozone challenge in the healthy human airway publication-title: Inhal. Toxicol. doi: 10.1080/08958370802603789 – volume: 54 start-page: 250 issue: 2 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib68 article-title: Urban particulate matter-activated human dendritic cells induce the expansion of potent inflammatory Th1, Th2 and Th17 effector cells publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2015-0084OC – volume: 10 start-page: 3866 issue: 1 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib124 article-title: Ambient black carbon particles reach the fetal side of human placenta publication-title: Nat. Commun. doi: 10.1038/s41467-019-11654-3 – volume: 24 start-page: 1993 issue: 7 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib20 article-title: Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species publication-title: Toxicol. Vitro : Int. J. Publ. Assoc. BIBRA doi: 10.1016/j.tiv.2010.08.017 – volume: 10 start-page: 369 issue: 3 year: 1988 ident: 10.1016/j.freeradbiomed.2020.01.179_bib54 article-title: Possible mechanisms to explain dust overloading of the lungs publication-title: Fund. Appl. Toxicol. doi: 10.1016/0272-0590(88)90284-9 – volume: 105 start-page: 2412 issue: 11 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib141 article-title: The inflammatory bowel diseases and ambient air pollution: a novel association publication-title: Am. J. Gastroenterol. doi: 10.1038/ajg.2010.252 – volume: 57 start-page: 59 issue: 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib93 article-title: Airborne particulate matter induces nonallergic eosinophilic sinonasal inflammation in mice publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2016-0351OC – volume: 184 start-page: 662 issue: 6 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib121 article-title: Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201104-0597OC – volume: 70 start-page: 910 issue: 8 year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib115 article-title: Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells publication-title: Allergy doi: 10.1111/all.12627 – volume: 153 start-page: 1031 issue: 11 year: 2001 ident: 10.1016/j.freeradbiomed.2020.01.179_bib18 article-title: Health effects of dioxin exposure: a 20-year mortality study publication-title: Am. J. Epidemiol. doi: 10.1093/aje/153.11.1031 – volume: 28 start-page: 147 issue: 2 year: 2008 ident: 10.1016/j.freeradbiomed.2020.01.179_bib67 article-title: Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin publication-title: J. Clin. Immunol. doi: 10.1007/s10875-007-9149-0 – volume: 354 start-page: 482 issue: 9177 year: 1999 ident: 10.1016/j.freeradbiomed.2020.01.179_bib8 article-title: Altered lung antioxidant status in patients with mild asthma publication-title: Lancet doi: 10.1016/S0140-6736(99)01812-7 – volume: 276 start-page: L289 issue: 2 year: 1999 ident: 10.1016/j.freeradbiomed.2020.01.179_bib30 article-title: Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids publication-title: Am. J. Physiol. – volume: 126 start-page: 845 issue: 4 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib101 article-title: Ambient air pollution impairs regulatory T-cell function in asthma publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2010.08.008 – volume: 59 start-page: 189 issue: 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib148 article-title: Combustion-derived nanoparticles in key brain target cells and organelles in young urbanites: culprit hidden in plain sight in alzheimer's disease development publication-title: J. Alzheim. Dis. doi: 10.3233/JAD-170012 – volume: 159 start-page: 536 issue: 2 year: 1999 ident: 10.1016/j.freeradbiomed.2020.01.179_bib90 article-title: Persistent airway inflammation but accommodated antioxidant and lung function responses after repeated daily exposure to nitrogen dioxide publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/ajrccm.159.2.9711068 – volume: 115 start-page: 403 issue: 3 year: 1977 ident: 10.1016/j.freeradbiomed.2020.01.179_bib50 article-title: Fate and distribution of inhaled nitrogen dioxide in rhesus monkeys publication-title: Am. Rev. Respir. Dis. – volume: 200 start-page: 565 issue: 5 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib5 article-title: Particle depletion does not remediate acute effects of traffic-related air pollution and allergen. A randomized, double-blind crossover study publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201809-1657OC – volume: 176 start-page: 7431 year: 2006 ident: 10.1016/j.freeradbiomed.2020.01.179_bib66 article-title: Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation publication-title: J. Immunol. doi: 10.4049/jimmunol.176.12.7431 – volume: 153 start-page: 502 issue: 4 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib65 article-title: Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD8 T lymphocytes publication-title: Immunology doi: 10.1111/imm.12852 – volume: 39 start-page: 141 year: 2019 ident: 10.1016/j.freeradbiomed.2020.01.179_bib123 article-title: Childhood asthma inception and progression: role of microbial exposures, susceptibility to viruses and early allergic sensitization publication-title: Immunol. Allergy Clin. – volume: 140 start-page: 1 issue: 1 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib125 article-title: Environmental determinants of allergy and asthma in early life publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2017.05.010 – volume: 198 start-page: 1413 issue: 11 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib151 article-title: Ambient pollution-related reprogramming of the human small airway epithelial transcriptome publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201712-2526OC – volume: 8 start-page: 166 issue: 2 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib1 article-title: Clearing the air: a review of the effects of particulate matter air pollution on human health publication-title: J. Med. Toxicol. doi: 10.1007/s13181-011-0203-1 – volume: 117 start-page: 2952 issue: 10 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib42 article-title: Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway publication-title: J. Clin. Invest. doi: 10.1172/JCI30639 – volume: 194 start-page: 1475 issue: 12 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib126 article-title: Early-life exposure to the Great smog of 1952 and the development of asthma publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201603-0451OC – volume: 41 start-page: 14 issue: 1 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib58 article-title: Macrophage activation and polarization: nomenclature and experimental guidelines publication-title: Immunity doi: 10.1016/j.immuni.2014.06.008 – volume: 141 start-page: 1074 issue: 3 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib147 article-title: Mechanistic link between diesel exhaust particles and respiratory reflexes publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2017.04.038 – volume: 101 start-page: 1140 issue: 6 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib88 article-title: Ozone enhances the airway inflammation initiated by diesel exhaust publication-title: Respir. Med. doi: 10.1016/j.rmed.2006.11.010 – volume: 70 start-page: 426 issue: 6 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib80 article-title: The biological effects of individual-level PM(2.5) exposure on systemic immunity and inflammatory response in traffic policemen publication-title: Occup. Environ. Med. doi: 10.1136/oemed-2012-100864 – volume: 27 start-page: 34 year: 2002 ident: 10.1016/j.freeradbiomed.2020.01.179_bib26 article-title: Interaction of alveolar macrophages and airway epithelial cells following exposure to particulate matter produces mediators that stimulate the bone marrow publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/ajrcmb.27.1.4787 – volume: 143 start-page: 83 issue: Pt A year: 2015 ident: 10.1016/j.freeradbiomed.2020.01.179_bib130 article-title: Early life exposure to ambient air pollution and childhood asthma in China publication-title: Environ. Res. doi: 10.1016/j.envres.2015.09.032 – volume: 118 start-page: 284 issue: 2 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib129 article-title: Effect of early life exposure to air pollution on development of childhood asthma publication-title: Environ. Health Perspect. doi: 10.1289/ehp.0900916 – volume: 6 start-page: 272 issue: 3 year: 2009 ident: 10.1016/j.freeradbiomed.2020.01.179_bib138 article-title: The origins of asthma and chronic obstructive pulmonary disease in early life publication-title: Proc. Am. Thorac. Soc. doi: 10.1513/pats.200808-092RM – volume: 39 start-page: 372 issue: 2 year: 2013 ident: 10.1016/j.freeradbiomed.2020.01.179_bib22 article-title: Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22 publication-title: Immunity doi: 10.1016/j.immuni.2013.08.003 – volume: 325 start-page: 95 issue: Pt 1 year: 1997 ident: 10.1016/j.freeradbiomed.2020.01.179_bib33 article-title: Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid publication-title: Biochem. J. doi: 10.1042/bj3250095 – volume: 60 start-page: 892 issue: 11 year: 2002 ident: 10.1016/j.freeradbiomed.2020.01.179_bib46 article-title: Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways publication-title: Occup. Environ. Med. doi: 10.1136/oem.60.11.892 – volume: 9 start-page: 334 issue: 2 year: 1996 ident: 10.1016/j.freeradbiomed.2020.01.179_bib36 article-title: Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress publication-title: Eur. Respir. J. doi: 10.1183/09031936.96.09020334 – volume: 20 start-page: 399 issue: 4 year: 2008 ident: 10.1016/j.freeradbiomed.2020.01.179_bib24 article-title: Effects of particulate matter on cytokine production in vitro: a comparative analysis of published studies publication-title: Inhal. Toxicol. doi: 10.1080/08958370801903784 – volume: 12 issue: 3 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib119 article-title: Effect of outdoor air pollution on asthma exacerbations in children and adults: systematic review and multilevel meta-analysis publication-title: PloS One doi: 10.1371/journal.pone.0174050 – volume: 153 start-page: 1229 issue: 5 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib152 article-title: Vitamin D in asthma: mechanisms of action and considerations for clinical trials publication-title: Chest doi: 10.1016/j.chest.2017.09.005 – volume: 11 start-page: 6 issue: 4 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib99 article-title: Immunological features of chronic obstructive pulmonary disease (COPD) induced by indoor pollution and cigarette smoke publication-title: Tanaffos – volume: 17 start-page: 495 issue: 8 year: 2017 ident: 10.1016/j.freeradbiomed.2020.01.179_bib131 article-title: Unique aspects of the perinatal immune system publication-title: Nat. Rev. Immunol. doi: 10.1038/nri.2017.54 – volume: 109 start-page: 250 year: 2003 ident: 10.1016/j.freeradbiomed.2020.01.179_bib25 article-title: Particulate air pollutants and asthma - a paradigm for the role of oxidative stress in PM-induced adverse health effects publication-title: Clin. Immunol. doi: 10.1016/j.clim.2003.08.006 – volume: 376 start-page: 826 issue: 9743 year: 2010 ident: 10.1016/j.freeradbiomed.2020.01.179_bib111 article-title: Role of viral respiratory infections in asthma and asthma exacerbations publication-title: Lancet doi: 10.1016/S0140-6736(10)61380-3 – volume: 11 start-page: 87 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib132 article-title: Maternal exposure to air pollution before and during pregnancy related to changes in newborn's cord blood lymphocyte subpopulations. The EDEN study cohort publication-title: BMC Pregnancy Childbirth doi: 10.1186/1471-2393-11-87 – volume: 275 start-page: C1 year: 1998 ident: 10.1016/j.freeradbiomed.2020.01.179_bib14 article-title: Interaction of reactive oxygen species with ion transport mechanisms publication-title: Am. J. Physiol. doi: 10.1152/ajpcell.1998.275.1.C1 – volume: 6 issue: 1 year: 2011 ident: 10.1016/j.freeradbiomed.2020.01.179_bib55 article-title: Traffic air pollution and oxidized LDL publication-title: PloS One doi: 10.1371/journal.pone.0016200 – volume: 62 start-page: 355 issue: 6 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib84 article-title: The London Underground: dust and hazards to health publication-title: Occup. Environ. Med. doi: 10.1136/oem.2004.014332 – volume: 151 start-page: 458 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib117 article-title: Panel studies of air pollution in patients with COPD: systematic review and meta-analysis publication-title: Environ. Res. doi: 10.1016/j.envres.2016.08.018 – volume: 45 start-page: 963 issue: 5 year: 2016 ident: 10.1016/j.freeradbiomed.2020.01.179_bib39 article-title: GM-CSF: From growth factor to central mediator of tissue inflammation publication-title: Immunity doi: 10.1016/j.immuni.2016.10.026 – volume: 48 start-page: 1665 issue: 12 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib44 article-title: IL-33 signalling contributes to pollutant-induced allergic airway inflammation publication-title: Clin. Exp. Allergy doi: 10.1111/cea.13261 – volume: 46 start-page: 9062 issue: 16 year: 2012 ident: 10.1016/j.freeradbiomed.2020.01.179_bib28 article-title: In vitro exposures in diesel exhaust atmospheres: resuspension of PM from filters versus direct deposition of PM from air publication-title: Environ. Sci. Technol. doi: 10.1021/es301431s – volume: 5 start-page: 953 issue: 12 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib57 article-title: Monocyte and macrophage heterogeneity publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1733 – volume: 50 start-page: 281 issue: 2 year: 2014 ident: 10.1016/j.freeradbiomed.2020.01.179_bib64 article-title: Urban particulate matter suppresses priming of Th1 cells by GM-CSF-activated human dendritic cells publication-title: Am. J. Respir. Cell Mol. Biol. doi: 10.1165/rcmb.2012-0465OC – volume: 38 start-page: 995 year: 2005 ident: 10.1016/j.freeradbiomed.2020.01.179_bib12 article-title: Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses publication-title: Braz. J. Med. Biol. Res. doi: 10.1590/S0100-879X2005000700003 – volume: 292 start-page: L1444 issue: 6 year: 2007 ident: 10.1016/j.freeradbiomed.2020.01.179_bib15 article-title: The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists publication-title: Am. J. Physiol. Lung Cell Mol. Physiol. doi: 10.1152/ajplung.00162.2006 – volume: 376 start-page: 445 issue: 3 year: 2008 ident: 10.1016/j.freeradbiomed.2020.01.179_bib59 article-title: Functional adaptation to oxidative stress by memory T cells: an analysis of the role in the cardiovascular disease process publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2008.09.038 – volume: 6 issue: 18 year: 2018 ident: 10.1016/j.freeradbiomed.2020.01.179_bib81 article-title: Ambient particulate matter enhances the pulmonary allergic immune response to house dust mite in a BALB/c mouse model by augmenting Th2- and Th17-immune responses publication-title: Phys. Rep. – volume: 15 start-page: S55 issue: 4 year: 2004 ident: 10.1016/j.freeradbiomed.2020.01.179_bib92 article-title: Exposure to air pollution from heavy traffic is associated with increased eosinophilic activation in Dutch schoolchildren publication-title: Epidemiology doi: 10.1097/00001648-200407000-00160 |
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| SubjectTerms | Air Pollutants - toxicity Air Pollution - adverse effects Air Pollution - analysis Asthma Asthma - etiology COPD Dendritic cell Humans Immune System Infant, Newborn Lymphocyte Macrophage Oxidative stress Particulate matter Particulate Matter - analysis Particulate Matter - toxicity Pulmonary Disease, Chronic Obstructive Respiratory virus |
| Title | Air pollution and its effects on the immune system |
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