NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

NFATc2 -rearranged sarcomas ( NFATc2 -Sarcomas) are infrequent round cell tumors characterized by EWSR1-NFATc2 fusions and FUS-NFATc2 fusions. Although our knowledge on these neoplasms has increased recently, novel diagnostic tools and more comprehensive series are still needed. Here, we describe th...

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Veröffentlicht in:	Modern pathology Jg. 33; H. 10; S. 1930 - 1944
Hauptverfasser:	Perret, Raul, Escuriol, Julien, Velasco, Valérie, Mayeur, Laetitia, Soubeyran, Isabelle, Delfour, Christophe, Aubert, Sébastien, Polivka, Marc, Karanian, Marie, Meurgey, Alexandra, Le Guellec, Sophie, Weingertner, Noelle, Hoeller, Sylvia, Coindre, Jean-Michel, Larousserie, Frédérique, Pierron, Gaëlle, Tirode, Franck, Le Loarer, François
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Nature Publishing Group US 01.10.2020 Elsevier Limited Nature Publishing Group: Open Access Hybrid Model Option B
Schlagworte:	13/51 14/32 14/63 38/39 38/43 38/91 692/699/67/1344 692/699/67/1798 Adult Aged Aggrecan Aggrecans - metabolism Biomarkers, Tumor - metabolism Bone cancer Bone Neoplasms - diagnosis Bone Neoplasms - genetics Bone Neoplasms - metabolism Bone tumors Cancer CD99 antigen Chemotherapy Chondrosarcoma Cytogenetics Desmin Female Femur FLI-1 protein Humans Ilium Immunohistochemistry Karyotypes Keratin Laboratory Medicine Life Sciences Male Medical diagnosis Medicine Medicine & Public Health Mesenchyme Middle Aged Neoplasia NFATC Transcription Factors - genetics Oncogene Fusion Oncogene Proteins, Fusion - genetics Osteoid Pathology Patients Pleomorphism Sarcoma Sarcoma - diagnosis Sarcoma - genetics Sarcoma - metabolism Soft tissues Stroma Surgery Tibia Tumor suppressor genes Tumors
ISSN:	0893-3952, 1530-0285, 1530-0285
Online-Zugang:	Volltext
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