Persistently expressed human chorionic gonadotropin induces premature luteinization and progressive alterations on the reproductive axis in female mice

•Elevated human chorionic gonadotropin hormone (hCG) induced female infertility.•A progressive impairment of the reproductive function occurred from peripuberty.•Persistently elevated levels of hCG induced prolactin synthesis and secretion.•Elevated hCG and prolactin induced premature luteinization...

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Vydáno v:	General and comparative endocrinology Ročník 336; s. 114247
Hlavní autoři:	Marcial Lopez, Agustina, Ratner, Laura D., Martinez, Carolina S., Di Giorgio, Noelia, Poutanen, Matti, Huhtaniemi, Ilpo T., Rulli, Susana B.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 15.05.2023
Témata:	Animals beta Subunit Chorionic Gonadotropin Chorionic Gonadotropin - pharmacology Chorionic Gonadotropin, beta Subunit, Human - genetics Chorionic Gonadotropin, beta Subunit, Human - metabolism Endocrinology and Diabetes Endokrinologi och diabetes Female Female reproduction genetics Human Human chorionic gonadotropin Humans Infertility Luteinization Mammals Mammals - metabolism metabolism Mice Mice, Transgenic Ovary pharmacology Premature luteinization Prolactin Transgenic Transgenic mice Premature luteinization Ovary Female reproduction Prolactin Human chorionic gonadotropin Transgenic mice
ISSN:	0016-6480, 1095-6840, 1095-6840
On-line přístup:	Získat plný text
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