Role of the NLRP1 inflammasome in skin cancer and inflammatory skin diseases

Inflammasomes are cytoplasmic protein complexes that play a crucial role in protecting the host against pathogenic and sterile stressors by initiating inflammation. Upon activation, these complexes directly regulate the proteolytic processing and activation of proinflammatory cytokines interleukin (...

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Veröffentlicht in:	British Journal of Dermatology Jg. 190; H. 3; S. 305 - 315
Hauptverfasser:	Calabrese, Laura, Fiocco, Zeno, Mellett, Mark, Aoki, Rui, Rubegni, Pietro, French, Lars E, Satoh, Takashi K
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press (OUP) 16.02.2024 Oxford University Press
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Addison's disease Apoptosis Apoptosis Regulatory Proteins - metabolism Atopic dermatitis Autoimmune diseases Caspase Cell death Cellular stress response Dermatitis Dyskeratosis Humans Immune system Inflammasomes Inflammation - genetics Inflammatory diseases Interleukin-1beta - metabolism Keratinocytes Keratosis Melanoma NLR Proteins - metabolism Pemphigus Proteolysis Psoriasis Pyrin protein Pyroptosis Sarcoma Skin cancer Skin diseases Skin Diseases - etiology Skin Neoplasms - pathology Squamous cell carcinoma Systemic lupus erythematosus Vitiligo
ISSN:	0007-0963, 1365-2133, 1365-2133
Online-Zugang:	Volltext
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