Exploring immune activation patterns in HER2-low and HER2-ultralow breast cancer subtypes

Abstract Background A deeper understanding of the molecular and clinical characteristics of HER2-low and ultralow breast cancer (BC) subtypes is essential for advancing therapeutic strategies. Methods Three independent GEO datasets with microarray and IHC/FISH data from 510 BC patients were analyzed...

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Bibliographic Details
Published in:	The oncologist (Dayton, Ohio) Vol. 30; no. 6
Main Authors:	Munkácsy, Gyöngyi, Santarpia, Libero, Győrffy, Balázs
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 01.06.2025
Subjects:	Breast Cancer Breast Neoplasms - genetics Breast Neoplasms - immunology Breast Neoplasms - pathology Cancer Development and progression Diagnosis Female Gene expression Genetic aspects Health aspects Humans Immune response Middle Aged Oncology, Experimental Prognosis Receptor, ErbB-2 - genetics Receptor, ErbB-2 - immunology Receptor, ErbB-2 - metabolism Hungary immune landscape biomarker anti-HER2 therapies HER2-ultralow gene expression ERBB2
ISSN:	1083-7159, 1549-490X, 1549-490X
Online Access:	Get full text
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