Net benefit in the presence of correlated prioritized outcomes using generalized pairwise comparisons: A simulation study

Background The prioritized net benefit (Δ) is a measure of the benefit‐risk balance in clinical trials, based on generalized pairwise comparisons (GPC) using several prioritized outcomes. Its estimation requires the classification as Wins or Losses of all possible pairs of patients, one from the exp...

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Veröffentlicht in:	Statistics in medicine Jg. 40; H. 3; S. 553 - 565
Hauptverfasser:	Giai, Joris, Maucort‐Boulch, Delphine, Ozenne, Brice, Chiêm, Jean‐Christophe, Buyse, Marc, Péron, Julien
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 10.02.2021 Wiley Subscription Services, Inc Wiley-Blackwell
Schlagworte:	clinical trial Clinical trials Computer Science correlation generalized pairwise comparisons Mathematics multivariate analysis net benefit Statistics clinical trial correlation net benefit generalized pairwise comparisons multivariate analysis
ISSN:	0277-6715, 1097-0258, 1097-0258
Online-Zugang:	Volltext
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