Regulation of peptide‐chain elongation in mammalian cells

The elongation phase of mRNA translation is the stage at which the polypeptide is assembled and requires a substantial amount of metabolic energy. Translation elongation in mammals requires a set of nonribosomal proteins called eukaryotic elongation actors or eEFs. Several of these proteins are subj...

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Veröffentlicht in:	European journal of biochemistry Jg. 269; H. 22; S. 5360 - 5368
Hauptverfasser:	Browne, Gareth J., Proud, Christopher G.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Oxford, UK Blackwell Science Ltd 01.11.2002
Schlagworte:	Animals calcium calmodulin Cell Line Cyclic AMP-Dependent Protein Kinases - metabolism eEF1 eEF2 elongation factor energy Humans Insulin - metabolism ions mammals messenger RNA mitogen-activated protein kinase mitogen-activated protein kinase kinase Models, Biological Models, Genetic mTOR Peptide Elongation Factor 1 - chemistry Peptide Elongation Factor 1 - metabolism Peptide Elongation Factor 2 - chemistry Peptide Elongation Factor 2 - metabolism Phosphorylation polypeptides Protein Biosynthesis Protein Structure, Tertiary protein synthesis rapamycin ribosomes RNA, Messenger - metabolism signal transduction translation translation (genetics)
ISSN:	0014-2956, 1432-1033
Online-Zugang:	Volltext
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