MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer

Standard-of-care for resectable gastric/gastroesophageal junction cancer includes surgery and neoadjuvant-adjuvant 5-fluorouracil-leucovorin-oxaliplatin-docetaxel (FLOT) chemotherapy. Early-phase clinical studies support further clinical development of the immune checkpoint inhibitor (ICI); durvalum...

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Veröffentlicht in:	Future oncology (London, England) Jg. 18; H. 20; S. 2465
Hauptverfasser:	Janjigian, Yelena Y, Van Cutsem, Eric, Muro, Kei, Wainberg, Zev, Al-Batran, Salah-Eddin, Hyung, Woo Jin, Molena, Daniela, Marcovitz, Michelle, Ruscica, Dario, Robbins, Scott H, Negro, Alejandra, Tabernero, Josep
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.06.2022
Schlagworte:	Adenocarcinoma - pathology Antibodies, Monoclonal Antineoplastic Combined Chemotherapy Protocols - adverse effects Clinical Trials, Phase III as Topic Esophagogastric Junction - pathology Fluorouracil - adverse effects Humans Neoadjuvant Therapy Randomized Controlled Trials as Topic Stomach Neoplasms - pathology neoadjuvant-adjuvant resectable durvalumab gastric cancer immunotherapy PD-L1 gastroesophageal junction cancer immune checkpoint inhibitors chemotherapy
ISSN:	1744-8301, 1744-8301
Online-Zugang:	Weitere Angaben
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