Iron Deficiency Caused by Intestinal Iron Loss—Novel Candidate Genes for Severe Anemia

The adult human body contains about 4 g of iron. About 1–2 mg of iron is absorbed every day, and in healthy individuals, the same amount is excreted. We describe a patient who presents with severe iron deficiency anemia with hemoglobin levels below 6 g/dL and ferritin levels below 30 ng/mL. Although...

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Bibliographic Details
Published in:	Genes Vol. 12; no. 12; p. 1869
Main Authors:	Huettmann, Carolina, Stelljes, Matthias, Sivalingam, Sugirthan, Fobker, Manfred, Vrachimis, Alexis, Exler, Anne, Wenning, Christian, Wempe, Carola, Penke, Matthias, Buness, Andreas, Ludwig, Kerstin U., Muckenthaler, Martina U., Steinbicker, Andrea U.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 24.11.2021 MDPI
Subjects:	Aged Aged, 80 and over Anemia Anemia, Iron-Deficiency - blood Anemia, Iron-Deficiency - etiology Anemia, Iron-Deficiency - genetics Biopsy Bleeding Blood Bone marrow Chronic illnesses Cytokines diagnostic techniques Erythrocytes Erythropoiesis Erythropoiesis - genetics Excretion Families & family life Feces Female Ferritin Gastrointestinal Tract - metabolism Genetic diversity Genetic Variation - genetics Graphite Hemoglobin Hemorrhage - complications Hemorrhage - genetics Heredity Humans Intestine intestines Intravenous administration intravenous injection Iron Iron - blood Iron - metabolism Iron - urine Iron Deficiencies - etiology Iron Deficiencies - genetics Iron deficiency iron deficiency anemia liver Magnetic resonance imaging Male Middle Aged Mutation Mutation - genetics Nutrient deficiency Patients Plasma probability urine Germany genetically caused iron imbalance iron erythropoiesis intestinal iron loss red cells
ISSN:	2073-4425, 2073-4425
Online Access:	Get full text
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