Lack of butyrate is associated with induction of Bax and subsequent apoptosis in the proximal colon of guinea pig

Butyrate stimulates proliferation and suppresses differentiation in normal colonic epithelial cells. Because the involved intracellular signaling mechanisms are unclear, this study investigated certain molecular effects of butyrate. Tissue sheets from guinea pig proximal colon were incubated in Ussi...

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Vydané v:	Gastroenterology (New York, N.Y. 1943) Ročník 112; číslo 3; s. 875
Hlavní autori:	Hass, R, Busche, R, Luciano, L, Reale, E, Engelhardt, W V
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.1997
Predmet:	Animals Apoptosis bcl-2-Associated X Protein Butyrates - analysis Butyrates - pharmacology Butyric Acid Cell Division - drug effects Colon - chemistry Colon - pathology Colon - ultrastructure DNA Fragmentation Guinea Pigs Male Proto-Oncogene Proteins - analysis Proto-Oncogene Proteins c-bcl-2
ISSN:	0016-5085
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