First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening

Down's syndrome occurs when a person has three, rather than two copies of chromosome 21; or the specific area of chromosome 21 implicated in causing Down's syndrome. It is the commonest congenital cause of mental disability and also leads to numerous metabolic and structural problems. It c...

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Bibliographic Details
Published in:	Cochrane database of systematic reviews Vol. 3; p. CD012600
Main Authors:	Alldred, S Kate, Takwoingi, Yemisi, Guo, Boliang, Pennant, Mary, Deeks, Jonathan J, Neilson, James P, Alfirevic, Zarko
Format:	Journal Article
Language:	English
Published:	England 15.03.2017
Subjects:	Biomarkers - blood Chorionic Gonadotropin - blood Chorionic Gonadotropin, beta Subunit, Human - blood Down Syndrome - blood Down Syndrome - diagnosis Down Syndrome - diagnostic imaging False Positive Reactions Female Humans Maternal Age Nasal Bone - diagnostic imaging Pregnancy Pregnancy Trimester, First - blood Pregnancy-Associated Plasma Protein-A - analysis Sensitivity and Specificity Ultrasonography, Prenatal
ISSN:	1469-493X, 1469-493X
Online Access:	Get more information
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