In vivo glia‐to‐neuron conversion: pitfalls and solutions

Neuron loss and disruption of neural circuits are associated with many neurological conditions. A key question is how to rebuild neural circuits for functional improvements. In vivo glia‐to‐neuron (GtN) conversion emerges as a potential solution for regeneration‐based therapeutics. This approach tak...

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Vydané v:	Developmental neurobiology (Hoboken, N.J.) Ročník 82; číslo 5; s. 367 - 374
Hlavní autori:	Wang, Lei‐Lei, Zhang, Chun‐Li
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Wiley Subscription Services, Inc 01.07.2022
Predmet:	BrdU Cell Differentiation Cell fate Cellular Reprogramming Functional morphology Glial cells glia‐to‐neuron (GtN) conversion Humans in vivo reprogramming lineage tracing Nerve Degeneration Neural networks NEUROD1 Neuroglia Neuronal-glial interactions Neurons - physiology PTBP1 Regeneration NEUROD1 PTBP1 in vivo reprogramming lineage tracing glia-to-neuron (GtN) conversion BrdU
ISSN:	1932-8451, 1932-846X, 1932-846X
On-line prístup:	Získať plný text
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