BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization

This study focused on resolving the relationship between BMI and type 2 diabetes. The availability of multiple variants associated with BMI offers a new chance to resolve the true causal effect of BMI on type 2 diabetes; however, the properties of these associations and their validity as genetic ins...

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Vydáno v:	Diabetes (New York, N.Y.) Ročník 65; číslo 10; s. 3002 - 3007
Hlavní autoři:	Corbin, Laura J, Richmond, Rebecca C, Wade, Kaitlin H, Burgess, Stephen, Bowden, Jack, Smith, George Davey, Timpson, Nicholas J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.10.2016
Témata:	Body Mass Index Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Genetic Pleiotropy - genetics Genetic Predisposition to Disease - genetics Humans Mendelian Randomization Analysis Odds Ratio Risk Factors Transcription Factor 7-Like 2 Protein - genetics
ISSN:	1939-327X
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