The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

In the 1960s, Christian Anfinsen postulated that the unique three-dimensional structure of a protein is determined by its amino acid sequence. This work laid the foundation for the sequence-structure-function paradigm, which states that the sequence of a protein determines its structure, and structu...

Full description

Saved in:

Bibliographic Details
Published in:	Biochemical Society transactions Vol. 44; no. 5; pp. 1185 - 1200
Main Author:	Babu, M Madan
Format:	Journal Article
Language:	English
Published:	England 15.10.2016
Subjects:	Alternative Splicing Amino Acid Sequence Apoptosis - genetics Disease - genetics Humans Intrinsically Disordered Proteins - chemistry Intrinsically Disordered Proteins - genetics Intrinsically Disordered Proteins - metabolism Models, Molecular Protein Conformation Protein Folding Structure-Activity Relationship protein turnover RNA localization alternative splicing gene expression and regulation intrinsically disordered proteins biological networks
ISSN:	1470-8752
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!