Endothelial response to glucose: dysfunction, metabolism, and transport

The endothelial cell response to glucose plays an important role in both health and disease. Endothelial glucose-induced dysfunction was first studied in diabetic animal models and in cells cultured in hyperglycemia. Four classical dysfunction pathways were identified, which were later shown to resu...

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Bibliographic Details
Published in:	Biochemical Society transactions Vol. 49; no. 1; p. 313
Main Author:	Clyne, Alisa Morss
Format:	Journal Article
Language:	English
Published:	England 26.02.2021
Subjects:	Animals Biological Transport - drug effects Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - pathology Diabetes Mellitus, Type 2 - physiopathology Endothelial Cells - drug effects Endothelial Cells - metabolism Endothelial Cells - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Endothelium, Vascular - physiopathology Glucose - pharmacology Glycolysis - drug effects Humans Hyperglycemia - metabolism Hyperglycemia - pathology Hyperglycemia - physiopathology Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - physiology blood brain barrier glucose transport extracellular vesicles SGLT2 diabetes glycolysis
ISSN:	1470-8752, 1470-8752
Online Access:	Get more information
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