Structure and function of the cytochrome P450 peroxygenase enzymes

The cytochromes P450 (P450s or CYPs) constitute a large heme enzyme superfamily, members of which catalyze the oxidative transformation of a wide range of organic substrates, and whose functions are crucial to xenobiotic metabolism and steroid transformation in humans and other organisms. The P450 p...

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Bibliographic Details
Published in:	Biochemical Society transactions Vol. 46; no. 1; p. 183
Main Authors:	Munro, Andrew W, McLean, Kirsty J, Grant, Job L, Makris, Thomas M
Format:	Journal Article
Language:	English
Published:	England 19.02.2018
Subjects:	Amino Acid Sequence Biofuels Carboxylic Acids - metabolism Catalysis Catalytic Domain Cytochrome P-450 Enzyme System - chemistry Cytochrome P-450 Enzyme System - metabolism Fatty Acids - metabolism Humans Hydrogen Peroxide - metabolism Hydroxylation Oxidation-Reduction Peroxidases - chemistry Peroxidases - metabolism Structure-Activity Relationship Substrate Specificity iron-oxo species cytochrome P450 alkenes enzyme mechanism peroxygenase substrate decarboxylation
ISSN:	1470-8752, 1470-8752
Online Access:	Get more information
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