Is there a prognostic role of K-ras point mutations in the serum of patients with advanced non-small cell lung cancer?

The purpose of this study was to investigate the prognostic significance of K-ras mutations in circulating DNA in advanced non-small lung cancer (NSCLC) patients. Serum samples were assessed prior to platinum-based chemotherapy start in 67 patients with advanced NSCLC (stage IIIB or IV), treated bet...

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Bibliographic Details
Published in:	Lung cancer (Amsterdam, Netherlands) Vol. 50; no. 3; pp. 339 - 346
Main Authors:	Camps, Carlos, Sirera, Rafael, Bremnes, Roy, Blasco, Ana, Sancho, Eva, Bayo, Pilar, Safont, Maria Jose, Sánchez, José Javier, Tarón, Miquel, Rosell, Rafael
Format:	Journal Article
Language:	English
Published:	Shannon Elsevier Ireland Ltd 01.12.2005 Elsevier Science
Subjects:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Non-Small-Cell Lung - blood Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - genetics Codon Data Interpretation, Statistical DNA, Neoplasm - blood DNA, Neoplasm - genetics Female Gene Amplification Genes, ras Genotype Humans K-ras Lung Neoplasms - blood Lung Neoplasms - diagnosis Lung Neoplasms - genetics Male Medical sciences Middle Aged Molecular markers Non-small cell lung cancer NSCLC Pneumology Point Mutation Prognosis Prognostic factors Sensitivity and Specificity Survival Analysis Tumors of the respiratory system and mediastinum Molecular markers NSCLC K-ras Prognostic factors Non-small cell lung cancer Human Lung disease Prognosis Respiratory disease Lung cancer Non-small celt lung cancer Malignant tumor Molecular marker non-small cell lung carcinoma Point mutation Bronchus disease Serum Onc gene Non small cell carcinoma
ISSN:	0169-5002, 1872-8332
Online Access:	Get full text
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