MSstatsTMT: Statistical Detection of Differentially Abundant Proteins in Experiments with Isobaric Labeling and Multiple Mixtures

Tandem mass tag (TMT) is a multiplexing technology widely-used in proteomic research. It enables relative quantification of proteins from multiple biological samples in a single MS run with high efficiency and high throughput. However, experiments often require more biological replicates or conditio...

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Vydáno v:	Molecular & cellular proteomics Ročník 19; číslo 10; s. 1706
Hlavní autoři:	Huang, Ting, Choi, Meena, Tzouros, Manuel, Golling, Sabrina, Pandya, Nikhil Janak, Banfai, Balazs, Dunkley, Tom, Vitek, Olga
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.10.2020
Témata:	Humans Isotope Labeling Proteome - metabolism Proteomics Statistics as Topic Tandem Mass Spectrometry quantification hypothesis testing protein quantification multiple mixtures mathematical modeling TMT Mass spectrometry bioinformatics software statistics
ISSN:	1535-9484, 1535-9484
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