LRRK2 links genetic and sporadic Parkinson's disease

The past two decades in research has revealed the importance of leucine-rich repeat kinase 2 (LRRK2) in both monogenic and sporadic forms of Parkinson's disease (PD). In families, mutations in LRRK2 can cause PD with age-dependent but variable penetrance and genome-wide association studies have...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical Society transactions Jg. 47; H. 2; S. 651
Hauptverfasser:	Kluss, Jillian H, Mamais, Adamantios, Cookson, Mark R
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 30.04.2019
Schlagworte:	Animals Genome-Wide Association Study - methods Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - genetics Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - metabolism Mutation - genetics Parkinson Disease - enzymology Parkinson Disease - genetics Protein Serine-Threonine Kinases - genetics leucine-rich repeat kinase genome-wide association studies Parkinson's disease
ISSN:	1470-8752, 1470-8752
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!