Imported Dengue Fever in Milan, Italy: A Seven-Year Retrospective Study

Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. Methods: We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed a...

Full description

Saved in:
Bibliographic Details
Published in:Infectious disease reports Vol. 17; no. 5; p. 113
Main Authors: Pieruzzi, Margherita Eleonora, Mileto, Davide, Behring, Alessandra Helen, Caronni, Stefania, Mancon, Alessandro, Vezzosi, Luigi, Rizzo, Alberto, Poloni, Andrea, Gori, Andrea, Giacomelli, Andrea, Antinori, Spinello
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 12.09.2025
Subjects:
Antibodies
Blood
Chikungunya virus
Cross-reactivity
Dengue fever
Dengue hemorrhagic fever
Emergency medical care
Epidemics
Hospitals
Immunization
Immunoglobulin G
Immunoglobulin M
imported
Italy
Laboratories
Leukopenia
Mosquitoes
Myalgia
Pandemics
Patients
Plasma
Polymerase chain reaction
Public health
Real time
Serology
Serotypes
Thrombocytopenia
travelers
Urine
Vector-borne diseases
Viral diseases
warning signs
West Nile virus
Zika virus
Italy
Southeast Asia
Spain
warning signs
Italy
dengue fever
travelers
imported
ISSN:2036-7449, 2036-7430, 2036-7449
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. Methods: We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive. Results: This analysis included 159 travelers with confirmed (n = 138; 86.8%) or probable (n = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30–50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3–6); 29.6% required hospitalization, with a median stay of four days (IQR 0–5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue. Conclusions: Dengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses.
AbstractList Dengue fever is an arboviral infection transmitted by mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive. This analysis included 159 travelers with confirmed ( = 138; 86.8%) or probable ( = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30-50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3-6); 29.6% required hospitalization, with a median stay of four days (IQR 0-5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue. Dengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses.
Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases. Methods: We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive. Results: This analysis included 159 travelers with confirmed (n = 138; 86.8%) or probable (n = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30–50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3–6); 29.6% required hospitalization, with a median stay of four days (IQR 0–5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue. Conclusions: Dengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses.
Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases.BACKGROUNDDengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of autochthonous cases.We retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive.METHODSWe retrospectively retrieved dengue cases in returning travelers from tropical areas diagnosed at the Luigi Sacco Hospital between January 2018 and December 2024. All patients with positive serology for DENV (IgM alone or IgM and IgG or neutralizing antibodies detection) and/or positive real-time polymerase chain reaction (RT-PCR) for DENV RNA on plasma and urine were considered. Analyses were descriptive.This analysis included 159 travelers with confirmed (n = 138; 86.8%) or probable (n = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30-50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3-6); 29.6% required hospitalization, with a median stay of four days (IQR 0-5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue.RESULTSThis analysis included 159 travelers with confirmed (n = 138; 86.8%) or probable (n = 21; 13.2%) dengue fever. The median age was 38 years (interquartile range [IQR] 30-50); 87 (54.7%) were females. The median time between symptom onset and seeking medical attention was four days (IQR 3-6); 29.6% required hospitalization, with a median stay of four days (IQR 0-5). The most common symptoms included fever (100%), myalgia (52.2%), and headache (49.1%). Laboratory findings revealed thrombocytopenia (53.8%), leukopenia (64.1%), elevated ALT (51.9%), and LDH (60.2%). Among the confirmed cases, 128 (92.8%) were diagnosed with RT-PCR. Serotypes 1 and 2 were the most prevalent (28.9% and 27.3%, respectively). Most cases were classified as dengue without warning signs (150, 94.3%), eight cases (5.0%) as dengue with warning signs, and one as severe dengue.Dengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses.CONCLUSIONSDengue fever is an important cause of fever among travelers returning to Italy from endemic areas. Although severe dengue is rare among travelers, further prospective studies need to address this issue. Diagnosis should be pursued by using molecular tools because of cross-reactivity with other arboviruses.
Author Mileto, Davide
Pieruzzi, Margherita Eleonora
Vezzosi, Luigi
Poloni, Andrea
Caronni, Stefania
Giacomelli, Andrea
Rizzo, Alberto
Behring, Alessandra Helen
Mancon, Alessandro
Gori, Andrea
Antinori, Spinello
Author_xml – sequence: 1
  givenname: Margherita Eleonora
  surname: Pieruzzi
  fullname: Pieruzzi, Margherita Eleonora
– sequence: 2
  givenname: Davide
  orcidid: 0000-0002-9414-0287
  surname: Mileto
  fullname: Mileto, Davide
– sequence: 3
  givenname: Alessandra Helen
  surname: Behring
  fullname: Behring, Alessandra Helen
– sequence: 4
  givenname: Stefania
  surname: Caronni
  fullname: Caronni, Stefania
– sequence: 5
  givenname: Alessandro
  orcidid: 0000-0002-1490-636X
  surname: Mancon
  fullname: Mancon, Alessandro
– sequence: 6
  givenname: Luigi
  surname: Vezzosi
  fullname: Vezzosi, Luigi
– sequence: 7
  givenname: Alberto
  orcidid: 0000-0001-5999-006X
  surname: Rizzo
  fullname: Rizzo, Alberto
– sequence: 8
  givenname: Andrea
  surname: Poloni
  fullname: Poloni, Andrea
– sequence: 9
  givenname: Andrea
  orcidid: 0000-0001-6587-4794
  surname: Gori
  fullname: Gori, Andrea
– sequence: 10
  givenname: Andrea
  orcidid: 0000-0003-3685-4289
  surname: Giacomelli
  fullname: Giacomelli, Andrea
– sequence: 11
  givenname: Spinello
  orcidid: 0000-0003-0569-9407
  surname: Antinori
  fullname: Antinori, Spinello
BackLink https://www.ncbi.nlm.nih.gov/pubmed/40981333$$D View this record in MEDLINE/PubMed
BookMark eNpdkU1r3DAQhkVJaT5PvRdBL4HG6UgjS3ZuIU3ShYRC0h56ErI0Dl681ka2A_vvq2bTEDqXGWYeXt6Z2Wc7QxyIsY8CThFr-NqFJAyUIAS-Y3sSUBdGqXrnTb3LjsZxCTmw1srgB7aroK4EIu6x68VqHdNEgX-j4WEmfkVPlHg38Nuud8MJX0yu35zxc36fB0Pxm1zidzSlOK7JT90T8ftpDptD9r51_UhHL_mA_bq6_Hnxvbj5cb24OL8pvFJmKrSkVhpfCdWSKrVvWknCC1dBFZQQ4E1dIgRVGmMq1QA1pUfpnAoE4EvCA7bY6obolnadupVLGxtdZ58bMT1Yl6bO92RDA00IbUAnvWq1dg4kSUIR2kp7I7LW8VZrneLjTONkV93oqc97U5xHizJ7UahMmdHP_6HLOKchb5opXdYCdG0y9emFmpsVhVd7_86dgS9bwOf7jYnaV0SA_ftP--af-AcoUo8c
Cites_doi 10.1016/j.tmaid.2024.102762
10.37573/9781585285495
10.1093/jtm/taaf037
10.1002/rmv.2093
10.1016/j.tmaid.2025.102795
10.4103/ijmr.IJMR_2612_19
10.1007/s15010-025-02476-1
10.7326/M23-0721
10.1016/j.tmaid.2015.06.005
10.3390/ijms26146609
10.1016/j.meegid.2018.11.009
10.2807/1560-7917.ES.2017.22.1.30433
10.1093/jtm/taae089
10.1016/S0140-6736(23)02576-X
10.1111/jtm.12122
10.1093/jtm/taab130
10.1016/S1473-3099(23)00571-6
10.3389/fcimb.2022.975398
10.1002/jmv.29245
10.1093/jtm/taab183
10.1093/oxfordjournals.bmb.a011708
10.1016/j.tmaid.2016.01.007
10.1007/s13149-017-0542-x
10.1093/jtm/taad127
10.1016/j.jiac.2023.01.015
10.4269/ajtmh.17-0866
ContentType Journal Article
Copyright 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID AAYXX
CITATION
NPM
3V.
7X2
7X7
7XB
8C1
8FE
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
ATCPS
AZQEC
BENPR
BHPHI
CCPQU
COVID
DWQXO
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
M0K
M0S
PATMY
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PYCSY
7X8
DOA
DOI 10.3390/idr17050113
DatabaseName CrossRef
PubMed
ProQuest Central (Corporate)
Agricultural Science Collection
ProQuest Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Public Health Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
Agricultural & Environmental Science Collection
ProQuest Central Essentials - QC
ProQuest Central (New)
Natural Science Collection
ProQuest One Community College
Coronavirus Research Database
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Agriculture Science Database
ProQuest Health & Medical Collection
Environmental Science Database
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic (retired)
ProQuest One Academic UKI Edition
ProQuest Central China
Environmental Science Collection
MEDLINE - Academic
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
PubMed
Agricultural Science Database
Publicly Available Content Database
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Health & Medical Research Collection
Agricultural & Environmental Science Collection
ProQuest Central (New)
ProQuest Public Health
ProQuest One Academic Eastern Edition
Agricultural Science Collection
Coronavirus Research Database
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest SciTech Collection
ProQuest Hospital Collection (Alumni)
Environmental Science Collection
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Environmental Science Database
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList PubMed
Agricultural Science Database
CrossRef

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: PIMPY
  name: Publicly Available Content Database
  url: http://search.proquest.com/publiccontent
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Public Health
EISSN 2036-7449
ExternalDocumentID oai_doaj_org_article_db0bddfd3a2c4f66aa02e2e31df86c71
40981333
10_3390_idr17050113
Genre Journal Article
GeographicLocations Italy
Southeast Asia
Spain
GeographicLocations_xml – name: Southeast Asia
– name: Spain
– name: Italy
GroupedDBID ---
53G
5VS
67V
7X2
7X7
8C1
8FI
8FJ
AAYXX
ABDBF
ABUWG
ACUHS
ADBBV
AFFHD
AFKRA
AFZYC
ALMA_UNASSIGNED_HOLDINGS
AOIJS
ATCPS
BAEHF
BAWUL
BCNDV
BENPR
BHPHI
CCPQU
CITATION
DIK
E3Z
EBD
ESX
F5P
FYUFA
GROUPED_DOAJ
HCIFZ
HMCUK
HYE
IAO
IHR
INH
ITC
KQ8
M0K
M48
MODMG
M~E
OK1
OZF
P6G
PATMY
PGMZT
PHGZM
PHGZT
PIMPY
PJZUB
PPXIY
PYCSY
RPM
TR2
TUS
UKHRP
NPM
3V.
7XB
8FE
8FH
8FK
AZQEC
COVID
DWQXO
GNUQQ
K9.
PKEHL
PQEST
PQQKQ
PQUKI
PRINS
7X8
ID FETCH-LOGICAL-c447t-62ef27c814fe456cbf2e1c1a808d4110c79530d4577784b0eb5c32aa4de00c5e3
IEDL.DBID BENPR
ISICitedReferencesCount 0
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001601666500001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 2036-7449
2036-7430
IngestDate Mon Nov 03 21:54:05 EST 2025
Mon Sep 22 19:30:51 EDT 2025
Tue Oct 28 21:17:08 EDT 2025
Fri Sep 26 01:51:19 EDT 2025
Sat Nov 29 07:18:13 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Keywords warning signs
Italy
dengue fever
travelers
imported
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c447t-62ef27c814fe456cbf2e1c1a808d4110c79530d4577784b0eb5c32aa4de00c5e3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ORCID 0000-0001-6587-4794
0000-0003-3685-4289
0000-0002-1490-636X
0000-0001-5999-006X
0000-0003-0569-9407
0000-0002-9414-0287
OpenAccessLink https://www.proquest.com/docview/3265910697?pq-origsite=%requestingapplication%
PMID 40981333
PQID 3265910697
PQPubID 4770003
ParticipantIDs doaj_primary_oai_doaj_org_article_db0bddfd3a2c4f66aa02e2e31df86c71
proquest_miscellaneous_3253043475
proquest_journals_3265910697
pubmed_primary_40981333
crossref_primary_10_3390_idr17050113
PublicationCentury 2000
PublicationDate 2025-09-12
PublicationDateYYYYMMDD 2025-09-12
PublicationDate_xml – month: 09
  year: 2025
  text: 2025-09-12
  day: 12
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Infectious disease reports
PublicationTitleAlternate Infect Dis Rep
PublicationYear 2025
Publisher MDPI AG
Publisher_xml – name: MDPI AG
References Cattaneo (ref_3) 2025; 51
Powell (ref_5) 2018; 98
Huits (ref_21) 2023; 176
Ahmed (ref_23) 2020; 30
ref_14
ref_12
ref_11
Adams (ref_1) 2024; 403
ref_10
ref_31
Duvignaud (ref_17) 2024; 31
Rovida (ref_7) 2025; 64
ref_16
Lachmann (ref_33) 2025; 32
Chen (ref_20) 2023; 30
Majumdar (ref_27) 2023; 156
Malafa (ref_29) 2023; 95
Holmes (ref_2) 1998; 54
Calleri (ref_18) 2017; 110
Cooper (ref_25) 2014; 21
Pagani (ref_24) 2020; 2
Santilli (ref_6) 2025; 53
(ref_15) 2021; 28
Neumayr (ref_32) 2017; 22
Trojanek (ref_22) 2016; 14
Moschetta (ref_13) 2023; 23
ref_28
Powell (ref_4) 2019; 67
ref_26
Maeki (ref_30) 2023; 29
Barzon (ref_9) 2021; 28
Tavakolipoor (ref_19) 2016; 14
Vita (ref_8) 2024; 62
References_xml – volume: 62
  start-page: 102762
  year: 2024
  ident: ref_8
  article-title: Dengue fever as autochthonous infectious disease in Italy: Epidemiological, clinical and virological characteristics
  publication-title: Travel Med. Infect. Dis.
  doi: 10.1016/j.tmaid.2024.102762
– ident: ref_11
  doi: 10.37573/9781585285495
– volume: 32
  start-page: taaf037
  year: 2025
  ident: ref_33
  article-title: Dengue virus infection in travellers after dengue vaccination, Germany 2023–24
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taaf037
– ident: ref_16
– volume: 30
  start-page: e2093
  year: 2020
  ident: ref_23
  article-title: Prevalence and burden of dengue infection in Europe: A systematic review and meta-analysis
  publication-title: Rev. Med. Virol.
  doi: 10.1002/rmv.2093
– volume: 64
  start-page: 102795
  year: 2025
  ident: ref_7
  article-title: Lombardy Dengue Network. The 2023 dengue outbreak in Lombardy, Italy: A one-health perspective
  publication-title: Travel Med. Infect. Dis.
  doi: 10.1016/j.tmaid.2025.102795
– volume: 156
  start-page: 608
  year: 2023
  ident: ref_27
  article-title: A retrospective analysis of serological & molecular testing data on dengue fever in Kolkata & adjacent districts during 2016–2019
  publication-title: Indian J. Med. Res.
  doi: 10.4103/ijmr.IJMR_2612_19
– ident: ref_14
– volume: 2
  start-page: 243
  year: 2020
  ident: ref_24
  article-title: Imported dengue fever: A 16-years retrospective analysis in Milan (Italy) and a brief review of the European literature
  publication-title: Infez. Med.
– volume: 53
  start-page: 1213
  year: 2025
  ident: ref_6
  article-title: Outbreak of autochthonous dengue in Fano, Pesaro-Urbino Province-Marche region, Italy, September 2024
  publication-title: Infection
  doi: 10.1007/s15010-025-02476-1
– volume: 176
  start-page: 940
  year: 2023
  ident: ref_21
  article-title: Clinical Characteristics and Outcomes Among Travelers With Severe Dengue: A GeoSentinel Analysis
  publication-title: Ann. Intern. Med.
  doi: 10.7326/M23-0721
– volume: 14
  start-page: 32
  year: 2016
  ident: ref_22
  article-title: Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre
  publication-title: Travel Med. Infect. Dis.
  doi: 10.1016/j.tmaid.2015.06.005
– ident: ref_26
  doi: 10.3390/ijms26146609
– volume: 51
  start-page: 101231
  year: 2025
  ident: ref_3
  article-title: Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007–2023: A systematic review and secondary analysis
  publication-title: Lancet Reg. Health-Eur.
– volume: 67
  start-page: 191
  year: 2019
  ident: ref_4
  article-title: Aedes aegypti vector competence studies: A review
  publication-title: Infect. Genet. Evol.
  doi: 10.1016/j.meegid.2018.11.009
– volume: 22
  start-page: 30433
  year: 2017
  ident: ref_32
  article-title: Sentinel surveillance of imported dengue via travellers to Europe 2012 to 2014: TropNet data from the DengueTools Research Initiative
  publication-title: Eurosurveillance
  doi: 10.2807/1560-7917.ES.2017.22.1.30433
– volume: 31
  start-page: taae089
  year: 2024
  ident: ref_17
  article-title: Epidemiology of travel-associated dengue from 2007 to 2022: A GeoSentinel analysis
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taae089
– volume: 403
  start-page: 667
  year: 2024
  ident: ref_1
  article-title: Dengue
  publication-title: Lancet
  doi: 10.1016/S0140-6736(23)02576-X
– ident: ref_31
– volume: 21
  start-page: 235
  year: 2014
  ident: ref_25
  article-title: Laboratory features of common causes of fever in returned travelers
  publication-title: J. Travel Med.
  doi: 10.1111/jtm.12122
– ident: ref_12
– ident: ref_10
– volume: 28
  start-page: taab130
  year: 2021
  ident: ref_9
  article-title: Autochthonous dengue outbreak in Italy 2020: Clinical, virological and entomological findings
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taab130
– volume: 23
  start-page: e455
  year: 2023
  ident: ref_13
  article-title: Mpox neutralising antibodies at 6 months from mpox infection or MVA-BN vaccination: A comparative analysis
  publication-title: Lancet Infect. Dis.
  doi: 10.1016/S1473-3099(23)00571-6
– ident: ref_28
  doi: 10.3389/fcimb.2022.975398
– volume: 95
  start-page: e29245
  year: 2023
  ident: ref_29
  article-title: Effect of previous heterologous flavivirus vaccinations on human antibody responses in tick-borne encephalitis and dengue virus infections
  publication-title: J. Med. Virol.
  doi: 10.1002/jmv.29245
– volume: 28
  start-page: TAAB183
  year: 2021
  ident: ref_15
  article-title: Dengue during the COVID-19 pandemic
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taab183
– volume: 54
  start-page: 533
  year: 1998
  ident: ref_2
  article-title: Molecular epidemiology and evolution of emerging infectious diseases
  publication-title: Br. Med. Bull.
  doi: 10.1093/oxfordjournals.bmb.a011708
– volume: 14
  start-page: 39
  year: 2016
  ident: ref_19
  article-title: Clinical features and laboratory findings of dengue fever in German travellers: A single-centre, retrospective analysis
  publication-title: Travel Med. Infect. Dis.
  doi: 10.1016/j.tmaid.2016.01.007
– volume: 110
  start-page: 13
  year: 2017
  ident: ref_18
  article-title: Imported dengue in two tertiary Italian hospitals: Use of rapid diagnostic tests
  publication-title: Bull. Soc. Pathol. Exot.
  doi: 10.1007/s13149-017-0542-x
– volume: 30
  start-page: taad127
  year: 2023
  ident: ref_20
  article-title: Epidemiology and burden of dengue fever in the United States: A systematic review
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taad127
– volume: 29
  start-page: 469
  year: 2023
  ident: ref_30
  article-title: Analysis of cross-reactivity among flaviviruses using sera of patients with dengue showed the importance of neutralization tests with paired serum samples for the correct interpretations of serological test results for dengue
  publication-title: J. Infect. Chemother.
  doi: 10.1016/j.jiac.2023.01.015
– volume: 98
  start-page: 1563
  year: 2018
  ident: ref_5
  article-title: Mosquito-borne human viral diseases: Why Aedes aegypti?
  publication-title: Am. J. Trop. Med. Hyg.
  doi: 10.4269/ajtmh.17-0866
SSID ssj0000396473
Score 2.325979
Snippet Background: Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing...
Dengue fever is an arboviral infection transmitted by mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks of...
Dengue fever is an arboviral infection transmitted by Aedes mosquitoes that has recently become a public health concern also in Europe, causing many outbreaks...
SourceID doaj
proquest
pubmed
crossref
SourceType Open Website
Aggregation Database
Index Database
StartPage 113
SubjectTerms Antibodies
Blood
Chikungunya virus
Cross-reactivity
Dengue fever
Dengue hemorrhagic fever
Emergency medical care
Epidemics
Hospitals
Immunization
Immunoglobulin G
Immunoglobulin M
imported
Italy
Laboratories
Leukopenia
Mosquitoes
Myalgia
Pandemics
Patients
Plasma
Polymerase chain reaction
Public health
Real time
Serology
Serotypes
Thrombocytopenia
travelers
Urine
Vector-borne diseases
Viral diseases
warning signs
West Nile virus
Zika virus
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LT9wwEB5ViEMlhEpbIBQqI3FsRGI7ccINaLfsoQjxkOAU-TFGK0EW7aPS_vuOnd3VckBcek2syPlmnPkm9nwDcESLyGIhstQG4VaK-C7VuRap81J4VWrhaxObTajLy-r-vr5aafUVzoR18sAdcMfOZMY574TmVvqy1DrjyFHkzleljdXjnFjPSjIVv8EiVFiKriBPUF5_PHCjoBxD7ixehaCo1P82vYxhpvcJNuf8kJ1289qCD9h-ho3u5xrraoa-wO_-c9Qjd-wnto9TZD0kj2SDlv0ZPOn2B-sTpZ6dsFN2EwSa0gdyZ3aNk9FwUVjJwvnB2Ve46_26Pb9I5x0RUiulmqQlR8-VrXLpkZiPNZ5jbnNdZZWTFMitqgl3JwulVCVNhqawgmstHWaZLVBsw1o7bHEXWFYrI2pHBsydlJSESJ8XxpVc0eMqIxM4WoDUvHTCFw0lDAHLZgXLBM4CgMshQa06XiAbNnMbNu_ZMIH9BfzNfAmNG-KVBXGZslYJHC5vk_OHHQ3d4nAaxtDrSiFVkcBOZ7blTChxrSgBF3v_Y4bf4CMPjX9j74h9WJuMpngA6_bvZDAefY--9w8QZt4l
  priority: 102
  providerName: Directory of Open Access Journals
Title Imported Dengue Fever in Milan, Italy: A Seven-Year Retrospective Study
URI https://www.ncbi.nlm.nih.gov/pubmed/40981333
https://www.proquest.com/docview/3265910697
https://www.proquest.com/docview/3253043475
https://doaj.org/article/db0bddfd3a2c4f66aa02e2e31df86c71
Volume 17
WOSCitedRecordID wos001601666500001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: DOA
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: M~E
  dateStart: 20090101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
– providerCode: PRVPQU
  databaseName: Agriculture Science Database
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: M0K
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/agriculturejournals
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Environmental Science Database
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: PATMY
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: http://search.proquest.com/environmentalscience
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central (New)
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: BENPR
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Health & Medical Collection
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: 7X7
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Public Health Database
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: 8C1
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/publichealth
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Publicly Available Content Database
  customDbUrl:
  eissn: 2036-7449
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000396473
  issn: 2036-7449
  databaseCode: PIMPY
  dateStart: 20090901
  isFulltext: true
  titleUrlDefault: http://search.proquest.com/publiccontent
  providerName: ProQuest
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB7RLQckxLsQKCsj9UhUO3ZihwtqSxdWaFdRAWl7ihw_qpUgKdldpP57xkl2gQNcuPiQWJaTmfG8PN8AHKEQGZdyGpsA3Ioa38aaaR5bL7iXmeY-r7pmE3I-V4tFXgwBt9VwrXJ7JnYHtW1MiJEfo5mRomrLcvn2-nscukaF7OrQQmMP9gNSmRjB_un5vLjYRVkoD5WWIc0cEm4xqkvaF-lx9PWPl7YNaDLI4vwPtdSh9__d5OxUz-T-_276AdwbjE5y0nPJQ7jl6kdwt4_Ykb4Q6TG8n37rQM4teefqq40jE4dsTpY1mS2_6vo1maKdfvOGnJBPAfUpvkQZIRdu3Tbbak0SLiXePIEvk_PPZx_ioc1CbISQ6zhLnE-kUUx4h-aUqXzimGFaUWUFWgdG5khMK1IppRIVdVVqeKK1sI5Skzp-AKO6qd0zIDSXFc8tcgWzQqBnIzxLK5slEpdTlYjgaPuXy-seTaNELyQQo_yNGBGcBgrspgQI7O5B016Vg0SVtqKVtd5ynRjhs0xrmrjEcWa9yoxkERxuaVIOcrkqfxEkgle71yhRIU2ia9dswhz8XMGFTCN42tN9txP0hhV69fz5vxd_AXeS0Ce4azVxCKN1u3Ev4bb5sV6u2jHsyYXsRoWjOmPjgW3HXUQAxxn9iOO8mOGbYjorLn8Cztv02A
linkProvider ProQuest
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VLRJIiPcjUMBI5UZUx3ZiBwmhQlkatbtaQSu1p-DYTrUSZEt2F7R_it_IOI8FDnDrgWtsWXbmm5fHMwOwjUxkXMxpaHzhVtT4NtSR5qEtBS9lonmZFk2zCTkeq5OTdLIBP_pcGP-sspeJjaC2M-PvyHfQzIhRtSWpfH3-NfRdo3x0tW-h0cLiwK2-o8s2f5XtIX2fMzZ8d_R2P-y6CoRGCLkIE-ZKJo2KROnQejBFyVxkIq2osgKVoZEp7t2KWEqpREFdERvOtBbWUWpix3HdS7ApEOxqAJuTbDQ5Xd_qUO4zO31Y2wf4QlTPtE0K5DylO1Nb--o1yFL8DzXYdAv4u4nbqLrhjf_tJ92E651RTXZbLrgFG666DdfaG0nSJlrdgffZl6aIuyV7rjpbOjJ0yMZkWpHR9LOuXpAM_ZDVS7JLPvqqVuEpnoN8cIt61mejEv_ocnUXji_kLPdgUM0q9wAITWXBU4uoj6xABChRRnFhEyZxOVWIALZ7qubnbbWQHL0sT_z8N-IH8MZTfD3Fl_huPszqs7yTGLktaGFtablmRpRJojVljjke2VIlRkYBbPUYyDu5M89_ASCAZ-thlBg-DKQrN1v6OXhcwYWMA7jf4my9E_T2VcQ5f_jvxZ_Clf2j0WF-mI0PHsFV5nsiN201tmCwqJfuMVw23xbTef2kYxACny4abj8BEshKUQ
linkToPdf http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Ji9RAFH6Mo4gg7kt01BLGm6FrSyoRRMZpW5vRZnCB8RQrtQwNmozpbqX_mr_OV1laPehtDl6ToshLfW-rtwHsIhMZlwgam9C4FTW-jTXTIrZeCq9SLXxetsMm1GyWHR3lh1vwY6iFCWmVg0xsBbWtTbgjH6GZkaBqS3M18n1axOF48uzkaxwmSIVI6zBOo4PIgVt_R_dt8XQ6xrN-xPnkxfv9V3E_YSA2UqplnHLnuTIZk96hJWFKzx0zTGc0sxIVo1E50mFlopTKZEldmRjBtZbWUWoSJ3DfM3BWCURxqFLfZ5v7HSpCjWcIcIdQX4yKmnblgULkdDS3Tehjg8wl_lCI7dyAvxu7rdKbXP6ff9cVuNSb2mSv442rsOWqa3Cxu6ckXfnVdXg5_dK2drdk7KrjlSMTh8xN5hV5M_-sq8dkit7J-gnZI-9Cr6v4I9JB3rplUw81qiSkYq5vwIdToeUmbFd15W4DobkqRW6RF5iVEv056VlS2pQr3C4rZQS7wwkXJ10PkQJ9rwCE4jcgRPA8nP5mSWj83T6om-OilyOFLWlprbdCcyN9mmpNueNOMOuz1CgWwc6Ah6KXRoviFxgieLh5jXIkBId05epVWIPkSiFVEsGtDnObL5E0z5gQ4s6_N38A5xFjxevp7OAuXOBhUHI7a2MHtpfNyt2Dc-bbcr5o7recQuDTaWPtJ_8EUUk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Imported+Dengue+Fever+in+Milan%2C+Italy%3A+A+Seven-Year+Retrospective+Study&rft.jtitle=Infectious+disease+reports&rft.au=Pieruzzi%2C+Margherita+Eleonora&rft.au=Mileto%2C+Davide&rft.au=Behring%2C+Alessandra+Helen&rft.au=Caronni%2C+Stefania&rft.date=2025-09-12&rft.issn=2036-7449&rft.eissn=2036-7449&rft.volume=17&rft.issue=5&rft.spage=113&rft_id=info:doi/10.3390%2Fidr17050113&rft.externalDBID=n%2Fa&rft.externalDocID=10_3390_idr17050113
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2036-7449&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2036-7449&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2036-7449&client=summon